(16 nodes) Terpenoid biosynthetic process network (Sphingomonas sp. Leaf198)

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second shell of interactors

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proteins of unknown 3D structure

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protein homology

Your Input:
	dxs-2	1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
	dxs	1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (640 aa)
	dxr	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (385 aa)
	KQS48120.1	Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
	KQS48118.1	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
	ispG	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (378 aa)
	KQS49141.1	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
	ispH-2	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (314 aa)
	KQS51474.1	Squalene--hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (645 aa)
	KQS51889.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
	KQS51473.1	Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
	ispDF	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF). (382 aa)
	KQS50886.1	CrtK protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
	ispE	4-diphosphocytidyl-2C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (314 aa)
	ispH	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (318 aa)
	KQS50842.1	tspO/MBR family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)

Your Current Organism:

Sphingomonas sp. Leaf198

NCBI taxonomy Id: 1736299
Other names: S. sp. Leaf198

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KQS48118.1	KQS48120.1	ASG20_13365	ASG20_13375	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
KQS48118.1	KQS49141.1	ASG20_13365	ASG20_08755	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.733
KQS48118.1	KQS50842.1	ASG20_13365	ASG20_01615	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	tspO/MBR family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.445
KQS48118.1	KQS50886.1	ASG20_13365	ASG20_01950	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	CrtK protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.486
KQS48118.1	KQS51473.1	ASG20_13365	ASG20_05500	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.985
KQS48118.1	KQS51889.1	ASG20_13365	ASG20_05505	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.722
KQS48120.1	KQS48118.1	ASG20_13375	ASG20_13365	Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.998
KQS48120.1	KQS51474.1	ASG20_13375	ASG20_05510	Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Squalene--hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.646
KQS48120.1	KQS51889.1	ASG20_13375	ASG20_05505	Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.722
KQS48120.1	ispDF	ASG20_13375	ASG20_04230	Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).	0.424
KQS49141.1	KQS48118.1	ASG20_08755	ASG20_13365	Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.733
KQS50842.1	KQS48118.1	ASG20_01615	ASG20_13365	tspO/MBR family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.445
KQS50886.1	KQS48118.1	ASG20_01950	ASG20_13365	CrtK protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.486
KQS51473.1	KQS48118.1	ASG20_05500	ASG20_13365	Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phytoene dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.985
KQS51473.1	KQS51474.1	ASG20_05500	ASG20_05510	Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology.	Squalene--hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.969
KQS51473.1	KQS51889.1	ASG20_05500	ASG20_05505	Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.988
KQS51473.1	ispDF	ASG20_05500	ASG20_04230	Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).	0.424
KQS51474.1	KQS48120.1	ASG20_05510	ASG20_13375	Squalene--hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.646
KQS51474.1	KQS51473.1	ASG20_05510	ASG20_05500	Squalene--hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.969
KQS51474.1	KQS51889.1	ASG20_05510	ASG20_05505	Squalene--hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.971