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| | mfd-2 | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1156 aa) |
| | hisS | histidine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa) |
| | KQN21459.1 | glutamyl-Q tRNA(Asp) synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (292 aa) |
| | KQN21460.1 | MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa) |
| | KQN21480.1 | tRNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa) |
| | KQN21505.1 | RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. (258 aa) |
| | rlmE | rRNA methyltransferase; Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit. (226 aa) |
| | rpoZ | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (114 aa) |
| | KQN21542.1 | Xylose isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (303 aa) |
| | polA | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (924 aa) |
| | KQN21556.1 | SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (425 aa) |
| | tsaD | tRNA threonylcarbamoyl adenosine modification protein TsaD; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. (342 aa) |
| | KQN21561.1 | Hypothetical protein; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (548 aa) |
| | KQN21567.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa) |
| | KQN22600.1 | Nucleotidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa) |
| | dnaE2-2 | DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1127 aa) |
| | KQN21576.1 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa) |
| | leuS | leucine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (837 aa) |
| | KQN21582.1 | DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa) |
| | rsmG | 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG; Specifically methylates the N7 position of guanine in position 527 of 16S rRNA. (206 aa) |
| | mnmG | tRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (611 aa) |
| | mnmE | tRNA modification GTPase TrmE; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (426 aa) |
| | KQN21589.1 | Cysteine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa) |
| | rho | Transcription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (418 aa) |
| | dnaQ | DNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (230 aa) |
| | KQN21616.1 | Single-stranded DNA-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa) |
| | gltX | glutamine--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (447 aa) |
| | lysK | lysine--tRNA ligase; Class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (524 aa) |
| | KQN21670.1 | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. (589 aa) |
| | KQN21689.1 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa) |
| | pheS | phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (371 aa) |
| | pheT | phenylalanine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (804 aa) |
| | ihfA | Integration host factor subunit alpha; This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control. Belongs to the bacterial histone-like protein family. (99 aa) |
| | KQN21703.1 | Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa) |
| | KQN21708.1 | DNA ligase-associated DEXH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa) |
| | KQN21709.1 | RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (506 aa) |
| | KQN21712.1 | 3'-5' exonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (206 aa) |
| | KQN21714.1 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (536 aa) |
| | rlmN | 23S rRNA (adenine(2503)-C2)-methyltransferase; Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs. m2A2503 modification seems to play a crucial role in the proofreading step occurring at the peptidyl transferase center and thus would serve to optimize ribosomal fidelity; Belongs to the radical SAM superfamily. RlmN family. (396 aa) |
| | KQN21734.1 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (372 aa) |
| | recF | Recombinase RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP. (374 aa) |
| | gyrB | DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (843 aa) |
| | KQN21749.1 | DNA polymerase III subunit epsilon; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa) |
| | topA | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (873 aa) |
| | KQN21762.1 | RNA polymerase subunit sigma; Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (189 aa) |
| | KQN22639.1 | rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa) |
| | KQN21774.1 | uracil-DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa) |
| | KQN21779.1 | Translation factor Sua5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. (334 aa) |
| | rnhB | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (212 aa) |
| | KQN22642.1 | Modification methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (380 aa) |
| | KQN21798.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (811 aa) |
| | mutS | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. (859 aa) |
| | queG | Epoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (383 aa) |
| | tadA | CMP deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (143 aa) |
| | xseA | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (468 aa) |
| | KQN21894.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa) |
| | KQN21905.1 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (440 aa) |
| | KQN22672.1 | HNH endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (106 aa) |
| | KQN22680.1 | RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (177 aa) |
| | KQN21971.1 | Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa) |
| | KQN21972.1 | Biotin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa) |
| | smc | Chromosome segregation protein; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1131 aa) |
| | KQN21977.1 | A/G-specific adenine glycosylase; Adenine glycosylase active on G-A mispairs. (343 aa) |
| | KQN21992.1 | ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (833 aa) |
| | ku | DNA repair protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (295 aa) |
| | KQN21997.1 | Excinuclease ABC subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology. (82 aa) |
| | mnmA | tRNA-specific 2-thiouridylase; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34. (374 aa) |
| | KQN22015.1 | DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa) |
| | KQN22017.1 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (248 aa) |
| | KQN22024.1 | 16S rRNA methyltransferase; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. (257 aa) |
| | ligA | Aromatic ring-opening dioxygenase LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (714 aa) |
| | KQN22036.1 | DNA repair protein RecN; May be involved in recombinational repair of damaged DNA. (554 aa) |
| | KQN22047.1 | Radical SAM protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa) |
| | rlmJ | Protein involved in catabolism of external DNA; Specifically methylates the adenine in position 2030 of 23S rRNA. (276 aa) |
| | KQN22117.1 | ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (76 aa) |
| | KQN22707.1 | Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the RNase T2 family. (239 aa) |
| | KQN22126.1 | Integration host factor subunit beta; Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. (93 aa) |
| | dinB | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (362 aa) |
| | parE | DNA topoisomerase IV subunit B; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. (667 aa) |
| | trmL | rRNA methyltransferase; Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S-adenosyl-L-methionine to the 2'-OH of the wobble nucleotide. (149 aa) |
| | KQN22185.1 | Phosphodiesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa) |
| | glyQ | glycine--tRNA ligase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa) |
| | glyS | glycine--tRNA ligase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. (738 aa) |
| | rnhA | Ribonuclease HI; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (158 aa) |
| | proS | proline--tRNA ligase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (511 aa) |
| | KQN22235.1 | RNA pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa) |
| | KQN22258.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa) |
| | KQN22263.1 | single-stranded-DNA-specific exonuclease RecJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa) |
| | KQN22264.1 | Oxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa) |
| | KQN22285.1 | DNA repair photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa) |
| | recA | DNA recombination/repair protein RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (357 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1428 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1393 aa) |
| | KQN22337.1 | AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa) |
| | radA | DNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (456 aa) |
| | xerC | Recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (316 aa) |
| | KQN22351.1 | NTP pyrophosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa) |
| | KQN22385.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa) |
| | KQN22404.1 | MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa) |
| | KQN22406.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (764 aa) |
| | gltX-2 | glutamate--tRNA ligase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (481 aa) |
| | lexA | LexA repressor; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (241 aa) |
| | mfd | DEAD/DEAH box helicase; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1032 aa) |
| | nusG | Antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (178 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (356 aa) |
| | parC | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. (749 aa) |
| | KQN22475.1 | Polynucleotide adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (397 aa) |
| | KQN22489.1 | Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (496 aa) |
| | valS | valine--tRNA ligase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (936 aa) |
| | cysS | cysteine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family. (488 aa) |
| | mutM | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (271 aa) |
| | dnaA | Chromosomal replication initiator DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (496 aa) |
| | trpS | tryptophan--tRNA ligase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family. (335 aa) |
| | KQN22561.1 | DNA mismatch repair protein MutS; Derived by automated computational analysis using gene prediction method: Protein Homology. (194 aa) |
| | rnpA | Ribonuclease P protein component; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (129 aa) |
| | KQN22572.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa) |
| | KQN18101.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa) |
| | KQN16447.1 | Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa) |
| | KQN16451.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa) |
| | KQN16468.1 | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa) |
| | KQN16474.1 | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa) |
| | KQN16475.1 | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa) |
| | KQN16480.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa) |
| | KQN16483.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (167 aa) |
| | KQN16484.1 | AAA family ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1086 aa) |
| | KQN16493.1 | Twitching motility protein PilT; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa) |
| | vapC | Transcriptional regulator; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (129 aa) |
| | KQN16504.1 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa) |
| | KQN16521.1 | Nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa) |
| | KQN16630.1 | RepA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa) |
| | KQN16631.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (390 aa) |
| | KQN16539.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (400 aa) |
| | dnaE2 | DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1087 aa) |
| | KQN16559.1 | Protein ImuB; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa) |
| | KQN16635.1 | Protein ImuA; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa) |
| | KQN16636.1 | Competence protein ComEA; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa) |
| | KQN16565.1 | Cytosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa) |
| | KQN16579.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa) |
| | KQN16597.1 | Hydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the hyi family. (260 aa) |
| | KQN15022.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa) |
| | KQN15030.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa) |
| | KQN15049.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (165 aa) |
| | ASE89_19325 | Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa) |
| | KQN16769.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1109 aa) |
| | KQN16763.1 | Plasmid replication initiator protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa) |
| | KQN17099.1 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa) |
| | KQN17397.1 | Conjugal transfer protein TraA; MobA/MobL family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (990 aa) |
| | KQN17380.1 | RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (197 aa) |
| | KQN17374.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa) |
| | KQN17372.1 | Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology. (187 aa) |
| | KQN17359.1 | Replication protein RepB; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa) |
| | KQN18317.1 | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa) |
| | KQN18315.1 | RepA family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa) |
| | KQN18314.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (313 aa) |
| | KQN18540.1 | DNA recombinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (365 aa) |
| | ASE89_18590 | TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa) |
| | KQN18867.1 | Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (371 aa) |
| | KQN18865.1 | Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa) |
| | ASE89_18535 | Recombinase domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa) |
| | KQN18878.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (277 aa) |
| | KQN18873.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (91 aa) |
| | KQN20389.1 | RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (160 aa) |
| | KQN20320.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (113 aa) |
| | KQN20271.1 | RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology. (168 aa) |
| | KQN20263.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa) |
| | KQN20232.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa) |
| | KQN20219.1 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. (398 aa) |
| | truA | Pseudouridine synthase; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs. (246 aa) |
| | fmt | methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (308 aa) |
| | recR | Recombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (198 aa) |
| | KQN20214.1 | Recombinase RmuC; Derived by automated computational analysis using gene prediction method: Protein Homology. (487 aa) |
| | KQN20213.1 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (265 aa) |
| | KQN20202.1 | RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (395 aa) |
| | rsmA | 16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (283 aa) |
| | KQN20199.1 | DNA polymerase III subunit chi; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa) |
| | KQN20193.1 | Chromosomal replication initiator DnaA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DnaA family. (214 aa) |
| | rnd | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. (391 aa) |
| | aspS | aspartate--tRNA(Asp/Asn) ligase; Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp/Asn); Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (608 aa) |
| | KQN20181.1 | tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family. (332 aa) |
| | KQN20173.1 | LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa) |
| | metG | methionine--tRNA ligase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 2B subfamily. (520 aa) |
| | KQN20171.1 | DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa) |
| | KQN20169.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (647 aa) |
| | KQN21088.1 | RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (171 aa) |
| | KQN21081.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa) |
| | rimO | Ribosomal protein S12 methylthiotransferase RimO; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. (442 aa) |
| | trmFO | tRNA (uracil-5-)-methyltransferase; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. (455 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (926 aa) |
| | KQN21043.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa) |
| | rnr | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (738 aa) |
| | KQN21033.1 | Hemolysin; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa) |
| | KQN21156.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0176 family. (331 aa) |
| | KQN20928.1 | DNA topoisomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa) |
| | KQN20905.1 | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa) |
| | KQN20892.1 | Cytosine deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | KQN20890.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (239 aa) |
| | KQN20830.1 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaE; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa) |
| | KQN20827.1 | Double-strand break repair protein AddB; Derived by automated computational analysis using gene prediction method: Protein Homology. (980 aa) |
| | KQN20826.1 | DNA helicase UvrD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the helicase family. UvrD subfamily. (1142 aa) |
| | KQN20817.1 | Resolvase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa) |
| | KQN20813.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (498 aa) |
| | KQN20806.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (693 aa) |
| | KQN20801.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (82 aa) |
| | KQN20800.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa) |
| | KQN20791.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa) |
| | KQN20789.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa) |
| | KQN20771.1 | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (115 aa) |
| | KQN11628.1 | DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1162 aa) |
| | mutL | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. (604 aa) |
| | KQN11645.1 | DNA adenine methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (335 aa) |
| | KQN11570.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa) |
| | KQN11565.1 | Terminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (608 aa) |
| | KQN12760.1 | RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (175 aa) |
| | KQN12735.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa) |
| | KQN14695.1 | Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa) |
| | KQN14686.1 | Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa) |
| | KQN14676.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (525 aa) |
| | KQN14675.1 | 16S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa) |
| | dnaG | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (620 aa) |
| | rpoD | RNA polymerase subunit sigma; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (675 aa) |
| | KQN14650.1 | Pseudouridine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudouridine synthase RsuA family. (180 aa) |
| | trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (241 aa) |
| | rimM | Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (166 aa) |
| | KQN14645.1 | 2-methylthioadenine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa) |
| | KQN14633.1 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa) |
| | KQN14622.1 | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (315 aa) |
| | rpoH | RNA polymerase subunit sigma-70; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (300 aa) |
| | dnaX | DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (567 aa) |
| | KQN14578.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (111 aa) |
| | KQN14562.1 | Holliday junction resolvase; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF HJR family. (155 aa) |
| | miaA | tRNA dimethylallyltransferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (313 aa) |
| | KQN14820.1 | Dimethylallyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa) |
| | KQN14541.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa) |
| | KQN14534.1 | Exodeoxyribonuclease III; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa) |
| | KQN14528.1 | RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (217 aa) |
| | argS | arginine--tRNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa) |
| | rsmH | Ribosomal RNA small subunit methyltransferase H; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (318 aa) |
| | alaS | alanine--tRNA ligase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (880 aa) |
| | apaG | Co2+/Mg2+ efflux protein ApaG; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa) |
| | recO | DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination. (243 aa) |
| | uvrC | Excinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (641 aa) |
| | dnaJ | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (378 aa) |
| | KQN14457.1 | Vgr related protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa) |
| | rph | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (238 aa) |
| | rsmI | 16S rRNA methyltransferase; Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA. (285 aa) |
| | KQN14447.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0102 family. (132 aa) |
| | KQN14444.1 | Recombinase XerC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (299 aa) |
| | priA | Primosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (723 aa) |
| | KQN14434.1 | 6-O-methylguanine DNA methyltransferase; Regulates genes involved in the repair of alkylated DNA; repairs DNA containing 6-O-methylguanine; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa) |
| | uvrB | Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (732 aa) |
| | rnc | Ribonuclease III; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (220 aa) |
| | rbfA | Ribosome-binding factor A; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (129 aa) |
| | tdk | Thymidine kinase; Catalyzes the formation of thymidine 5'-phosphate from thymidine; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa) |
| | truB | Pseudouridine synthase; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. (302 aa) |
| | KQN14792.1 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (818 aa) |
| | ileS | isoleucine--tRNA ligase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. (962 aa) |
| | KQN14788.1 | Multidrug transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa) |
| | KQN14372.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (529 aa) |
| | xseB | Exodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (79 aa) |
| | tgt | Queuine tRNA-ribosyltransferase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form t [...] (381 aa) |
| | uvrA | ABC-ATPase UvrA; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (964 aa) |
| | KQN14341.1 | GIY-YIG nuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa) |
| | KQN14339.1 | ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology. (363 aa) |
| | nth | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (229 aa) |
| | KQN14303.1 | Integrase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 'phage' integrase family. (368 aa) |
| | KQN14277.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa) |
| | KQN14270.1 | DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa) |
| | KQN14268.1 | DNA repair protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa) |
| | KQN14267.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S24 family. (141 aa) |
| | KQN14261.1 | Hydroxypyruvate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa) |
| | KQN14245.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (588 aa) |
| | KQN14219.1 | tRNA threonylcarbamoyladenosine biosynthesis protein TsaB; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa) |
| | miaB | (dimethylallyl)adenosine tRNA methylthiotransferase; Catalyzes the methylthiolation of N6-(dimethylallyl)adenosine (i(6)A), leading to the formation of 2-methylthio-N6- (dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine. (423 aa) |
| | ybeY | rRNA maturation RNase YbeY; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (169 aa) |
| | trmB | tRNA (guanine-N7)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. (226 aa) |
| | KQN14189.1 | Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (639 aa) |
| | KQN14178.1 | Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (351 aa) |
| | thrS | threonine--tRNA ligase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (663 aa) |
| | KQN14151.1 | DEAD/DEAH box helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. (477 aa) |
| | KQN14088.1 | ATP-dependent endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (667 aa) |
| | KQN14080.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa) |
| | KQN14070.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (445 aa) |
| | KQN14060.1 | Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa) |
| | KQN14059.1 | BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (95 aa) |
| | KQN15075.1 | Magnesium protoporphyrin O-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa) |
| | nusB | Antitermination protein NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (151 aa) |
| | KQN14048.1 | DNA methylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the N(4)/N(6)-methyltransferase family. (491 aa) |
| | KQN14045.1 | Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa) |
| | KQN14026.1 | DNA polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa) |
| | rlmH | 50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. (140 aa) |
| | tilS | tRNA(Ile)-lysidine synthetase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (339 aa) |
| | ruvB | ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (341 aa) |
| | ruvA | ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (199 aa) |
| | ruvC | Holliday junction resolvase; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (168 aa) |
| | KQN14721.1 | DNA-deoxyinosine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa) |
| | KQN13993.1 | Deoxyribodipyrimidine photolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa) |
| | rne | Ribonuclease; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (982 aa) |
| | KQN13920.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa) |
| | serS | serine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (426 aa) |
| | tyrS | tyrosine--tRNA ligase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (407 aa) |
