STRINGSTRING
pnp pnp rph rph Tel_00250 Tel_00250 rpoZ rpoZ Tel_00325 Tel_00325 coaD coaD Tel_00810 Tel_00810 Tel_00965 Tel_00965 Tel_01090 Tel_01090 Tel_01170 Tel_01170 Tel_02145 Tel_02145 nadD nadD Tel_02385 Tel_02385 Tel_02435 Tel_02435 dnaG dnaG tsaC tsaC glnE glnE hldE hldE Tel_02925 Tel_02925 rpoB rpoB rpoC rpoC rpoA rpoA Tel_04355 Tel_04355 pcnB pcnB glgC glgC Tel_05320 Tel_05320 Tel_05530 Tel_05530 Tel_05535 Tel_05535 fliA fliA Tel_06520 Tel_06520 Tel_06805 Tel_06805 Tel_06860 Tel_06860 dnaE2 dnaE2 glgC-2 glgC-2 glnD glnD Tel_08050 Tel_08050 Tel_08120 Tel_08120 ispD ispD Tel_08210 Tel_08210 Tel_08235 Tel_08235 Tel_08330 Tel_08330 dnaX dnaX cpsB cpsB Tel_08665 Tel_08665 Tel_09430 Tel_09430 kdsB kdsB Tel_09755 Tel_09755 Tel_09825 Tel_09825 Tel_10345 Tel_10345 Tel_10480 Tel_10480 Tel_12010 Tel_12010 mobA mobA Tel_12540 Tel_12540 Tel_12675 Tel_12675 Tel_12770 Tel_12770 Tel_12775 Tel_12775 dnaQ dnaQ Tel_13140 Tel_13140 Tel_14395 Tel_14395 glmU glmU polA polA selO selO Tel_15370 Tel_15370 Tel_15505 Tel_15505 Tel_15510 Tel_15510 Tel_15940 Tel_15940 sat sat Tel_16035 Tel_16035 Tel_16125 Tel_16125 cca cca
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (695 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (237 aa)
Tel_00250Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (95 aa)
Tel_00325RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (513 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
Tel_00810Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (309 aa)
Tel_00965Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
Tel_01090Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (587 aa)
Tel_01170Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
Tel_02145DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
nadDNicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (213 aa)
Tel_02385Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (281 aa)
Tel_02435tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (347 aa)
dnaGHypothetical protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (595 aa)
tsaCHypothetical protein; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Catalyzes the conversion of L-threonine, HCO(3)(-)/CO(2) and ATP to give threonylcarbamoyl-AMP (TC-AMP) as the acyladenylate intermediate, with the release of diphosphate. (184 aa)
glnEGlutamine-synthetase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transducti [...] (969 aa)
hldEBifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. In the N-terminal section; belongs to the carbohydrate kinase PfkB family. (474 aa)
Tel_02925Glucose-1-phosphate thymidylyltransferase; Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis. Belongs to the glucose-1-phosphate thymidylyltransferase family. (296 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1359 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1398 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (332 aa)
Tel_04355Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (146 aa)
pcnBpoly(A) polymerase; Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control. Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (404 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (421 aa)
Tel_05320Diguanylate cyclase response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (316 aa)
Tel_05530Acylneuraminate cytidylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
Tel_05535Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
fliAHypothetical protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (249 aa)
Tel_06520Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
Tel_06805Adenosylcobinamide kinase/adenosylcobinamide phosphate guanyltransferase; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (176 aa)
Tel_06860Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (497 aa)
dnaE2Hypothetical protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1083 aa)
glgC-2Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (405 aa)
glnDBifunctional uridylyltransferase/uridylyl-removing protein; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. (883 aa)
Tel_08050Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (276 aa)
Tel_08120DNA polymerase III subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (1155 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (235 aa)
Tel_08210Diguanylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
Tel_08235Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (312 aa)
Tel_08330UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (276 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (534 aa)
cpsBMannose-1-phosphate guanyltransferase; Capsular polysaccharide colanic acid biosynthesis protein; catalyzes the formation of GDP-mannose from GTP and alpha-D-mannose 1-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
Tel_08665UTP--glucose-1-phosphate uridylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
Tel_09430Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (259 aa)
Tel_09755threonylcarbamoyl-AMP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the SUA5 family. (206 aa)
Tel_09825Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
Tel_10345Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (81 aa)
Tel_10480Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (344 aa)
Tel_12010Molybdenum cofactor biosynthesis protein; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (176 aa)
mobAHypothetical protein; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (195 aa)
Tel_12540DNA polymerase III; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
Tel_12675Glucose-1-phosphate adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (407 aa)
Tel_12770ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
Tel_12775ATP-dependent DNA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (239 aa)
Tel_13140Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
Tel_14395DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (366 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (455 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (902 aa)
selOHypothetical protein; Catalyzes the transfer of adenosine 5'-monophosphate (AMP) to Ser, Thr or Tyr residues of target proteins (AMPylation). Belongs to the SELO family. (491 aa)
Tel_15370Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (83 aa)
Tel_15505Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
Tel_15510Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
Tel_15940Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
satATP sulfurylase; ATPS; converts ATP and sulfate to 5'phosphosulfate and pyrophosphate; in some organisms this enzyme is involved in the incorporation of inorganic sulfate while in others it is involved in the production of ATP in the reverse direction; the enzyme from Thermus thermophilus is dimeric and binds a zinc ion that is coordinated by cysteine and histidine residues that are not found in all related proteins but is found in some thermophilic organisms; Derived by automated computational analysis using gene prediction method: Protein Homology. (405 aa)
Tel_16035Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (541 aa)
Tel_16125Mannose-1-phosphate guanylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
cca2', 3'-cyclic nucleotide 2'-phosphodiesterase; Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'-nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases. (406 aa)
Your Current Organism:
Tenderia electrophaga
NCBI taxonomy Id: 1748243
Other names: C. Tenderia electrophaga, Candidatus Tenderia electrophaga, Gammaproteobacteria bacterium NRL1
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