STRINGSTRING
pfkA pfkA ALL04121.1 ALL04121.1 ALL04127.1 ALL04127.1 gltX gltX ALL04148.1 ALL04148.1 ALL08609.1 ALL08609.1 ALL04196.1 ALL04196.1 ALL04210.1 ALL04210.1 ALL04226.1 ALL04226.1 ALL04228.1 ALL04228.1 pckA pckA ALL04347.1 ALL04347.1 ALL04348.1 ALL04348.1 ALL04349.1 ALL04349.1 ALL04350.1 ALL04350.1 ALL08620.1 ALL08620.1 ALL04394.1 ALL04394.1 glyA glyA ALL04434.1 ALL04434.1 ALL04442.1 ALL04442.1 ALL04454.1 ALL04454.1 ALL04456.1 ALL04456.1 ALL04457.1 ALL04457.1 ALL04462.1 ALL04462.1 ALL04470.1 ALL04470.1 thrB thrB ALL04472.1 ALL04472.1 ALL04474.1 ALL04474.1 ALL04488.1 ALL04488.1 ALL04530.1 ALL04530.1 ALL04531.1 ALL04531.1 ALL04539.1 ALL04539.1 ALL04540.1 ALL04540.1 ALL04544.1 ALL04544.1 asd asd ALL04625.1 ALL04625.1 ALL04649.1 ALL04649.1 dapB dapB ALL04696.1 ALL04696.1 hemA hemA hemC hemC ALL04773.1 ALL04773.1 hemL hemL ALL04833.1 ALL04833.1 pgk pgk dapA dapA ALL04882.1 ALL04882.1 pfkA-2 pfkA-2 ALL04887.1 ALL04887.1 ALL04888.1 ALL04888.1 ALL04895.1 ALL04895.1 ALL04896.1 ALL04896.1 ALL04912.1 ALL04912.1 sdhA sdhA ALL04914.1 ALL04914.1 ALL04944.1 ALL04944.1 ALL05029.1 ALL05029.1 ALL05030.1 ALL05030.1 ALL05043.1 ALL05043.1 ALL05044.1 ALL05044.1 ALL05046.1 ALL05046.1 ALL05047.1 ALL05047.1 ALL05048.1 ALL05048.1 ALL05090.1 ALL05090.1 sucC sucC ALL05133.1 ALL05133.1 ALL05138.1 ALL05138.1 ALL05156.1 ALL05156.1 fbp fbp ubiX ubiX ALL05238.1 ALL05238.1 ALL05262.1 ALL05262.1 ALL05271.1 ALL05271.1 ALL05286.1 ALL05286.1 ALL05287.1 ALL05287.1 ALL05495.1 ALL05495.1 ALL05528.1 ALL05528.1 ALL05644.1 ALL05644.1 serC serC ALL08713.1 ALL08713.1 ALL05658.1 ALL05658.1 ALL05659.1 ALL05659.1 ALL05661.1 ALL05661.1 ALL05672.1 ALL05672.1 ALL05687.1 ALL05687.1 pdxH pdxH gltA gltA folD folD ALL05947.1 ALL05947.1 ALL05987.1 ALL05987.1 ureA ureA ureB ureB ureC ureC ackA ackA ALL06251.1 ALL06251.1 ALL06255.1 ALL06255.1 gpmA gpmA ALL06427.1 ALL06427.1 ALL06475.1 ALL06475.1 tal tal ALL06501.1 ALL06501.1 gltD gltD ALL06508.1 ALL06508.1 ALL06557.1 ALL06557.1 ALL06617.1 ALL06617.1 ALL06646.1 ALL06646.1 ALL06648.1 ALL06648.1 ALL06649.1 ALL06649.1 ALL06736.1 ALL06736.1 ALL06763.1 ALL06763.1 glyA-2 glyA-2 ALL06925.1 ALL06925.1 ALL06972.1 ALL06972.1 ALL08853.1 ALL08853.1 ALL07056.1 ALL07056.1 ALL07059.1 ALL07059.1 ALL08856.1 ALL08856.1 pckA-2 pckA-2 ALL07118.1 ALL07118.1 ALL07120.1 ALL07120.1 lysA lysA ALL07124.1 ALL07124.1 ALL07125.1 ALL07125.1 ALL07134.1 ALL07134.1 mqo mqo ALL07140.1 ALL07140.1 ALL07212.1 ALL07212.1 ALL07233.1 ALL07233.1 ALL07326.1 ALL07326.1 ALL07360.1 ALL07360.1 ALL07412.1 ALL07412.1 ALL07413.1 ALL07413.1 zwf zwf pgl pgl tpiA tpiA ALL07490.1 ALL07490.1 fabV fabV ALL07556.1 ALL07556.1 ALL07557.1 ALL07557.1 ALL07580.1 ALL07580.1 ALL07628.1 ALL07628.1 ALL07662.1 ALL07662.1 ALL07741.1 ALL07741.1 accD accD ALL07867.1 ALL07867.1 gpmI gpmI serC-2 serC-2 ALL07922.1 ALL07922.1 ALL07944.1 ALL07944.1 ALL07951.1 ALL07951.1 ALL07983.1 ALL07983.1 ALL08022.1 ALL08022.1 ALL08025.1 ALL08025.1 ALL08026.1 ALL08026.1 ALL08030.1 ALL08030.1 mdh mdh ALL08042.1 ALL08042.1 ALL08107.1 ALL08107.1 eno eno sucD sucD ALL08158.1 ALL08158.1 ALL08174.1 ALL08174.1 ALL08224.1 ALL08224.1 accA accA ALL08250.1 ALL08250.1 ALL08265.1 ALL08265.1 ALL08285.1 ALL08285.1 comB comB ALL08341.1 ALL08341.1 pgi pgi ALL08398.1 ALL08398.1 ALL08405.1 ALL08405.1 ALL08446.1 ALL08446.1 sdhA-2 sdhA-2 ALL08448.1 ALL08448.1 dapF dapF ALL08476.1 ALL08476.1 ALL08486.1 ALL08486.1 pdhA pdhA fumC fumC ALL08576.1 ALL08576.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (327 aa)
ALL04121.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (466 aa)
ALL04127.1Phosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle. (863 aa)
gltXglutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (502 aa)
ALL04148.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
ALL08609.1Acetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (378 aa)
ALL04196.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (476 aa)
ALL04210.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (328 aa)
ALL04226.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (512 aa)
ALL04228.1Phosphosulfolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
pckAPhosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (534 aa)
ALL04347.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
ALL04348.1Ureidoglycolate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
ALL04349.1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
ALL04350.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
ALL08620.1Hypothetical protein; Catalyzes the synthesis of activated sulfate. (178 aa)
ALL04394.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (423 aa)
ALL04434.1Acylphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
ALL04442.1Malic enzyme; NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (771 aa)
ALL04454.1Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
ALL04456.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
ALL04457.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (158 aa)
ALL04462.1Phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (309 aa)
ALL04470.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (815 aa)
thrBHomoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (311 aa)
ALL04472.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
ALL04474.15,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (318 aa)
ALL04488.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
ALL04530.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (802 aa)
ALL04531.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
ALL04539.12-oxoglutarate dehydrogenase subunit E1; Derived by automated computational analysis using gene prediction method: Protein Homology. (930 aa)
ALL04540.12-oxoglutarate dehydrogenase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (406 aa)
ALL04544.1Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (330 aa)
ALL04625.1D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)
ALL04649.1methylmalonyl-CoA mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
dapB4-hydroxy-tetrahydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (246 aa)
ALL04696.1acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. (630 aa)
hemASerine carboxypeptidase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (408 aa)
hemCPorphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. (529 aa)
ALL04773.1Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (322 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa)
ALL04833.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (331 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (397 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (293 aa)
ALL04882.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
pfkA-26-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (328 aa)
ALL04887.1Threonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
ALL04888.1Biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (495 aa)
ALL04895.1Homogentisate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
ALL04896.1Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
ALL04912.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (638 aa)
ALL04914.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
ALL04944.1Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (473 aa)
ALL05029.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
ALL05030.1Catalyzes the oxidation of acetaldehyde, benzaldehyde, propionaldehyde and other aldehydes; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
ALL05043.1Nitrite reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (695 aa)
ALL05044.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (262 aa)
ALL05046.1Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. (234 aa)
ALL05047.1Sulfate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
ALL05048.1Sulfate adenylyltransferase; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (416 aa)
ALL05090.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (739 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (396 aa)
ALL05133.1Glyceraldehyde-3-phosphate dehydrogenase; Catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; involved in growth under gluconeogenic conditions and in glycolytic activity at high ATP concentrations in Corynebacterium; NAD and NADP dependent; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (482 aa)
ALL05138.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (462 aa)
ALL05156.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (728 aa)
fbpFructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (351 aa)
ubiXSulfatase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (188 aa)
ALL05238.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (425 aa)
ALL05262.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
ALL05271.15-hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (135 aa)
ALL05286.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
ALL05287.13-hexulose-6-phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
ALL05495.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
ALL05528.1Fructose-bisphosphate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ALL05644.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (222 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (354 aa)
ALL08713.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa)
ALL05658.1Diapophytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa)
ALL05659.1Homoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
ALL05661.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
ALL05672.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (208 aa)
ALL05687.13-hydroxybutyryl-CoA dehydrogenase; Converts (S)-3-hydroxybutanoyl-CoA to 3-acetoacetyl-CoA; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
pdxHPyridoxine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (216 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (428 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (293 aa)
ALL05947.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa)
ALL05987.1Converts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (446 aa)
ureAUrease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. (100 aa)
ureBUrease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family. (125 aa)
ureCUrease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. (616 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
ALL06251.1Phosphoketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (786 aa)
ALL06255.1Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (200 aa)
ALL06427.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
ALL06475.1Nitrilase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
talFructose-6-phosphate aldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 3B subfamily. (221 aa)
ALL06501.1Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1501 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
ALL06508.1Aldose epimerase; Converts alpha-aldose to the beta-anomer. (345 aa)
ALL06557.1Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
ALL06617.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
ALL06646.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (541 aa)
ALL06648.1Ketohydroxyglutarate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)
ALL06649.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
ALL06736.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
ALL06763.1Mandelate racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (424 aa)
ALL06925.15-hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (137 aa)
ALL06972.15-hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (136 aa)
ALL08853.15-hydroxyisourate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. (135 aa)
ALL07056.1Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (460 aa)
ALL07059.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetokinase family. (193 aa)
ALL08856.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (411 aa)
pckA-2Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (521 aa)
ALL07118.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
ALL07120.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
lysADiaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (385 aa)
ALL07124.1Aspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (437 aa)
ALL07125.1Phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa)
ALL07134.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (501 aa)
ALL07140.1Succinate-semialdehyde dehydrogenase; In Escherichia coli this enzyme appears to be an NAD+/NADP+-dependent succinate semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
ALL07212.1Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
ALL07233.1Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (299 aa)
ALL07326.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (472 aa)
ALL07360.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (270 aa)
ALL07412.1Chromosome partitioning protein ParA; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
ALL07413.16-phosphogluconate dehydrogenase; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (470 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (503 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (241 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa)
ALL07490.1methylmalonyl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (396 aa)
ALL07556.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
ALL07557.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
ALL07580.1Aldose epimerase; Converts alpha-aldose to the beta-anomer. (397 aa)
ALL07628.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
ALL07662.1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (452 aa)
ALL07741.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (359 aa)
accDAcetyl-coenzyme A carboxylase carboxyl transferase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (281 aa)
ALL07867.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (506 aa)
serC-23-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (367 aa)
ALL07922.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (461 aa)
ALL07944.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
ALL07951.1ROK family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
ALL07983.1Ribokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
ALL08022.12-hydroxyhepta-2,4-diene-1,7-dioate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
ALL08025.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
ALL08026.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
ALL08030.1Aminotransferase class III; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (398 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (312 aa)
ALL08042.12,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the transferase hexapeptide repeat family. (272 aa)
ALL08107.1CoB--CoM heterodisulfide reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (431 aa)
sucDsuccinate--CoA ligase; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (290 aa)
ALL08158.1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (758 aa)
ALL08174.1methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
ALL08224.1Ribose-phosphate pyrophosphokinase; Catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
accAacetyl-CoA carboxyl transferase; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa)
ALL08250.1Exopolyphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
ALL08265.16-phosphogluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
ALL08285.1Nitroreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
comB2-phosphosulfolactate phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ComB family. (238 aa)
ALL08341.1uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
pgiGlucose-6-phosphate isomerase; Functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis; catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate; member of PGI family; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (548 aa)
ALL08398.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
ALL08405.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (432 aa)
ALL08446.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
sdhA-2Part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology. (659 aa)
ALL08448.1Succinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (261 aa)
ALL08476.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
ALL08486.1Pyruvate dehydrogenase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (549 aa)
pdhAPyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (331 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (465 aa)
ALL08576.1Gluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FGGY kinase family. (490 aa)
Your Current Organism:
Pedobacter sp. PACM27299
NCBI taxonomy Id: 1727164
Other names: P. sp. PACM 27299, Pedobacter sp. PACM 27299
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