STRINGSTRING
lpdA lpdA CEW89_06920 CEW89_06920 murI murI glcB glcB ilvC ilvC CEW89_07755 CEW89_07755 CEW89_11615 CEW89_11615 CEW89_05250 CEW89_05250 GCA_001550095_00697 GCA_001550095_00697 CEW89_00160 CEW89_00160 ldh ldh CEW89_19790 CEW89_19790 CEW89_19655 CEW89_19655 CEW89_05930 CEW89_05930 CEW89_05925 CEW89_05925 gabD gabD lpdA-2 lpdA-2 lldD lldD CEW89_01315 CEW89_01315 CEW89_01310 CEW89_01310 CEW89_08800 CEW89_08800 CEW89_01570 CEW89_01570 leuC leuC leuD leuD leuB leuB ilvD ilvD CEW89_14145 CEW89_14145 fadH fadH pckA pckA fumC fumC CEW89_03140 CEW89_03140 leuA leuA CEW89_18440 CEW89_18440 CEW89_18855 CEW89_18855 CEW89_06645 CEW89_06645 acnA acnA CEW89_04375 CEW89_04375 gabT gabT gabD-2 gabD-2 CEW89_03545 CEW89_03545 pdhA pdhA CEW89_06310 CEW89_06310 CEW89_06315 CEW89_06315 lpdA-3 lpdA-3 CEW89_10150 CEW89_10150 CEW89_10145 CEW89_10145 sucD sucD sucC sucC mdh mdh sdhC sdhC sdhD sdhD CEW89_10070 CEW89_10070 CEW89_10065 CEW89_10065 CEW89_00990 CEW89_00990 CEW89_00895 CEW89_00895 nifJ nifJ GCA_001550095_03626 GCA_001550095_03626 pyk pyk ilvE ilvE CEW89_12515 CEW89_12515 CEW89_12520 CEW89_12520 CEW89_12850 CEW89_12850
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lpdAUnannotated protein. (464 aa)
CEW89_06920Unannotated protein; Belongs to the citrate synthase family. (432 aa)
murIUnannotated protein; Provides the (R)-glutamate required for cell wall biosynthesis. (270 aa)
glcBUnannotated protein; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily. (713 aa)
ilvCUnannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa)
CEW89_07755Unannotated protein. (848 aa)
CEW89_11615Unannotated protein; Belongs to the glutamate synthase family. (510 aa)
CEW89_05250Unannotated protein; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (404 aa)
GCA_001550095_00697Unannotated protein. (456 aa)
CEW89_00160Unannotated protein. (455 aa)
ldhUnannotated protein; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. (310 aa)
CEW89_19790Unannotated protein. (616 aa)
CEW89_19655Unannotated protein; Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions. (112 aa)
CEW89_05930Unannotated protein. (733 aa)
CEW89_05925Unannotated protein. (410 aa)
gabDUnannotated protein; Belongs to the aldehyde dehydrogenase family. (489 aa)
lpdA-2Unannotated protein. (466 aa)
lldDUnannotated protein. (387 aa)
CEW89_01315Unannotated protein. (582 aa)
CEW89_01310Unannotated protein. (188 aa)
CEW89_08800Unannotated protein. (467 aa)
CEW89_01570Unannotated protein; Belongs to the pyruvate kinase family. (501 aa)
leuCUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (475 aa)
leuDUnannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa)
leuBUnannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (367 aa)
ilvDUnannotated protein; Belongs to the IlvD/Edd family. (614 aa)
CEW89_14145Unannotated protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (805 aa)
fadHUnannotated protein. (672 aa)
pckAUnannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa)
fumCUnannotated protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily. (464 aa)
CEW89_03140Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (542 aa)
leuAUnannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (525 aa)
CEW89_18440Unannotated protein. (760 aa)
CEW89_18855Unannotated protein. (728 aa)
CEW89_06645Unannotated protein. (929 aa)
acnAUnannotated protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (915 aa)
CEW89_04375Unannotated protein. (347 aa)
gabTUnannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
gabD-2Unannotated protein; Belongs to the aldehyde dehydrogenase family. (484 aa)
CEW89_03545Unannotated protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (468 aa)
pdhAUnannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (341 aa)
CEW89_06310Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (455 aa)
CEW89_06315Unannotated protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (435 aa)
lpdA-3Unannotated protein. (464 aa)
CEW89_10150Unannotated protein; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). (501 aa)
CEW89_10145Unannotated protein. (986 aa)
sucDUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (295 aa)
sucCUnannotated protein; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (397 aa)
mdhUnannotated protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. (320 aa)
sdhCUnannotated protein. (129 aa)
sdhDUnannotated protein. (123 aa)
CEW89_10070Unannotated protein; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily. (602 aa)
CEW89_10065Unannotated protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family. (259 aa)
CEW89_00990Unannotated protein. (445 aa)
CEW89_00895Unannotated protein. (555 aa)
nifJUnannotated protein. (1211 aa)
GCA_001550095_03626Unannotated protein. (310 aa)
pykUnannotated protein; Belongs to the pyruvate kinase family. (482 aa)
ilvEUnannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (289 aa)
CEW89_12515Unannotated protein. (1511 aa)
CEW89_12520Unannotated protein. (477 aa)
CEW89_12850Unannotated protein. (754 aa)
Your Current Organism:
Celeribacter ethanolicus
NCBI taxonomy Id: 1758178
Other names: C. ethanolicus, CGMCC 1.15406, Celeribacter ethanolicus Jian et al. 2016, Celeribacter sp. NH195, JCM 31095, strain NH195
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