STRINGSTRING
cysC cysC cysD cysD CUQ66245.1 CUQ66245.1 CUQ66246.1 CUQ66246.1 CUQ66247.1 CUQ66247.1 CUQ66248.1 CUQ66248.1 cysH cysH cysD-2 cysD-2 cysNC cysNC hemL hemL CUQ66666.1 CUQ66666.1 CUQ66837.1 CUQ66837.1 CUQ66838.1 CUQ66838.1 CUQ66839.1 CUQ66839.1 CUQ66840.1 CUQ66840.1 CUQ66841.1 CUQ66841.1 CUQ66842.1 CUQ66842.1 CUQ66843.1 CUQ66843.1 CUQ66845.1 CUQ66845.1 hemE hemE hemH hemH hemY hemY CUQ67447.1 CUQ67447.1 CUQ67448.1 CUQ67448.1 hemA hemA hemC hemC hemD hemD CUQ67452.1 CUQ67452.1 hemB hemB ribF ribF tilS tilS hpt hpt ftsH-2 ftsH-2 CUQ67458.1 CUQ67458.1 CUQ67466.1 CUQ67466.1 tyrS tyrS CUQ67468.1 CUQ67468.1 CUQ67515.1 CUQ67515.1 CUQ67517.1 CUQ67517.1 CUQ67518.1 CUQ67518.1 btuC btuC CUQ67520.1 CUQ67520.1 CUQ67521.1 CUQ67521.1 yvqK yvqK cobU cobU cobT cobT cobS cobS cobD cobD cobD-2 cobD-2 CUQ67529.1 CUQ67529.1 CUQ67534.1 CUQ67534.1 CUQ67535.1 CUQ67535.1 CUQ67858.1 CUQ67858.1 CUQ67859.1 CUQ67859.1 CUQ67860.1 CUQ67860.1 CUQ67861.1 CUQ67861.1 cysC-2 cysC-2 CUQ68244.1 CUQ68244.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cysCPutative adenylyl-sulfate kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the APS kinase family. (178 aa)
cysDSulfate adenylyltransferase, subunit 2. (265 aa)
CUQ66245.1Homologs of previously reported genes of unknown function. (199 aa)
CUQ66246.1Protein of unknown function; No homology to any previously reported sequences. (93 aa)
CUQ66247.1Putative HTH-type transcriptional regulator, rrf2 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (149 aa)
CUQ66248.1Putative Sulfite reductase, contains SirA-like domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (834 aa)
cysHPhosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (238 aa)
cysD-2Sulfate adenylyltransferase, subunit 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (265 aa)
cysNCSulfate adenylyltransferase, subunit 1, and adenylylsulfate kinase (bifunctional enzyme); Function of strongly homologous gene; enzyme. (621 aa)
hemLGlutamate-1-semialdehyde aminotransferase (aminomutase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (454 aa)
CUQ66666.1Aminotransferase class-III (modular protein). (785 aa)
CUQ66837.1Homologs of previously reported genes of unknown function. (190 aa)
CUQ66838.1Cobalamin (Vitamin B12) biosynthesis CbiX protein. (310 aa)
CUQ66839.1Protein of unknown function; No homology to any previously reported sequences. (405 aa)
CUQ66840.1Putative TonB-dependent receptor plug; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (762 aa)
CUQ66841.1Putative Variant PEP-CTERM exosortase signal; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (255 aa)
CUQ66842.1Protein of unknown function; No homology to any previously reported sequences. (77 aa)
CUQ66843.1Homologs of previously reported genes of unknown function. (562 aa)
CUQ66845.1Protein of unknown function; No homology to any previously reported sequences. (71 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (344 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (316 aa)
hemYProtoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX. (484 aa)
CUQ67447.1Putative Ribosomal RNA small subunit methyltransferase I; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (259 aa)
CUQ67448.1Putative Cytochrome c biogenesis protein CcsA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (267 aa)
hemAGlutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (458 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (316 aa)
hemDPorphyrin biosynthesis protein HemD. (526 aa)
CUQ67452.1Homologs of previously reported genes of unknown function. (131 aa)
hemBPorphobilinogen synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family. (323 aa)
ribFRiboflavin biosynthesis protein RibF; Belongs to the ribF family. (326 aa)
tilStRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (495 aa)
hptHypoxanthine-guanine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (182 aa)
ftsH-2Protease, ATP-dependent zinc-metallo; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (604 aa)
CUQ67458.1Protein of unknown function; No homology to any previously reported sequences. (70 aa)
CUQ67466.1Homologs of previously reported genes of unknown function. (169 aa)
tyrSTyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. (409 aa)
CUQ67468.1Putative Helix-turn-helix, type 11 domain protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (327 aa)
CUQ67515.1Protein of unknown function; No homology to any previously reported sequences. (31 aa)
CUQ67517.1Protein of unknown function; No homology to any previously reported sequences. (45 aa)
CUQ67518.1Putative Vitamin B12 import system, periplasmic binding protein BtuF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (366 aa)
btuCVitamin B12 import system, permease protein BtuC; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily. (391 aa)
CUQ67520.1Putative Vitamin B12 import system, ATP-binding protein BtuD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (298 aa)
CUQ67521.1Putative Carbon-nitrogen hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (256 aa)
yvqKCob(I)yrinic acid a,c-diamide adenosyltransferase; Belongs to the Cob(I)alamin adenosyltransferase family. (203 aa)
cobUBifunctional cobinamide kinase and cobinamide phosphate guanylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (186 aa)
cobTNicotinate-nucleotide dimethylbenzimidazole-P phophoribosyl transferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (353 aa)
cobSCobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (254 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (320 aa)
cobD-2Threonine-phosphate decarboxylase. (369 aa)
CUQ67529.1Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (248 aa)
CUQ67534.1Protein of unknown function; No homology to any previously reported sequences. (312 aa)
CUQ67535.1Homologs of previously reported genes of unknown function. (175 aa)
CUQ67858.1Homologs of previously reported genes of unknown function. (102 aa)
CUQ67859.1Putative Precorrin-2 dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (217 aa)
CUQ67860.1Putative HNH endonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (181 aa)
CUQ67861.1Putative Rieske-type ferredoxin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (121 aa)
cysC-2Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. (205 aa)
CUQ68244.1Putative N-carbamoyl-D-amino acid hydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (263 aa)
Your Current Organism:
Nitrospira inopinata
NCBI taxonomy Id: 1715989
Other names: C. Nitrospira inopinata, Candidatus Nitrospira inopinata, Nitrospira sp. ENR4
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