(18 nodes) Glutathione metabolism network (Tenderia electrophaga)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Tel_00490	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (872 aa)
	Tel_00530	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
	gshB	Glutathione synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family. (316 aa)
	Tel_01440	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
	Tel_02270	Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology. (449 aa)
	zwf	Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (469 aa)
	pepA	Aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides. (497 aa)
	Tel_04455	6-phosphogluconate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
	zwf-2	Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (504 aa)
	Tel_05210	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
	Tel_05985	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family. (185 aa)
	pepN	Derived by automated computational analysis using gene prediction method: Protein Homology. (884 aa)
	Tel_08800	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (694 aa)
	Tel_09625	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
	Tel_10120	Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology. (418 aa)
	zwf-3	Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (470 aa)
	Tel_14445	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
	speE	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (285 aa)

Your Current Organism:

Tenderia electrophaga

NCBI taxonomy Id: 1748243
Other names: C. Tenderia electrophaga, Candidatus Tenderia electrophaga, Gammaproteobacteria bacterium NRL1

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Tel_00490	Tel_05210	Tel_00490	Tel_05210	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
Tel_00490	Tel_09625	Tel_00490	Tel_09625	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.928
Tel_00490	speE	Tel_00490	Tel_15485	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Spermidine synthase; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.	0.902
Tel_00530	Tel_01440	Tel_00530	Tel_01440	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
Tel_00530	Tel_02270	Tel_00530	Tel_02270	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
Tel_00530	Tel_05985	Tel_00530	Tel_05985	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.	0.927
Tel_00530	Tel_08800	Tel_00530	Tel_08800	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.933
Tel_00530	Tel_14445	Tel_00530	Tel_14445	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
Tel_00530	gshB	Tel_00530	Tel_01435	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.	0.959
Tel_00530	pepA	Tel_00530	Tel_04360	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.	0.921
Tel_00530	pepN	Tel_00530	Tel_07820	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Derived by automated computational analysis using gene prediction method: Protein Homology.	0.933
Tel_01440	Tel_00530	Tel_01440	Tel_00530	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
Tel_01440	Tel_08800	Tel_01440	Tel_08800	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
Tel_01440	Tel_14445	Tel_01440	Tel_14445	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.900
Tel_01440	gshB	Tel_01440	Tel_01435	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the prokaryotic GSH synthase family.	0.993
Tel_01440	pepA	Tel_01440	Tel_04360	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.	0.903
Tel_01440	pepN	Tel_01440	Tel_07820	Glutamate--cysteine ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Derived by automated computational analysis using gene prediction method: Protein Homology.	0.907
Tel_02270	Tel_00530	Tel_02270	Tel_00530	Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.	Gamma-glutamyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.922
Tel_02270	Tel_05985	Tel_02270	Tel_05985	Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.	Glutathione peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutathione peroxidase family.	0.970
Tel_02270	Tel_10120	Tel_02270	Tel_10120	Catalyzes the reduction of 2 glutathione to glutathione disulfide; maintains high levels of reduced glutathione in the cytosol; involved in redox regulation and oxidative defense; Derived by automated computational analysis using gene prediction method: Protein Homology.	Converts isocitrate to alpha ketoglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419