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hisH hisH tadA tadA Tel_12835 Tel_12835 Tel_12910 Tel_12910 Tel_13045 Tel_13045 pyrC pyrC Tel_13520 Tel_13520 Tel_13565 Tel_13565 Tel_13685 Tel_13685 Tel_14480 Tel_14480 def-3 def-3 Tel_15610 Tel_15610 Tel_15895 Tel_15895 Tel_16025 Tel_16025 Tel_00900 Tel_00900 Tel_01185 Tel_01185 folE2 folE2 Tel_01360 Tel_01360 Tel_01590 Tel_01590 purH purH lpxC lpxC Tel_04250 Tel_04250 Tel_04255 Tel_04255 Tel_04550 Tel_04550 dcd dcd folD folD cheB cheB Tel_05470 Tel_05470 hisH-2 hisH-2 Tel_05550 Tel_05550 cheD cheD cheB-2 cheB-2 cheB-3 cheB-3 Tel_05935 Tel_05935 Tel_05940 Tel_05940 Tel_06645 Tel_06645 def def nadE nadE Tel_07020 Tel_07020 dapE dapE Tel_07240 Tel_07240 Tel_07255 Tel_07255 Tel_07880 Tel_07880 pyrG pyrG Tel_08220 Tel_08220 Tel_08225 Tel_08225 mtaD mtaD def-2 def-2 hisI hisI Tel_09925 Tel_09925 Tel_10225 Tel_10225
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
tadAHypothetical protein; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (154 aa)
Tel_12835Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
Tel_12910Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (162 aa)
Tel_13045Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (705 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (351 aa)
Tel_13520Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
Tel_13565Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
Tel_13685Polysaccharide deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
Tel_14480Acetylornithine deacetylase; Catalyzes the formation of L-ornithine from N(2)-acetyl-L-ornithine in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (386 aa)
def-3Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (167 aa)
Tel_15610Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the arginase family. (285 aa)
Tel_15895Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (221 aa)
Tel_16025Histone deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
Tel_00900N-acetyl-anhydromuranmyl-L-alanine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
Tel_01185Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (362 aa)
folE2GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. (264 aa)
Tel_01360Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. (425 aa)
Tel_01590Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (438 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (525 aa)
lpxCUDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. (303 aa)
Tel_04250Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
Tel_04255Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (348 aa)
Tel_04550Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (188 aa)
folDHypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (288 aa)
cheBChemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (346 aa)
Tel_05470Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
hisH-2Hypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (211 aa)
Tel_05550GlcNAc-PI de-N-acetylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
cheDChemotaxis protein CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family. (216 aa)
cheB-2Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (356 aa)
cheB-3Chemotaxis response regulator protein-glutamate methylesterase; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family. (348 aa)
Tel_05935N-carbamoylsarcosine amidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
Tel_05940Zn-dependent hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
Tel_06645Laccase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the multicopper oxidase YfiH/RL5 family. (251 aa)
defPeptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (166 aa)
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (538 aa)
Tel_07020Flagellar biosynthesis protein FlgJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (225 aa)
dapESuccinyl-diaminopimelate desuccinylase; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (380 aa)
Tel_07240Peptidase C26; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
Tel_07255Succinylglutamate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
Tel_07880Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (129 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (537 aa)
Tel_08220Acyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
Tel_08225Agmatine deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the agmatine deiminase family. (344 aa)
mtaDN-ethylammeline chlorohydrolase; Catalyzes the deamination of 5-methylthioadenosine and S- adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine. Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family. (442 aa)
def-2Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. (174 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (128 aa)
Tel_09925Cell wall hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (204 aa)
Tel_10225Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
Your Current Organism:
Tenderia electrophaga
NCBI taxonomy Id: 1748243
Other names: C. Tenderia electrophaga, Candidatus Tenderia electrophaga, Gammaproteobacteria bacterium NRL1
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