STRINGSTRING
FSZ17_12065 FSZ17_12065 FSZ17_15840 FSZ17_15840 pyrR pyrR pyrB pyrB pyrC pyrC carA carA carB carB pyrK pyrK pyrD pyrD pyrF pyrF pyrE pyrE pyrH pyrH FSZ17_10955 FSZ17_10955 FSZ17_11295 FSZ17_11295 FSZ17_11860 FSZ17_11860 FSZ17_11900 FSZ17_11900 FSZ17_04940 FSZ17_04940 FSZ17_01460 FSZ17_01460 FSZ17_01730 FSZ17_01730 FSZ17_01785 FSZ17_01785 FSZ17_02085 FSZ17_02085 groS groS FSZ17_03405 FSZ17_03405 FSZ17_21085 FSZ17_21085 FSZ17_12980 FSZ17_12980 GCA_001439625_01446 GCA_001439625_01446 FSZ17_06825 FSZ17_06825 tmk tmk mazG mazG FSZ17_13860 FSZ17_13860 FSZ17_13865 FSZ17_13865 deoD deoD thyA thyA ndk ndk cmk cmk FSZ17_15315 FSZ17_15315 FSZ17_15320 FSZ17_15320 FSZ17_00095 FSZ17_00095 FSZ17_16265 FSZ17_16265 FSZ17_16415 FSZ17_16415 udk udk FSZ17_16580 FSZ17_16580 tgt tgt nrdR nrdR FSZ17_22770 FSZ17_22770 FSZ17_22580 FSZ17_22580 pyrG pyrG tdk tdk upp upp FSZ17_21565 FSZ17_21565 FSZ17_18990 FSZ17_18990 FSZ17_20385 FSZ17_20385 FSZ17_20575 FSZ17_20575 FSZ17_08500 FSZ17_08500 carB-2 carB-2 FSZ17_08120 FSZ17_08120 FSZ17_07370 FSZ17_07370 FSZ17_07320 FSZ17_07320 codA codA FSZ17_07190 FSZ17_07190 FSZ17_06085 FSZ17_06085 psuG psuG FSZ17_05550 FSZ17_05550 FSZ17_02245 FSZ17_02245 FSZ17_02605 FSZ17_02605 FSZ17_03110 FSZ17_03110 FSZ17_04285 FSZ17_04285
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FSZ17_12065Unannotated protein; Belongs to the major facilitator superfamily. (521 aa)
FSZ17_15840Unannotated protein; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (852 aa)
pyrRUnannotated protein; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (190 aa)
pyrBUnannotated protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (312 aa)
pyrCUnannotated protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (428 aa)
carAUnannotated protein; Belongs to the CarA family. (361 aa)
carBUnannotated protein; Belongs to the CarB family. (1070 aa)
pyrKUnannotated protein; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (259 aa)
pyrDUnannotated protein; Catalyzes the conversion of dihydroorotate to orotate. (303 aa)
pyrFUnannotated protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (238 aa)
pyrEUnannotated protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (212 aa)
pyrHUnannotated protein; Catalyzes the reversible phosphorylation of UMP to UDP. (241 aa)
FSZ17_10955Unannotated protein. (196 aa)
FSZ17_11295Unannotated protein. (264 aa)
FSZ17_11860Unannotated protein. (330 aa)
FSZ17_11900Unannotated protein; Belongs to the 5'-nucleotidase family. (374 aa)
FSZ17_04940Unannotated protein. (390 aa)
FSZ17_01460Unannotated protein. (394 aa)
FSZ17_01730Unannotated protein. (389 aa)
FSZ17_01785Unannotated protein. (283 aa)
FSZ17_02085Unannotated protein; Belongs to the 5'-nucleotidase family. (529 aa)
groSUnannotated protein; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (94 aa)
FSZ17_03405Unannotated protein. (590 aa)
FSZ17_21085Unannotated protein; Belongs to the LOG family. (188 aa)
FSZ17_12980Unannotated protein; Belongs to the Nudix hydrolase family. (133 aa)
GCA_001439625_01446Unannotated protein. (127 aa)
FSZ17_06825Unannotated protein. (161 aa)
tmkUnannotated protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (212 aa)
mazGUnannotated protein. (492 aa)
FSZ17_13860Unannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (762 aa)
FSZ17_13865Unannotated protein; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (348 aa)
deoDUnannotated protein. (234 aa)
thyAUnannotated protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
ndkUnannotated protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (148 aa)
cmkUnannotated protein. (224 aa)
FSZ17_15315Unannotated protein. (434 aa)
FSZ17_15320Unannotated protein; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. (274 aa)
FSZ17_00095Unannotated protein. (222 aa)
FSZ17_16265Unannotated protein; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (132 aa)
FSZ17_16415Unannotated protein. (143 aa)
udkUnannotated protein. (211 aa)
FSZ17_16580Unannotated protein. (63 aa)
tgtUnannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...] (379 aa)
nrdRUnannotated protein; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (153 aa)
FSZ17_22770Unannotated protein. (802 aa)
FSZ17_22580Unannotated protein. (402 aa)
pyrGUnannotated protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (534 aa)
tdkUnannotated protein. (205 aa)
uppUnannotated protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (209 aa)
FSZ17_21565Unannotated protein; Belongs to the 5'-nucleotidase family. (625 aa)
FSZ17_18990Unannotated protein; Belongs to the Nudix hydrolase family. (163 aa)
FSZ17_20385Unannotated protein. (234 aa)
FSZ17_20575Unannotated protein; Belongs to the 5'-nucleotidase family. (597 aa)
FSZ17_08500Unannotated protein. (428 aa)
carB-2Unannotated protein. (1035 aa)
FSZ17_08120Unannotated protein. (149 aa)
FSZ17_07370Unannotated protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (240 aa)
FSZ17_07320Unannotated protein. (613 aa)
codAUnannotated protein. (414 aa)
FSZ17_07190Unannotated protein. (451 aa)
FSZ17_06085Unannotated protein. (284 aa)
psuGUnannotated protein; Catalyzes the reversible cleavage of pseudouridine 5'- phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway; Belongs to the pseudouridine-5'-phosphate glycosidase family. (303 aa)
FSZ17_05550Unannotated protein. (365 aa)
FSZ17_02245Unannotated protein. (456 aa)
FSZ17_02605Unannotated protein. (390 aa)
FSZ17_03110Unannotated protein. (159 aa)
FSZ17_04285Unannotated protein. (116 aa)
Your Current Organism:
Bacillus sp. FJAT25496
NCBI taxonomy Id: 1742359
Other names: B. sp. FJAT-25496, Bacillus sp. FJAT-25496
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