STRINGSTRING
AOT82_104 AOT82_104 AOT82_1071 AOT82_1071 AOT82_1194 AOT82_1194 hutU hutU hutH hutH hutG hutG hutI hutI AOT82_1207 AOT82_1207 AOT82_1209 AOT82_1209 AOT82_1210 AOT82_1210 AOT82_1214 AOT82_1214 AOT82_1215 AOT82_1215 AOT82_1217 AOT82_1217 AOT82_1228 AOT82_1228 AOT82_1279 AOT82_1279 AOT82_133 AOT82_133 AOT82_1360 AOT82_1360 AOT82_1408 AOT82_1408 AOT82_1409 AOT82_1409 AOT82_1410 AOT82_1410 AOT82_1411 AOT82_1411 AOT82_1412 AOT82_1412 AOT82_1424 AOT82_1424 AOT82_143 AOT82_143 AOT82_1483 AOT82_1483 AOT82_1507 AOT82_1507 AOT82_1509 AOT82_1509 AOT82_1511 AOT82_1511 AOT82_1522 AOT82_1522 AOT82_1555 AOT82_1555 AOT82_156 AOT82_156 AOT82_1567 AOT82_1567 AOT82_157 AOT82_157 AOT82_1581 AOT82_1581 AOT82_1587 AOT82_1587 AOT82_1609 AOT82_1609 AOT82_1615 AOT82_1615 AOT82_1643 AOT82_1643 AOT82_1645 AOT82_1645 AOT82_1673 AOT82_1673 AOT82_1695 AOT82_1695 pnp pnp AOT82_1760 AOT82_1760 AOT82_1790 AOT82_1790 AOT82_1795 AOT82_1795 AOT82_180 AOT82_180 AOT82_1815 AOT82_1815 AOT82_1858 AOT82_1858 AOT82_1917 AOT82_1917 AOT82_1925 AOT82_1925 rppH rppH AOT82_206 AOT82_206 AOT82_2062 AOT82_2062 AOT82_2066 AOT82_2066 AOT82_207 AOT82_207 AOT82_2072 AOT82_2072 AOT82_208 AOT82_208 anmK anmK alc alc AOT82_2090 AOT82_2090 ureA ureA ureC ureC AOT82_2135 AOT82_2135 fadB fadB fadA fadA AOT82_2143 AOT82_2143 dtd dtd AOT82_2155 AOT82_2155 rph rph AOT82_222 AOT82_222 AOT82_223 AOT82_223 AOT82_2243 AOT82_2243 AOT82_2252 AOT82_2252 AOT82_2254 AOT82_2254 AOT82_2303 AOT82_2303 AOT82_2327 AOT82_2327 AOT82_2365 AOT82_2365 katG katG AOT82_2383 AOT82_2383 AOT82_2394 AOT82_2394 AOT82_2503 AOT82_2503 AOT82_2543 AOT82_2543 AOT82_2545 AOT82_2545 AOT82_2546 AOT82_2546 dut dut AOT82_2577 AOT82_2577 AOT82_2591 AOT82_2591 AOT82_2620 AOT82_2620 surE surE AOT82_2671 AOT82_2671 AOT82_276 AOT82_276 AOT82_277 AOT82_277 csrA csrA AOT82_2790 AOT82_2790 AOT82_2798 AOT82_2798 AOT82_294 AOT82_294 AOT82_295 AOT82_295 AOT82_309 AOT82_309 AOT82_318 AOT82_318 AOT82_322 AOT82_322 AOT82_325 AOT82_325 AOT82_326 AOT82_326 AOT82_34 AOT82_34 AOT82_347 AOT82_347 AOT82_348 AOT82_348 AOT82_349 AOT82_349 AOT82_35 AOT82_35 AOT82_350 AOT82_350 AOT82_352 AOT82_352 AOT82_358 AOT82_358 AOT82_402 AOT82_402 AOT82_403 AOT82_403 AOT82_452 AOT82_452 AOT82_47 AOT82_47 gloB gloB AOT82_510 AOT82_510 AOT82_53 AOT82_53 ilvA ilvA AOT82_544 AOT82_544 AOT82_580 AOT82_580 AOT82_590 AOT82_590 AOT82_591 AOT82_591 AOT82_593 AOT82_593 AOT82_594 AOT82_594 AOT82_595 AOT82_595 AOT82_603 AOT82_603 AOT82_606 AOT82_606 AOT82_607 AOT82_607 AOT82_70 AOT82_70 AOT82_718 AOT82_718 AOT82_721 AOT82_721 AOT82_722 AOT82_722 AOT82_723 AOT82_723 AOT82_733 AOT82_733 AOT82_734 AOT82_734 AOT82_744 AOT82_744 AOT82_779 AOT82_779 AOT82_785 AOT82_785 AOT82_80 AOT82_80 gcvT gcvT gcvH gcvH gcvP gcvP AOT82_84 AOT82_84 AOT82_864 AOT82_864 AOT82_865 AOT82_865 AOT82_867 AOT82_867 AOT82_873 AOT82_873
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AOT82_104Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. (536 aa)
AOT82_1071Morphogenesis-like protein. (216 aa)
AOT82_1194Histidine utilization repressor. (250 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (570 aa)
hutHHistidine ammonia-lyase. (520 aa)
hutGFormiminoglutamase; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. (349 aa)
hutIImidazolonepropionase. (441 aa)
AOT82_1207Xanthine dehydrogenase accessory factor. (430 aa)
AOT82_1209Hypothetical protein. (330 aa)
AOT82_1210Aerobic-type carbon monoxide dehydrogenase large subunit. (218 aa)
AOT82_1214Dihydropteridine reductase. (80 aa)
AOT82_1215Dihydropteridine reductase. (89 aa)
AOT82_1217Alcohol dehydrogenase class III; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
AOT82_1228Radical SAM domain-containing protein. (335 aa)
AOT82_1279Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (331 aa)
AOT82_1333-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (542 aa)
AOT82_1360methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (270 aa)
AOT82_1408isovaleryl-CoA dehydrogenase. (395 aa)
AOT82_1409hydroxymethylglutaryl-CoA lyase. (306 aa)
AOT82_1410Biotin carboxylase. (705 aa)
AOT82_1411methylglutaconyl-CoA hydratase. (272 aa)
AOT82_1412acyl-CoA biotin-dependent carboxyltransferase. (536 aa)
AOT82_1424Putative hydrolase. (238 aa)
AOT82_143Hypothetical protein. (147 aa)
AOT82_1483acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (393 aa)
AOT82_1507Transcriptional regulator. (311 aa)
AOT82_1509Hypothetical protein. (487 aa)
AOT82_1511Hypothetical protein. (158 aa)
AOT82_1522Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
AOT82_1555Hypothetical protein. (242 aa)
AOT82_156Hypothetical protein. (81 aa)
AOT82_1567Hypothetical protein. (111 aa)
AOT82_157Exodeoxyribonuclease large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (510 aa)
AOT82_1581N-ethylmaleimide reductase. (368 aa)
AOT82_15872,4-dienoyl-CoA reductase. (711 aa)
AOT82_1609Exopolyphosphatase; Belongs to the GppA/Ppx family. (520 aa)
AOT82_1615D-amino acid dehydrogenase small subunit. (441 aa)
AOT82_1643isovaleryl-CoA dehydrogenase. (606 aa)
AOT82_16455-carboxymethyl-2-hydroxymuconate delta-isomerase. (124 aa)
AOT82_1673Nucleoside triphosphate pyrophosphohydrolase. (288 aa)
AOT82_1695Thioesterase. (162 aa)
pnpPolynucleotide phosphorylase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (700 aa)
AOT82_1760Putative amidase. (205 aa)
AOT82_1790Hydrolase. (349 aa)
AOT82_1795Hypothetical protein. (316 aa)
AOT82_180Transglycosylase. (401 aa)
AOT82_1815enoyl-CoA hydratase. (266 aa)
AOT82_1858Hypothetical protein. (310 aa)
AOT82_19174-hydroxyphenylacetate 3-monooxygenase coupling protein. (171 aa)
AOT82_1925Phosphatidylglycerophosphatase A; Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). (201 aa)
rppHHypothetical protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (173 aa)
AOT82_206Xanthine dehydrogenase accessory factor. (349 aa)
AOT82_2062Hypothetical protein. (541 aa)
AOT82_2066acyl-CoA thioesterase II. (300 aa)
AOT82_207N-ethylammeline chlorohydrolase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (476 aa)
AOT82_2072Carboxymethylenebutenolidase. (245 aa)
AOT82_208Ureidoglycolate hydrolase. (175 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (463 aa)
alcHypothetical protein; Belongs to the allantoicase family. (366 aa)
AOT82_2090Hypothetical protein. (304 aa)
ureAHypothetical protein; Belongs to the urease gamma subunit family. (100 aa)
ureCUrease subunit alpha; Belongs to the urease beta subunit family. (724 aa)
AOT82_2135Deoxyribonucleotide triphosphate pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (217 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (719 aa)
fadASmall (beta) subunit of the fatty acid-oxidizing multienzyme complex; Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed. (390 aa)
AOT82_2143Phenazine biosynthesis protein. (191 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (150 aa)
AOT82_2155Hypothetical protein. (144 aa)
rphRNase PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa)
AOT82_222Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. (1082 aa)
AOT82_223Bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase. (230 aa)
AOT82_2243Isomerase. (427 aa)
AOT82_2252Putative acyl-CoA dehydrogenase. (968 aa)
AOT82_2254Phosphopantothenate--cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (465 aa)
AOT82_2303Hypothetical protein. (249 aa)
AOT82_2327Hypothetical protein. (144 aa)
AOT82_2365Hypothetical protein. (242 aa)
katGCatalase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (790 aa)
AOT82_2383Endoribonuclease L-PSP. (126 aa)
AOT82_2394Putative esterase; Serine hydrolase involved in the detoxification of formaldehyde. (296 aa)
AOT82_2503Electron transfer flavoprotein subunit alpha. (310 aa)
AOT82_2543Carboxymethylenebutenolidase. (263 aa)
AOT82_2545Hydroperoxidase II; Serves to protect cells from the toxic effects of hydrogen peroxide. (695 aa)
AOT82_2546Zn-dependent hydrolase, including glyoxylase. (262 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (154 aa)
AOT82_2577ferredoxin--NADP reductase. (275 aa)
AOT82_2591Nicotinate-nucleotide pyrophosphorylase; Belongs to the NadC/ModD family. (286 aa)
AOT82_2620Hypothetical protein. (226 aa)
surEStationary phase survival protein SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (269 aa)
AOT82_2671Hypothetical protein. (459 aa)
AOT82_276acyl-CoA dehydrogenase. (421 aa)
AOT82_277Hypothetical protein. (414 aa)
csrACarbon storage regulator; A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress, the stringent response and the catabolite repression systems. Usually binds in the 5'-UTR; binding at or near the Shine-Dalgarno sequence prevents ribosome-binding, repressing translation, binding elsewhere in the 5'-UTR can activate translation and/or stabilize the mRNA. Its function is antagonized by small RNA(s). (81 aa)
AOT82_2790Phospholipase/carboxylesterase. (223 aa)
AOT82_2798Exopolyphosphatase. (448 aa)
AOT82_294Hydrolase/acyltransferase. (349 aa)
AOT82_295Rubredoxin. (54 aa)
AOT82_309Gamma-glutamyltranspeptidase precursor. (645 aa)
AOT82_318Glutathione S-transferase. (216 aa)
AOT82_3222-keto-4-pentenoatehydratase/2-oxohepta-3-ene-1, 7-dioic acid hydratase. (429 aa)
AOT82_325Hypothetical protein. (371 aa)
AOT82_326Biopterin-dependent aromatic amino acid hydroxylase family protein. (313 aa)
AOT82_34Putative CoA-transferase, subunit A. (237 aa)
AOT82_347isovaleryl-CoA dehydrogenase. (384 aa)
AOT82_348enoyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (258 aa)
AOT82_349Putative 3-hydroxybutyryl-CoA dehydrogenase. (528 aa)
AOT82_35Putative CoA-transferase subunit B. (209 aa)
AOT82_350Putative acyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (400 aa)
AOT82_352Thioesterase. (159 aa)
AOT82_358Hypothetical protein. (150 aa)
AOT82_402Hypothetical protein. (421 aa)
AOT82_403RelE. (86 aa)
AOT82_452Glutamate dehydrogenase. (1614 aa)
AOT82_47Hypothetical protein. (85 aa)
gloBPutative hydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (259 aa)
AOT82_510isovaleryl-CoA dehydrogenase. (597 aa)
AOT82_53Sodium/proline symporter (proline permease); Catalyzes the sodium-dependent uptake of extracellular L- proline; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (499 aa)
ilvAThreonine deaminase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (517 aa)
AOT82_544Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (384 aa)
AOT82_580Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (290 aa)
AOT82_5903-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (313 aa)
AOT82_5913-hydroxyisobutyryl-CoA hydrolase. (383 aa)
AOT82_593Carnitine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (260 aa)
AOT82_594isovaleryl-CoA dehydrogenase. (386 aa)
AOT82_595NAD-dependent aldehyde dehydrogenase. (494 aa)
AOT82_603Hypothetical protein; Belongs to the aldehyde dehydrogenase family. (494 aa)
AOT82_606Putative NADP-dependent oxidoreductase. (349 aa)
AOT82_607Intracellular protease/amidase. (225 aa)
AOT82_70ferredoxin--NADP reductase. (257 aa)
AOT82_718Hypothetical protein. (147 aa)
AOT82_721Putative fatty acid oxidation complex alpha subunit; Belongs to the enoyl-CoA hydratase/isomerase family. (729 aa)
AOT82_722Small (beta) subunit of the fatty acid-oxidizing multienzyme complex; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
AOT82_723isovaleryl-CoA dehydrogenase. (383 aa)
AOT82_733Putative oxidoreductase. (260 aa)
AOT82_734NADP-dependent oxidoreductase. (335 aa)
AOT82_744NADH pyrophosphatase. (314 aa)
AOT82_7794-aminobutyrate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (419 aa)
AOT82_785acyl-CoA dehydrogenase domain-containingprotein. (394 aa)
AOT82_80Deoxyguanosinetriphosphate triphosphohydrolase-like protein. (472 aa)
gcvTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine. (393 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (965 aa)
AOT82_84D-amino acid dehydrogenase small subunit. (415 aa)
AOT82_864Putative hydrolase. (270 aa)
AOT82_865Carnitine racemase; Belongs to the enoyl-CoA hydratase/isomerase family. (265 aa)
AOT82_867Aconitate hydratase 2 (citrate hydro-lyase 2); Belongs to the aconitase/IPM isomerase family. (867 aa)
AOT82_873N-ethylmaleimide reductase. (379 aa)
Your Current Organism:
Psychrobacter sp. AntiMn1
NCBI taxonomy Id: 1720344
Other names: P. sp. AntiMn-1, Psychrobacter sp. AntiMn-1
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