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gcvT gcvT CUQ65922.1 CUQ65922.1 CUQ65923.1 CUQ65923.1 CUQ65924.1 CUQ65924.1 gcvP gcvP gdhA gdhA lipB lipB glnA glnA CUQ66890.1 CUQ66890.1 lipA lipA gcvH gcvH lpd lpd gltD gltD gltB gltB
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
CUQ65922.1Branched-chain alpha-keto acid dehydrogenase, dihydrolipoamide acyltransferase (E2) component; Function of strongly homologous gene; enzyme. (401 aa)
CUQ65923.1Putative Pyruvate dehydrogenase E1 component, subunit beta; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (330 aa)
CUQ65924.1Putative Pyruvate dehydrogenase E1 component, subunit alpha; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (333 aa)
gcvPGlycine decarboxylase, PLP-dependent, subunit (protein P) of glycine cleavage complex; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
gdhAGlutamate dehydrogenase; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (418 aa)
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (282 aa)
glnAGlutamine synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (469 aa)
CUQ66890.1Putative Aminomethyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the GcvT family. (363 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (313 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
lpdDihydrolipoyl dehydrogenase, E3 component of Pyruvate and 2-oxoglutarate dehydrogenase complexes; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (477 aa)
gltDGlutamate synthase [NADPH] small chain. (478 aa)
gltBGlutamate synthase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (1505 aa)
Your Current Organism:
Nitrospira inopinata
NCBI taxonomy Id: 1715989
Other names: C. Nitrospira inopinata, Candidatus Nitrospira inopinata, Nitrospira sp. ENR4
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