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hemH hemH hemF hemF hemA hemA hemL hemL AOT82_1697 AOT82_1697 hemC hemC AOT82_1849 AOT82_1849 AOT82_2216 AOT82_2216 AOT82_2256 AOT82_2256 AOT82_2257 AOT82_2257 AOT82_2261 AOT82_2261 AOT82_2262 AOT82_2262 AOT82_2263 AOT82_2263 ccmC ccmC AOT82_2265 AOT82_2265 ccmE ccmE hemE hemE AOT82_941 AOT82_941 AOT82_942 AOT82_942 AOT82_943 AOT82_943 AOT82_944 AOT82_944 AOT82_962 AOT82_962
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (339 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (332 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (460 aa)
hemLGlutamate-1-semialdehyde 2,1-aminomutase. (433 aa)
AOT82_1697Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (343 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (347 aa)
AOT82_1849Oxygen-independent coproporphyrinogen III oxidase. (523 aa)
AOT82_2216Hypothetical protein. (144 aa)
AOT82_2256Hypothetical protein. (68 aa)
AOT82_2257Hypothetical protein. (305 aa)
AOT82_2261Heme exporter protein A1; Part of the ABC transporter complex CcmAB involved in the biogenesis of c-type cytochromes; once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system. (209 aa)
AOT82_2262Hypothetical protein. (63 aa)
AOT82_2263Heme exporter protein B1; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmB/CycW/HelB family. (248 aa)
ccmCHeme exporter protein C1; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmC/CycZ/HelC family. (262 aa)
AOT82_2265Hypothetical protein; Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes; Belongs to the CcmD/CycX/HelD family. (73 aa)
ccmECytochrome c-type biogenesis protein E1; Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH. Belongs to the CcmE/CycJ family. (166 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (378 aa)
AOT82_941NrfG protein. (426 aa)
AOT82_942Heme lyase subunit; Possible subunit of a heme lyase. (185 aa)
AOT82_943Thiol:disulfide interchange protein. (216 aa)
AOT82_944Cytochrome c-type biogenesis protein. (676 aa)
AOT82_962Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (335 aa)
Your Current Organism:
Psychrobacter sp. AntiMn1
NCBI taxonomy Id: 1720344
Other names: P. sp. AntiMn-1, Psychrobacter sp. AntiMn-1
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