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AOT82_2370 AOT82_2370 AOT82_1022 AOT82_1022 fumC fumC AOT82_1194 AOT82_1194 hutU hutU hutH hutH hutG hutG hutI hutI AOT82_1264 AOT82_1264 dapF dapF lysA lysA dapA dapA AOT82_1639 AOT82_1639 aroE aroE AOT82_1670 AOT82_1670 dapB dapB AOT82_2026 AOT82_2026 aroK aroK aroB aroB AOT82_2199 AOT82_2199 AOT82_222 AOT82_222 AOT82_223 AOT82_223 mdh mdh AOT82_2371 AOT82_2371 dapE dapE ilvE ilvE AOT82_2588 AOT82_2588 AOT82_2589 AOT82_2589 AOT82_2591 AOT82_2591 asd asd AOT82_2778 AOT82_2778 aroC aroC AOT82_299 AOT82_299 aroA aroA AOT82_303 AOT82_303 AOT82_304 AOT82_304 AOT82_323 AOT82_323 prpB prpB ppc ppc AOT82_452 AOT82_452 AOT82_53 AOT82_53 aroQ aroQ AOT82_582 AOT82_582 AOT82_622 AOT82_622 maeA maeA AOT82_731 AOT82_731 AOT82_805 AOT82_805 dapD dapD AOT82_911 AOT82_911 lpxL lpxL
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Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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AOT82_23707,8-dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (307 aa)
AOT82_1022Aspartate ammonia-lyase. (474 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (467 aa)
AOT82_1194Histidine utilization repressor. (250 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (570 aa)
hutHHistidine ammonia-lyase. (520 aa)
hutGFormiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (349 aa)
hutIImidazolonepropionase. (441 aa)
AOT82_1264Folylpolyglutamate synthase; Belongs to the folylpolyglutamate synthase family. (452 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa)
lysAHypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (458 aa)
dapADihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (301 aa)
AOT82_16394-amino-4-deoxychorismate lyase. (325 aa)
aroEShikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (287 aa)
AOT82_16702-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase. (169 aa)
dapBDihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (276 aa)
AOT82_2026Dihydrofolate reductase; Belongs to the dihydrofolate reductase family. (196 aa)
aroKShikimate kinase I; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (186 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa)
AOT82_2199Glutamate synthase subunit alpha. (1487 aa)
AOT82_222Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1082 aa)
AOT82_223Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase. (230 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family. (329 aa)
AOT82_2371Hypothetical protein. (93 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (405 aa)
ilvEBranched-chain amino-acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (309 aa)
AOT82_2588L-aspartate oxidase (quinolinate synthetase B); Catalyzes the oxidation of L-aspartate to iminoaspartate. (626 aa)
AOT82_2589Quinolinate synthetase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (379 aa)
AOT82_2591Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (286 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (377 aa)
AOT82_2778Aspartokinase; Belongs to the aspartokinase family. (428 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (367 aa)
AOT82_299Bifunctional chorismate mutase/prephenate dehydratase. (390 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (777 aa)
AOT82_303Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (145 aa)
AOT82_304Hypothetical protein. (167 aa)
AOT82_323Aromatic amino acid aminotransferase. (398 aa)
prpB2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (297 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (928 aa)
AOT82_452Glutamate dehydrogenase. (1614 aa)
AOT82_53Sodium/proline symporter (proline permease); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (499 aa)
aroQ3-dehydroquinate dehydratase II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (178 aa)
AOT82_582Phospho-2-dehydro-3-deoxyheptonate aldolase, tyr-sensitive; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (360 aa)
AOT82_622NADP-dependent malate dehydrogenase (decarboxylating); Belongs to the malic enzymes family. (772 aa)
maeAMalate dehydrogenase. (560 aa)
AOT82_731Transcriptional regulator; Belongs to the HpcH/HpaI aldolase family. (290 aa)
AOT82_805Glutamate synthase domain protein; Belongs to the glutamate synthase family. (607 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Belongs to the transferase hexapeptide repeat family. (273 aa)
AOT82_911Hypothetical protein. (234 aa)
lpxLPutative acyltransferase; Catalyzes the transfer of laurate from lauroyl-acyl carrier protein (ACP) to Kdo(2)-lipid IV(A) to form Kdo(2)-(lauroyl)-lipid IV(A). (363 aa)
Your Current Organism:
Psychrobacter sp. AntiMn1
NCBI taxonomy Id: 1720344
Other names: P. sp. AntiMn-1, Psychrobacter sp. AntiMn-1
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