STRINGSTRING
gcvH gcvH ANI98730.1 ANI98730.1 ANI98790.1 ANI98790.1 ANI98791.1 ANI98791.1 rppH rppH xseA xseA ANI98894.1 ANI98894.1 ANI98920.1 ANI98920.1 ANI98953.1 ANI98953.1 ANI98954.1 ANI98954.1 rne rne ANI99023.1 ANI99023.1 ANI99052.1 ANI99052.1 ANI99053.1 ANI99053.1 ANJ00685.1 ANJ00685.1 rnhB rnhB ANI99186.1 ANI99186.1 ANI99193.1 ANI99193.1 ANI99197.1 ANI99197.1 ANI99198.1 ANI99198.1 ANI99202.1 ANI99202.1 ANI99206.1 ANI99206.1 ANI99214.1 ANI99214.1 ANI99238.1 ANI99238.1 rhlE rhlE ANI99257.1 ANI99257.1 ANI99258.1 ANI99258.1 ANI99278.1 ANI99278.1 ANI99280.1 ANI99280.1 ANI99285.1 ANI99285.1 ANI99295.1 ANI99295.1 ANI99305.1 ANI99305.1 surE surE ANI99330.1 ANI99330.1 ANI99357.1 ANI99357.1 ANI99361.1 ANI99361.1 bpt bpt ANI99372.1 ANI99372.1 ANI99375.1 ANI99375.1 ANI99409.1 ANI99409.1 ANI99414.1 ANI99414.1 ANI99416.1 ANI99416.1 ANI99420.1 ANI99420.1 ANI99437.1 ANI99437.1 pnp pnp rnhA rnhA gloB gloB ANI99520.1 ANI99520.1 ANI99546.1 ANI99546.1 ANI99589.1 ANI99589.1 ANJ00747.1 ANJ00747.1 ANI99606.1 ANI99606.1 ANI99637.1 ANI99637.1 rph rph ANI99639.1 ANI99639.1 ANI99672.1 ANI99672.1 A8O14_06035 A8O14_06035 ANI99711.1 ANI99711.1 ANI99719.1 ANI99719.1 ANI99721.1 ANI99721.1 ANI99724.1 ANI99724.1 ANI99733.1 ANI99733.1 ANI99736.1 ANI99736.1 ANI99752.1 ANI99752.1 ANI99753.1 ANI99753.1 ANI99762.1 ANI99762.1 ANI99809.1 ANI99809.1 ANI99812.1 ANI99812.1 ANI99825.1 ANI99825.1 ANI99859.1 ANI99859.1 ANI99865.1 ANI99865.1 ANI99911.1 ANI99911.1 ANI99944.1 ANI99944.1 ANI99958.1 ANI99958.1 ANJ00002.1 ANJ00002.1 ANJ00027.1 ANJ00027.1 ANJ00032.1 ANJ00032.1 ANJ00050.1 ANJ00050.1 ANJ00075.1 ANJ00075.1 ANJ00077.1 ANJ00077.1 ANJ00123.1 ANJ00123.1 ANJ00136.1 ANJ00136.1 ANJ00142.1 ANJ00142.1 ureA ureA ureB ureB ureC ureC ANJ00174.1 ANJ00174.1 ANJ00176.1 ANJ00176.1 ANJ00178.1 ANJ00178.1 ANJ00202.1 ANJ00202.1 ANJ00801.1 ANJ00801.1 ANJ00209.1 ANJ00209.1 ANJ00214.1 ANJ00214.1 ANJ00221.1 ANJ00221.1 ANJ00222.1 ANJ00222.1 ANJ00223.1 ANJ00223.1 ANJ00224.1 ANJ00224.1 ANJ00251.1 ANJ00251.1 ANJ00279.1 ANJ00279.1 xseB xseB ANJ00292.1 ANJ00292.1 ANJ00320.1 ANJ00320.1 dut dut ANJ00341.1 ANJ00341.1 ANJ00436.1 ANJ00436.1 ANJ00438.1 ANJ00438.1 anmK anmK ANJ00547.1 ANJ00547.1 ANJ00562.1 ANJ00562.1 ANJ00850.1 ANJ00850.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (130 aa)
ANI98730.1Histidine triad nucleotide-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
ANI98790.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
ANI98791.1Aldehyde oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (707 aa)
rppHRNA pyrophosphohydrolase; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. (199 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (404 aa)
ANI98894.1Toxin of toxin-antitoxin system; Derived by automated computational analysis using gene prediction method: Protein Homology. (88 aa)
ANI98920.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (301 aa)
ANI98953.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
ANI98954.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (735 aa)
rneRibonuclease G; Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs. Belongs to the RNase E/G family. RNase E subfamily. (877 aa)
ANI99023.1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
ANI99052.1Flagellar biosynthesis protein FlgA; Derived by automated computational analysis using gene prediction method: Protein Homology. (94 aa)
ANI99053.1D-galactarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
ANJ00685.1ferredoxin--NADP(+) reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
rnhBRibonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (197 aa)
ANI99186.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
ANI99193.1Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
ANI99197.1Molybdopterin dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
ANI99198.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (169 aa)
ANI99202.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (389 aa)
ANI99206.1Alkene reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
ANI99214.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (309 aa)
ANI99238.13-hydroxyisobutyrate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HIBADH-related family. (292 aa)
rhlEATP-dependent RNA helicase RhlE; DEAD-box RNA helicase involved in ribosome assembly. Has RNA- dependent ATPase activity and unwinds double-stranded RNA. (429 aa)
ANI99257.1Fumarylacetoacetate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
ANI99258.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
ANI99278.1Galactarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
ANI99280.15-dehydro-4-deoxyglucarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (303 aa)
ANI99285.1Glucarate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (444 aa)
ANI99295.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (163 aa)
ANI99305.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
surE5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (263 aa)
ANI99330.1Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (227 aa)
ANI99357.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
ANI99361.14-oxalomesaconate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
bptArginyltransferase; Functions in the N-end rule pathway of protein degradation where it conjugates Leu from its aminoacyl-tRNA to the N-termini of proteins containing an N-terminal aspartate or glutamate. Belongs to the R-transferase family. Bpt subfamily. (248 aa)
ANI99372.1Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology. (209 aa)
ANI99375.13-hydroxybutyryl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
ANI99409.1Thiosulfohydrolase SoxB; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (577 aa)
ANI99414.1Thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (139 aa)
ANI99416.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (392 aa)
ANI99420.1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (128 aa)
ANI99437.1Dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (403 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (719 aa)
rnhAEfflux transporter periplasmic adaptor subunit; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (154 aa)
gloBHydroxyacylglutathione hydrolase; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid. (263 aa)
ANI99520.1Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
ANI99546.12-hydroxy-3-oxopropionate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
ANI99589.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
ANJ00747.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
ANI99606.15'-methylthioadenosine nucleosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (188 aa)
ANI99637.1YicC family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (246 aa)
ANI99639.1Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (196 aa)
ANI99672.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
A8O14_06035Transposase; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
ANI99711.1Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
ANI99719.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (118 aa)
ANI99721.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (569 aa)
ANI99724.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (563 aa)
ANI99733.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
ANI99736.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5'-nucleotidase family. (611 aa)
ANI99752.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (738 aa)
ANI99753.1(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (149 aa)
ANI99762.1Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)
ANI99809.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (311 aa)
ANI99812.1Galactonate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (515 aa)
ANI99825.1SlyX protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (66 aa)
ANI99859.1Alanine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the AlaDH/PNT family. (372 aa)
ANI99865.1RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (504 aa)
ANI99911.1ATP-dependent RNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DEAD box helicase family. (480 aa)
ANI99944.1Carboxylesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
ANI99958.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
ANJ00002.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
ANJ00027.13-hydroxyacyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
ANJ00032.1Racemase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the mandelate racemase/muconate lactonizing enzyme family. (377 aa)
ANJ00050.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
ANJ00075.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (292 aa)
ANJ00077.1Chlorophyll synthesis pathway protein BchC; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
ANJ00123.1Nitrite reductase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. (816 aa)
ANJ00136.1Addiction module toxin RelE; Derived by automated computational analysis using gene prediction method: Protein Homology. (92 aa)
ANJ00142.1acyl-CoA dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
ureAUrease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. (100 aa)
ureBUrease subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease beta subunit family. (112 aa)
ureCUrease subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)
ANJ00174.1NAD(P)H-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
ANJ00176.1hydroxymethylglutaryl-CoA lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
ANJ00178.12-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (326 aa)
ANJ00202.1Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0173 family. (285 aa)
ANJ00801.1DoxX family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
ANJ00209.1D-amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
ANJ00214.13-oxoadipate enol-lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
ANJ00221.1Benzoate 1,2-dioxygenase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
ANJ00222.1Benzoate 1,2-dioxygenase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
ANJ00223.1Catechol 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (306 aa)
ANJ00224.1Muconolactone delta-isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the muconolactone Delta-isomerase family. (96 aa)
ANJ00251.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (316 aa)
ANJ00279.1Reductase DrgA; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (77 aa)
ANJ00292.1Carboxymethylenebutenolidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
ANJ00320.1Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (403 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (149 aa)
ANJ00341.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (226 aa)
ANJ00436.1Sulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
ANJ00438.1Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (523 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (375 aa)
ANJ00547.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (364 aa)
ANJ00562.1Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
ANJ00850.1Sulfurase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
Your Current Organism:
Polynucleobacter wuianus
NCBI taxonomy Id: 1743168
Other names: CIP 111100, DSM 24008, P. wuianus, Polynucleobacter sp. QLW-P1FAT50C-4, Polynucleobacter wuianus Hahn et al. 2017, strain QLW-P1FAT50C-4
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