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CUQ67387.1 CUQ67387.1 capL capL leuB leuB ilvC ilvC hisD hisD rkpK rkpK idh idh murB murB CUQ65392.1 CUQ65392.1 CUQ65395.1 CUQ65395.1 adhC adhC CUQ65534.1 CUQ65534.1 rfbD rfbD zwf zwf hom hom mmgB mmgB mdh mdh pdxA pdxA gpsA gpsA tiaE tiaE aroE aroE CUQ66452.1 CUQ66452.1 CUQ66453.1 CUQ66453.1 adhA adhA tdh tdh dxr dxr zwf-2 zwf-2 yqeC yqeC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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CUQ67387.1Putative chlorophyll synthesis pathway protein BchC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (371 aa)
capLProtein CapL; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (431 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (357 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (427 aa)
rkpKUDP-glucose 6-dehydrogenase. (441 aa)
idhIsocitrate dehydrogenase (NADP(+)); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the monomeric-type IDH family. (743 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase 2; Cell wall formation. (306 aa)
CUQ65392.1GroES-like protein. (731 aa)
CUQ65395.1Protein of unknown function; No homology to any previously reported sequences. (106 aa)
adhCAlcohol dehydrogenase, NADP-dependent; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (347 aa)
CUQ65534.1Zn-dependent alcohol dehydrogenase. (338 aa)
rfbDdTDP-4-dehydrorhamnose reductase; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose. (280 aa)
zwfGlucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (455 aa)
homHomoserine dehydrogenase. (437 aa)
mmgBPutative 3-hydroxybutyryl-CoA dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme;fragment of methylmalonyl-CoA mutase (part 1). (296 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (340 aa)
pdxA4-hydroxy-L-threonine phosphate dehydrogenase, NAD-dependent; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (354 aa)
gpsAGlycerol-3-phosphate dehydrogenase [NAD(P)+]; Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family. (339 aa)
tiaE2-oxo-carboxylic acid reductase (glyoxalate reductase) (2-ketoaldonate reductase); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (319 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (284 aa)
CUQ66452.1Putative isocitrate dehydrogenase (NADP); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (117 aa)
CUQ66453.1Isocitrate dehydrogenase (NAD+). (338 aa)
adhAPutative alcohol dehydrogenase AdhA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (336 aa)
tdhThreonine 3-dehydrogenase, NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (344 aa)
dxr1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (386 aa)
zwf-2Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (518 aa)
yqeCPutative 6-phosphogluconate dehydrogenase YqeC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (297 aa)
Your Current Organism:
Nitrospira inopinata
NCBI taxonomy Id: 1715989
Other names: C. Nitrospira inopinata, Candidatus Nitrospira inopinata, Nitrospira sp. ENR4
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