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KQN58933.1 KQN58933.1 mqo-3 mqo-3 KQN59354.1 KQN59354.1 KQN59347.1 KQN59347.1 KQN59258.1 KQN59258.1 mqo-2 mqo-2 KQN59207.1 KQN59207.1 KQN59155.1 KQN59155.1 KQN59148.1 KQN59148.1 gltA gltA sdhC sdhC sdhD sdhD sdhA sdhA sdhB sdhB KQN59076.1 KQN59076.1 lpdA-2 lpdA-2 sucC sucC sucD sucD paaC paaC KQN65569.1 KQN65569.1 KQN65542.1 KQN65542.1 ilvA-2 ilvA-2 fumC fumC serC serC mmsA-2 mmsA-2 KQN57402.1 KQN57402.1 KQN57380.1 KQN57380.1 accC accC KQN57376.1 KQN57376.1 KQN57375.1 KQN57375.1 aceA aceA KQN58979.1 KQN58979.1 KQN58978.1 KQN58978.1 gnd gnd zwf-3 zwf-3 KQN58934.1 KQN58934.1 KQN59748.1 KQN59748.1 KQN59744.1 KQN59744.1 KQN60219.1 KQN60219.1 KQN60132.1 KQN60132.1 pyk-2 pyk-2 KQN60067.1 KQN60067.1 fabV fabV KQN59901.1 KQN59901.1 KQN59899.1 KQN59899.1 KQN59898.1 KQN59898.1 mmsA mmsA KQN61731.1 KQN61731.1 pyk pyk KQN61721.1 KQN61721.1 KQN61644.1 KQN61644.1 KQN61613.1 KQN61613.1 KQN61487.1 KQN61487.1 KQN61450.1 KQN61450.1 glcB glcB cysK cysK KQN59580.1 KQN59580.1 acs-2 acs-2 lpdA-3 lpdA-3 KQN58280.1 KQN58280.1 glcB-2 glcB-2 aceE aceE aceF aceF fdhA fdhA glyA-2 glyA-2 KQN58377.1 KQN58377.1 lcdH lcdH KQN58390.1 KQN58390.1 pckA pckA KQN58484.1 KQN58484.1 accD accD KQN57484.1 KQN57484.1 tcuA tcuA KQN57515.1 KQN57515.1 KQN61324.1 KQN61324.1 KQN61323.1 KQN61323.1 acnB acnB folD folD vapC vapC KQN62149.1 KQN62149.1 KQN62067.1 KQN62067.1 arsC arsC fghA fghA KQN67318.1 KQN67318.1 eno eno accA accA KQN67289.1 KQN67289.1 ppc ppc KQN67193.1 KQN67193.1 pgl pgl zwf-2 zwf-2 KQN67190.1 KQN67190.1 glk glk edd edd gapA-2 gapA-2 arcC arcC gcvH-2 gcvH-2 gcvP-2 gcvP-2 KQN67155.1 KQN67155.1 gcvT gcvT cysE cysE KQN66992.1 KQN66992.1 KQN66983.1 KQN66983.1 mqo mqo prs prs glyA glyA mdh mdh pgi pgi acs acs tpiA tpiA KQN66756.1 KQN66756.1 KQN66719.1 KQN66719.1 KQN66702.1 KQN66702.1 KQN66621.1 KQN66621.1 fba fba pgk pgk tkt tkt metF metF fbp fbp gpmI gpmI KQN66446.1 KQN66446.1 KQN66404.1 KQN66404.1 ilvA ilvA rpiA rpiA KQN66381.1 KQN66381.1 gcvP gcvP gcvH gcvH gcvT-2 gcvT-2 KQN66256.1 KQN66256.1 oadA oadA KQN66180.1 KQN66180.1 hexR hexR zwf zwf lpdA lpdA katE katE KQN66041.1 KQN66041.1 KQN66036.1 KQN66036.1 acnA acnA fadB fadB KQN57578.1 KQN57578.1 tal tal KQN57653.1 KQN57653.1 KQN57655.1 KQN57655.1 KQN57656.1 KQN57656.1 KQN57675.1 KQN57675.1 KQN57677.1 KQN57677.1 KQN57307.1 KQN57307.1 KQN57315.1 KQN57315.1 fdnG fdnG fdxH fdxH KQN57318.1 KQN57318.1 KQN57374.1 KQN57374.1
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
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experimentally determined
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gene neighborhood
gene fusions
gene co-occurrence
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co-expression
protein homology
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KQN58933.1Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
mqo-3Malate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (545 aa)
KQN59354.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
KQN59347.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (174 aa)
KQN59258.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
mqo-2Malate:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
KQN59207.1Catalase; Has an organic peroxide-dependent peroxidase activity. Belongs to the catalase family. (350 aa)
KQN59155.1Gluconolactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
KQN59148.13-hydroxybutyryl-CoA epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the enoyl-CoA hydratase/isomerase family. (694 aa)
gltAType II enzyme; in Escherichia coli this enzyme forms a trimer of dimers which is allosterically inhibited by NADH and competitively inhibited by alpha-ketoglutarate; allosteric inhibition is lost when Cys206 is chemically modified which also affects hexamer formation; forms oxaloacetate and acetyl-CoA and water from citrate and coenzyme A; functions in TCA cycle, glyoxylate cycle and respiration; enzyme from Helicobacter pylori is not inhibited by NADH; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (429 aa)
sdhCSuccinate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
sdhDSuccinate dehydrogenase; Membrane-anchoring subunit of succinate dehydrogenase (SDH). (122 aa)
sdhAPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (590 aa)
sdhBPart of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
KQN59076.12-oxoglutarate dehydrogenase subunit E1; Derived by automated computational analysis using gene prediction method: Protein Homology. (943 aa)
lpdA-2E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
sucCsuccinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (388 aa)
sucDsuccinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (294 aa)
paaC3-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (505 aa)
KQN65569.1Gluconokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
KQN65542.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa)
ilvA-2Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa)
fumCFumarate hydratase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
mmsA-2Methylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
KQN57402.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (425 aa)
KQN57380.1acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (153 aa)
accCacetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (451 aa)
KQN57376.1ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
KQN57375.1Pyruvate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
aceAIsocitrate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
KQN58979.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
KQN58978.1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
gnd6-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
zwf-3Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (501 aa)
KQN58934.1Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (741 aa)
KQN59748.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (325 aa)
KQN59744.1Lipid-transfer protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
KQN60219.1Beta-agarase; Derived by automated computational analysis using gene prediction method: Protein Homology. (744 aa)
KQN60132.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (84 aa)
pyk-2Pyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
KQN60067.1Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)
fabVtrans-2-enoyl-CoA reductase; Involved in the final reduction of the elongation cycle of fatty acid synthesis (FAS II). Catalyzes the reduction of a carbon- carbon double bond in an enoyl moiety that is covalently linked to an acyl carrier protein (ACP); Belongs to the TER reductase family. (403 aa)
KQN59901.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (392 aa)
KQN59899.1Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
KQN59898.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
mmsAMethylmalonate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (508 aa)
KQN61731.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
pykPyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (471 aa)
KQN61721.1Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (424 aa)
KQN61644.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
KQN61613.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
KQN61487.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
KQN61450.1RpiR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
glcBMalate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (723 aa)
cysKCysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (324 aa)
KQN59580.13-hydroxybutyryl-CoA dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
acs-2Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa)
lpdA-3Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
KQN58280.1Ribulose phosphate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (224 aa)
glcB-2Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (725 aa)
aceEPyruvate dehydrogenase; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (881 aa)
aceFDihydrolipoamide acetyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (546 aa)
fdhAAldehyde dismutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
glyA-2Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
KQN58377.1(Fe-S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (650 aa)
lcdH3-hydroxybutyryl-CoA dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-carnitine to 3- dehydrocarnitine. (321 aa)
KQN58390.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
pckAPhosphoenolpyruvate carboxykinase [ATP]; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family. (513 aa)
KQN58484.1Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (297 aa)
KQN57484.13-carboxymuconate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
tcuACatalyzes the oxidation of tricarballylate to cis-aconitate; FAD-dependent; required for the utilization of tricarballylate as a carbon and energy source by S. enterica; Derived by automated computational analysis using gene prediction method: Protein Homology. (484 aa)
KQN57515.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (791 aa)
KQN61324.1acetyl-CoA acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
KQN61323.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
acnBAconitate hydratase B; Catalyzes the conversion of citrate to isocitrate and the conversion of 2-methylaconitate to 2-methylisocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aconitase/IPM isomerase family. (869 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (284 aa)
vapCPlasmid maintenance protein; Toxic component of a toxin-antitoxin (TA) system. An RNase. Belongs to the PINc/VapC protein family. (136 aa)
KQN62149.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
KQN62067.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
arsCArsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
fghAS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (284 aa)
KQN67318.1Catalyzes the formation of S-formylglutathione from S-(hydroxymethyl)glutathione; also catalyzes the formation of aldehyde or ketone from alcohols; Derived by automated computational analysis using gene prediction method: Protein Homology. (370 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (429 aa)
accAacetyl-CoA carboxylase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (315 aa)
KQN67289.1ArsC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (118 aa)
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (875 aa)
KQN67193.1Keto-deoxy-phosphogluconate aldolase; Catalyzes the formation of pyruvate and glyoxylate from 4-hydroxy-2-oxoglutarate; or pyruvate and D-glyceraldehyde 3-phosphate from 2-dehydro-3-deoxy-D-glyconate 6-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (237 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (489 aa)
KQN67190.1Transcriptional regulator; Represses the expression of the zwf, eda, glp and gap; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)
glkGlucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (320 aa)
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (608 aa)
gapA-2Glyceraldehyde-3-phosphate dehydrogenase; Required for glycolysis; catalyzes the formation of 3-phospho-D-glyceroyl phosphate from D-glyceraldehyde 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (333 aa)
arcCCarbamate kinase; Reversible synthesis of carbamate and ATP from carbamoyl phosphate and ADP; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
gcvH-2Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvP-2Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (951 aa)
KQN67155.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
gcvTGlycine cleavage system protein T; Catalyzes the transfer of a methylene carbon from the methylamine-loaded GcvH protein to tetrahydrofolate, causing the release of ammonia and the generation of reduced GcvH protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
cysESerine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (261 aa)
KQN66992.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (695 aa)
KQN66983.1Glycerate dehydrogenase; Catalyzes the reduction of hydroxypyruvate to form D-glycerate, using NADH as an electron donor; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (321 aa)
mqoMalate:quinone oxidoreductase; Malate dehydrogenase; catalyzes the oxidation of malate to oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (502 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (313 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (417 aa)
mdhMalate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (309 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (554 aa)
acsAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (644 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (251 aa)
KQN66756.1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
KQN66719.1LD-carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
KQN66702.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
KQN66621.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
fbaFructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (387 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (665 aa)
metF5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. (281 aa)
fbpFructose 1,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (336 aa)
gpmI2,3-bisphosphoglycerate-independent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (511 aa)
KQN66446.1Malate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
KQN66404.1Phosphorylcholine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (504 aa)
rpiARibose 5-phosphate isomerase; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (224 aa)
KQN66381.1D-3-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (409 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (957 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (127 aa)
gcvT-2Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (360 aa)
KQN66256.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
oadAPyruvate carboxylase subunit B; Catalyzes the formation of oxaloacetate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (602 aa)
KQN66180.1Pyruvate carboxylase subunit A; Catalyzes the ATP-dependent carboxylation of a covalently attached biotin and the transfer of the carboxyl group to pyruvate forming oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (471 aa)
hexRTranscriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (480 aa)
lpdACatalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
katEHydroperoxidase; Serves to protect cells from the toxic effects of hydrogen peroxide. (711 aa)
KQN66041.1Aldehyde-activating protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
KQN66036.1acetyl-CoA hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
acnAAconitate hydratase; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (913 aa)
fadBMultifunctional fatty acid oxidation complex subunit alpha; Involved in the aerobic and anaerobic degradation of long- chain fatty acids via beta-oxidation cycle. Catalyzes the formation of 3-oxoacyl-CoA from enoyl-CoA via L-3-hydroxyacyl-CoA. It can also use D-3-hydroxyacyl-CoA and cis-3-enoyl-CoA as substrate. In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. (715 aa)
KQN57578.1Glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (487 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (308 aa)
KQN57653.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (160 aa)
KQN57655.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (956 aa)
KQN57656.1Formate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (67 aa)
KQN57675.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)
KQN57677.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (397 aa)
KQN57307.1Catalase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the catalase family. (479 aa)
KQN57315.1Sulfate ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
fdnGFormate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family. (809 aa)
fdxHFormate dehydrogenase; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers. (316 aa)
KQN57318.1Formate dehydrogenase; Cytochrome b556(FDO) component; heme containing; Derived by automated computational analysis using gene prediction method: Protein Homology. (218 aa)
KQN57374.1Acetoin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
Your Current Organism:
Pseudomonas sp. Leaf58
NCBI taxonomy Id: 1736226
Other names: P. sp. Leaf58
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