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sucC sucC idh idh acnA acnA aclA aclA mdh mdh purU purU sdhC sdhC sdhA-2 sdhA-2 sdhB sdhB CUQ66453.1 CUQ66453.1 fumC fumC maeB maeB gltA gltA
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
Your Input:
sucCsuccinyl-CoA synthetase, beta subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (392 aa)
idhIsocitrate dehydrogenase (NADP(+)); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the monomeric-type IDH family. (743 aa)
acnAAconitate hydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (748 aa)
aclAATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (606 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (340 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (288 aa)
sdhCSuccinate dehydrogenase/fumarate reductase, cytochrome b558 subunit; Function of strongly homologous gene; enzyme. (226 aa)
sdhA-2Succinate dehydrogenase or fumarate reductase, flavoprotein subunit; Function of strongly homologous gene; enzyme. (638 aa)
sdhBSuccinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (262 aa)
CUQ66453.1Isocitrate dehydrogenase (NAD+). (338 aa)
fumCFumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (479 aa)
maeBMalate dehydrogenase (oxaloacetate-decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (482 aa)
gltACitrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family. (377 aa)
Your Current Organism:
Nitrospira inopinata
NCBI taxonomy Id: 1715989
Other names: C. Nitrospira inopinata, Candidatus Nitrospira inopinata, Nitrospira sp. ENR4
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