(7 nodes) Thiamine pyrophosphate binding network (Nitrospira inopinata)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ilvI	Acetolactate synthase III, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (591 aa)
	forB	2-oxoglutarate:ferredoxin oxidoredutase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (300 aa)
	comE	Sulfopyruvate decarboxylase subunit beta. (192 aa)
	comD	Sulfopyruvate decarboxylase, alpha subunit. (165 aa)
	dxs	1-deoxy-D-xylulose-5-phosphate synthase 1; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (647 aa)
	porB	Pyruvate:ferredoxin oxidoreductase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (302 aa)
	CUQ67167.1	Putative Pyruvate decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (551 aa)

Your Current Organism:

Nitrospira inopinata

NCBI taxonomy Id: 1715989
Other names: C. Nitrospira inopinata, Candidatus Nitrospira inopinata, Nitrospira sp. ENR4

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
comD	comE	NITINOP_0317	NITINOP_0316	Sulfopyruvate decarboxylase, alpha subunit.	Sulfopyruvate decarboxylase subunit beta.	0.998
comE	comD	NITINOP_0316	NITINOP_0317	Sulfopyruvate decarboxylase subunit beta.	Sulfopyruvate decarboxylase, alpha subunit.	0.998
forB	ilvI	NITINOP_0242	NITINOP_0105	2-oxoglutarate:ferredoxin oxidoredutase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Acetolactate synthase III, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.907
forB	porB	NITINOP_0242	NITINOP_1629	2-oxoglutarate:ferredoxin oxidoredutase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Pyruvate:ferredoxin oxidoreductase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.906
ilvI	forB	NITINOP_0105	NITINOP_0242	Acetolactate synthase III, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	2-oxoglutarate:ferredoxin oxidoredutase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.907
ilvI	porB	NITINOP_0105	NITINOP_1629	Acetolactate synthase III, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Pyruvate:ferredoxin oxidoreductase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.907
porB	forB	NITINOP_1629	NITINOP_0242	Pyruvate:ferredoxin oxidoreductase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	2-oxoglutarate:ferredoxin oxidoredutase beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.906
porB	ilvI	NITINOP_1629	NITINOP_0105	Pyruvate:ferredoxin oxidoreductase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	Acetolactate synthase III, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.907