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rlpA rlpA ppnP ppnP purF purF mltG mltG pncB pncB AOT82_1160 AOT82_1160 mrdA mrdA AOT82_179 AOT82_179 AOT82_860 AOT82_860 AOT82_776 AOT82_776 ppnP-2 ppnP-2 queA queA lpxB lpxB rlpA-2 rlpA-2 mrdB mrdB trpD trpD AOT82_388 AOT82_388 AOT82_296 AOT82_296 AOT82_2770 AOT82_2770 tgt tgt AOT82_268 AOT82_268 AOT82_2677 AOT82_2677 AOT82_2646 AOT82_2646 AOT82_262 AOT82_262 AOT82_2617 AOT82_2617 AOT82_2612 AOT82_2612 AOT82_2611 AOT82_2611 AOT82_261 AOT82_261 AOT82_260 AOT82_260 AOT82_2591 AOT82_2591 murG murG pyrE pyrE AOT82_2342 AOT82_2342 AOT82_2189 AOT82_2189 hisG hisG AOT82_2159 AOT82_2159 AOT82_2112 AOT82_2112 upp upp lgt lgt AOT82_202 AOT82_202 AOT82_1996 AOT82_1996 AOT82_1947 AOT82_1947 hisF hisF hisH hisH AOT82_1807 AOT82_1807 AOT82_1806 AOT82_1806 AOT82_1804 AOT82_1804 AOT82_180 AOT82_180
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
rlpARare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (120 aa)
ppnPHypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (111 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (511 aa)
mltGHypothetical protein; Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation. Belongs to the transglycosylase MltG family. (426 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (408 aa)
AOT82_1160Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors. Belongs to the glycosyltransferase 51 family. (185 aa)
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (661 aa)
AOT82_179Membrane-bound lytic murein transglycosylase d precursor. (1014 aa)
AOT82_860Hypothetical protein. (438 aa)
AOT82_776Hypothetical protein. (458 aa)
ppnP-2Hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. (94 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (400 aa)
lpxBlipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. (438 aa)
rlpA-2Rare lipoprotein A; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (204 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (380 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (373 aa)
AOT82_388Hypoxanthine-guanine phosphoribosyltransferase. (187 aa)
AOT82_296Adenine/guanine phosphoribosyltransferase. (188 aa)
AOT82_2770Penicillin-binding protein 1b; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (834 aa)
tgtQueuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (383 aa)
AOT82_268UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase. (375 aa)
AOT82_26773-deoxy-D-manno-octulosonic-acid transferase; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family. (515 aa)
AOT82_2646Lytic murein transglycosylase. (454 aa)
AOT82_262UDP-D-galactose:(glucosyl)lipopolysaccharide-1, 6-D-galactosyltransferase. (369 aa)
AOT82_2617Hypothetical protein. (375 aa)
AOT82_2612Glycosyl transferase family protein. (364 aa)
AOT82_2611Lipopolysaccharide N-acetylglucosaminyltransferase. (349 aa)
AOT82_261Lipopolysaccharide 1,6-galactosyltransferase. (359 aa)
AOT82_260Hypothetical protein. (288 aa)
AOT82_2591Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (286 aa)
murGUndecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. (361 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (238 aa)
AOT82_2342Lytic murein transglycosylase. (706 aa)
AOT82_2189Peptidoglycan synthetase. (881 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Short subfamily. (230 aa)
AOT82_2159Hypothetical protein; Belongs to the NAPRTase family. (465 aa)
AOT82_2112Lytic murein transglycosylase. (486 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (219 aa)
lgtProlipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (294 aa)
AOT82_202Hypothetical protein. (319 aa)
AOT82_1996Cell division protein; Belongs to the SEDS family. (398 aa)
AOT82_1947Penicillin-binding protein. (694 aa)
hisFImidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (260 aa)
hisHAmidotransferase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
AOT82_1807Putative glycosyl transferase. (384 aa)
AOT82_1806Putative glycosyltransferase. (423 aa)
AOT82_1804Hypothetical protein. (526 aa)
AOT82_180Transglycosylase. (401 aa)
Your Current Organism:
Psychrobacter sp. AntiMn1
NCBI taxonomy Id: 1720344
Other names: P. sp. AntiMn-1, Psychrobacter sp. AntiMn-1
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