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| | folD-2 | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (305 aa) |
| | folB | Unannotated protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (120 aa) |
| | glyA-2 | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (422 aa) |
| | CEW89_15805 | Unannotated protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. (468 aa) |
| | folD-3 | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (295 aa) |
| | aroE | Unannotated protein; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (276 aa) |
| | argG | Unannotated protein; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (407 aa) |
| | ubiG | Unannotated protein; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family. (244 aa) |
| | argJ | Unannotated protein; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (415 aa) |
| | CEW89_12530 | Unannotated protein. (328 aa) |
| | CEW89_12520 | Unannotated protein. (477 aa) |
| | CEW89_12515 | Unannotated protein. (1511 aa) |
| | queG | Unannotated protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (346 aa) |
| | ilvE | Unannotated protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (289 aa) |
| | dxs | Unannotated protein; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (642 aa) |
| | aroC | Unannotated protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (366 aa) |
| | dapF | Unannotated protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (278 aa) |
| | CEW89_13495 | Unannotated protein. (177 aa) |
| | CEW89_13475 | Unannotated protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (213 aa) |
| | ubiE | Unannotated protein; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (249 aa) |
| | ubiB | Unannotated protein; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily. (511 aa) |
| | CEW89_10425 | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (77 aa) |
| | CEW89_10705 | Unannotated protein. (276 aa) |
| | CEW89_10785 | Unannotated protein. (332 aa) |
| | CEW89_10790 | Unannotated protein. (236 aa) |
| | accA | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (320 aa) |
| | lysA | Unannotated protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (421 aa) |
| | argH | Unannotated protein. (463 aa) |
| | ubiA | Unannotated protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. (321 aa) |
| | CEW89_11305 | Unannotated protein. (206 aa) |
| | CEW89_11425 | Unannotated protein. (145 aa) |
| | dmpG | Unannotated protein; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (339 aa) |
| | GCA_001550095_03646 | Unannotated protein. (1147 aa) |
| | GCA_001550095_03605 | Unannotated protein. (624 aa) |
| | GCA_001550095_03588 | Unannotated protein. (404 aa) |
| | GCA_001550095_03583 | Unannotated protein. (389 aa) |
| | CEW89_00680 | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (457 aa) |
| | CEW89_00715 | Unannotated protein. (262 aa) |
| | accC | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (448 aa) |
| | accB | Unannotated protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (162 aa) |
| | CEW89_00990 | Unannotated protein. (445 aa) |
| | CEW89_01010 | Unannotated protein. (416 aa) |
| | CEW89_01050 | Unannotated protein. (107 aa) |
| | CEW89_09735 | Unannotated protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (232 aa) |
| | CEW89_09740 | Unannotated protein. (365 aa) |
| | panC | Unannotated protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (282 aa) |
| | panB | Unannotated protein; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (273 aa) |
| | CEW89_09890 | Unannotated protein; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (182 aa) |
| | fabD | Unannotated protein. (309 aa) |
| | acpP | Unannotated protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (77 aa) |
| | fabF | Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. (420 aa) |
| | cysE | Unannotated protein. (273 aa) |
| | purC | Unannotated protein; Belongs to the SAICAR synthetase family. (255 aa) |
| | CEW89_06050 | Unannotated protein. (348 aa) |
| | CEW89_05995 | Unannotated protein. (433 aa) |
| | argF | Unannotated protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (309 aa) |
| | argD | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (388 aa) |
| | CEW89_18175 | Unannotated protein. (233 aa) |
| | carB | Unannotated protein; Belongs to the CarB family. (1129 aa) |
| | proC | Unannotated protein; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (268 aa) |
| | CEW89_18110 | Unannotated protein. (82 aa) |
| | hisD | Unannotated protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa) |
| | CEW89_17775 | Unannotated protein; Belongs to the aspartokinase family. (411 aa) |
| | pabB | Unannotated protein. (372 aa) |
| | mtnP | Unannotated protein; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily. (293 aa) |
| | apt | Unannotated protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (176 aa) |
| | CEW89_17695 | Unannotated protein. (460 aa) |
| | CEW89_15555 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (347 aa) |
| | CEW89_15610 | Unannotated protein. (466 aa) |
| | CEW89_15650 | Unannotated protein. (113 aa) |
| | GCA_001550095_02991 | Unannotated protein. (189 aa) |
| | CEW89_03415 | Unannotated protein. (678 aa) |
| | CEW89_03425 | Unannotated protein. (329 aa) |
| | CEW89_03565 | Unannotated protein; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (461 aa) |
| | CEW89_03645 | Unannotated protein. (456 aa) |
| | CEW89_03730 | Unannotated protein. (95 aa) |
| | hisI | Unannotated protein; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (130 aa) |
| | fabZ | Unannotated protein; Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs. (159 aa) |
| | CEW89_03875 | Unannotated protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (242 aa) |
| | aroB | Unannotated protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (369 aa) |
| | aroK | Unannotated protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (181 aa) |
| | CEW89_03995 | Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (403 aa) |
| | CEW89_04000 | Unannotated protein. (88 aa) |
| | CEW89_04745 | Unannotated protein. (237 aa) |
| | CEW89_04660 | Unannotated protein. (330 aa) |
| | CEW89_04640 | Unannotated protein. (314 aa) |
| | CEW89_04415 | Unannotated protein. (243 aa) |
| | CEW89_04380 | Unannotated protein. (145 aa) |
| | CEW89_04360 | Unannotated protein. (248 aa) |
| | CEW89_04350 | Unannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). (202 aa) |
| | thiG | Unannotated protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (253 aa) |
| | thiS | Unannotated protein. (65 aa) |
| | thiC | Unannotated protein; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (595 aa) |
| | nadA | Unannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (322 aa) |
| | serS | Unannotated protein; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (430 aa) |
| | CEW89_06685 | Unannotated protein. (425 aa) |
| | GCA_001550095_02602 | Unannotated protein. (667 aa) |
| | GCA_001550095_02556 | Unannotated protein. (382 aa) |
| | GCA_001550095_02555 | Unannotated protein. (157 aa) |
| | GCA_001550095_02550 | Unannotated protein. (342 aa) |
| | GCA_001550095_02547 | Unannotated protein. (304 aa) |
| | pobA | Unannotated protein. (391 aa) |
| | CEW89_18610 | Unannotated protein. (367 aa) |
| | glyA | Unannotated protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (431 aa) |
| | CEW89_15890 | Unannotated protein. (342 aa) |
| | CEW89_15990 | Unannotated protein. (317 aa) |
| | bluB | Unannotated protein. (215 aa) |
| | CEW89_16330 | Unannotated protein. (343 aa) |
| | CEW89_16530 | Unannotated protein. (310 aa) |
| | leuA | Unannotated protein; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. (525 aa) |
| | GCA_001550095_02232 | Unannotated protein. (1469 aa) |
| | CEW89_03140 | Unannotated protein; Belongs to the alpha-IPM synthase/homocitrate synthase family. (542 aa) |
| | cobB | Unannotated protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (422 aa) |
| | cbiD | Unannotated protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (320 aa) |
| | CEW89_03320 | Unannotated protein. (245 aa) |
| | CEW89_03345 | Unannotated protein. (316 aa) |
| | pgi | Unannotated protein; Belongs to the GPI family. (540 aa) |
| | CEW89_14910 | Unannotated protein. (275 aa) |
| | pckA | Unannotated protein; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. (532 aa) |
| | acpS | Unannotated protein; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (134 aa) |
| | pdxJ | Unannotated protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (248 aa) |
| | folK | Unannotated protein. (202 aa) |
| | cobM | Unannotated protein. (255 aa) |
| | cobJ | Unannotated protein. (606 aa) |
| | cobI | Unannotated protein; Belongs to the precorrin methyltransferase family. (238 aa) |
| | CEW89_14700 | Unannotated protein. (398 aa) |
| | CEW89_14695 | Unannotated protein. (212 aa) |
| | CEW89_14665 | Unannotated protein. (319 aa) |
| | cobD | Unannotated protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (300 aa) |
| | CEW89_14640 | Unannotated protein. (224 aa) |
| | cobW | Unannotated protein. (355 aa) |
| | cobO | Unannotated protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (204 aa) |
| | dapA | Unannotated protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (290 aa) |
| | CEW89_14475 | Unannotated protein. (100 aa) |
| | accD | Unannotated protein; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (321 aa) |
| | CEW89_14380 | Unannotated protein; Belongs to the folylpolyglutamate synthase family. (424 aa) |
| | asd | Unannotated protein; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (340 aa) |
| | ilvD | Unannotated protein; Belongs to the IlvD/Edd family. (614 aa) |
| | leuB | Unannotated protein; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (367 aa) |
| | leuD | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (201 aa) |
| | leuC | Unannotated protein; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (475 aa) |
| | dapE | Unannotated protein; Catalyzes the hydrolysis of N-succinyl-L,L-diaminopimelic acid (SDAP), forming succinate and LL-2,6-diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls; Belongs to the peptidase M20A family. DapE subfamily. (381 aa) |
| | CEW89_13595 | Unannotated protein. (401 aa) |
| | dapD | Unannotated protein; Belongs to the transferase hexapeptide repeat family. (275 aa) |
| | serB | Unannotated protein. (292 aa) |
| | CEW89_13535 | Unannotated protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (380 aa) |
| | CEW89_13530 | Unannotated protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (530 aa) |
| | CEW89_14925 | Unannotated protein; Belongs to the Cob(I)alamin adenosyltransferase family. (192 aa) |
| | kdsA | Unannotated protein; Belongs to the KdsA family. (275 aa) |
| | pdxA | Unannotated protein; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (334 aa) |
| | plsX | Unannotated protein; Catalyzes the reversible formation of acyl-phosphate (acyl- PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA. (382 aa) |
| | fabH | Unannotated protein; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched-chain and/or straight-chain of fatty acids; Belongs to the thiolase-like superfamily. FabH family. (324 aa) |
| | CEW89_01710 | Unannotated protein. (208 aa) |
| | proA | Unannotated protein; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa) |
| | proB | Unannotated protein; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (370 aa) |
| | tgt | Unannotated protein; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. [...] (381 aa) |
| | tpiA | Unannotated protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa) |
| | argB | Unannotated protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (296 aa) |
| | metF | Unannotated protein; Belongs to the methylenetetrahydrofolate reductase family. (277 aa) |
| | CEW89_08270 | Unannotated protein. (367 aa) |
| | cobQ | Unannotated protein; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (483 aa) |
| | CEW89_08790 | Unannotated protein; Belongs to the UbiA prenyltransferase family. (478 aa) |
| | CEW89_01175 | Unannotated protein. (555 aa) |
| | trpE | Unannotated protein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (504 aa) |
| | gpt | Unannotated protein; Acts on guanine, xanthine and to a lesser extent hypoxanthine; Belongs to the purine/pyrimidine phosphoribosyltransferase family. XGPT subfamily. (167 aa) |
| | CEW89_01230 | Unannotated protein. (267 aa) |
| | pdxH | Unannotated protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (205 aa) |
| | CEW89_01310 | Unannotated protein. (188 aa) |
| | CEW89_16750 | Unannotated protein. (262 aa) |
| | CEW89_16760 | Unannotated protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (409 aa) |
| | CEW89_16765 | Unannotated protein; Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to E- (2)-decenoyl-ACP and then its isomerization to Z-(3)-decenoyl-ACP. Can catalyze the dehydratase reaction for beta-hydroxyacyl-ACPs with saturated chain lengths up to 16:0, being most active on intermediate chain length. (169 aa) |
| | queF | Unannotated protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). Belongs to the GTP cyclohydrolase I family. QueF type 1 subfamily. (154 aa) |
| | aroA | Unannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (449 aa) |
| | trpF | Unannotated protein; Belongs to the TrpF family. (213 aa) |
| | trpB | Unannotated protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (416 aa) |
| | trpA | Unannotated protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (263 aa) |
| | CEW89_17010 | Unannotated protein. (388 aa) |
| | CEW89_17255 | Unannotated protein. (228 aa) |
| | CEW89_17260 | Unannotated protein; Belongs to the glutamate synthase family. (441 aa) |
| | aroQ | Unannotated protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (145 aa) |
| | CEW89_17525 | Unannotated protein. (105 aa) |
| | folD | Unannotated protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (300 aa) |
| | CEW89_05920 | Unannotated protein. (265 aa) |
| | CEW89_19180 | Unannotated protein. (510 aa) |
| | CEW89_19305 | Unannotated protein. (290 aa) |
| | CEW89_19400 | Unannotated protein. (199 aa) |
| | glpX | Unannotated protein. (324 aa) |
| | CEW89_19430 | Unannotated protein. (436 aa) |
| | ribD | Unannotated protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (366 aa) |
| | CEW89_19530 | Unannotated protein. (199 aa) |
| | ribB | Unannotated protein; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. (367 aa) |
| | ribH | Unannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (181 aa) |
| | cobS-2 | Unannotated protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (250 aa) |
| | cobT-2 | Unannotated protein; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (334 aa) |
| | hisE | Unannotated protein. (104 aa) |
| | hisF | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (265 aa) |
| | hisA | Unannotated protein. (240 aa) |
| | hisH | Unannotated protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (212 aa) |
| | hisB | Unannotated protein. (195 aa) |
| | GCA_001550095_00832 | Unannotated protein. (1147 aa) |
| | cobT | Unannotated protein. (624 aa) |
| | CEW89_00265 | Unannotated protein. (404 aa) |
| | carA | Unannotated protein; Belongs to the CarA family. (389 aa) |
| | gph | Unannotated protein. (211 aa) |
| | hisC | Unannotated protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (364 aa) |
| | CEW89_09310 | Unannotated protein. (315 aa) |
| | ribF | Unannotated protein; Belongs to the ribF family. (308 aa) |
| | CEW89_09135 | Unannotated protein. (372 aa) |
| | CEW89_04980 | Unannotated protein. (400 aa) |
| | CEW89_05100 | Unannotated protein. (148 aa) |
| | hpt | Unannotated protein; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (185 aa) |
| | lipA | Unannotated protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (316 aa) |
| | metAA | Unannotated protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family. (307 aa) |
| | CEW89_05450 | Unannotated protein; Oxidizes proline to glutamate for use as a carbon and nitrogen source; Belongs to the aldehyde dehydrogenase family. In the N-terminal section; belongs to the proline dehydrogenase family. (1135 aa) |
| | CEW89_05545 | Unannotated protein. (426 aa) |
| | CEW89_05570 | Unannotated protein. (348 aa) |
| | CEW89_12195 | Unannotated protein. (454 aa) |
| | CEW89_12170 | Unannotated protein. (286 aa) |
| | CEW89_12090 | Unannotated protein. (209 aa) |
| | CEW89_11980 | Unannotated protein. (267 aa) |
| | ribA | Unannotated protein; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (362 aa) |
| | CEW89_11870 | Unannotated protein. (411 aa) |
| | dapB | Unannotated protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (269 aa) |
| | CEW89_11615 | Unannotated protein; Belongs to the glutamate synthase family. (510 aa) |
| | GCA_001550095_00235 | Unannotated protein. (246 aa) |
| | folP | Unannotated protein. (342 aa) |
| | ilvC | Unannotated protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (340 aa) |
| | CEW89_07560 | Unannotated protein. (221 aa) |
| | alr | Unannotated protein; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (346 aa) |
| | CEW89_07150 | Unannotated protein. (170 aa) |
| | argC | Unannotated protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (342 aa) |
| | trpC | Unannotated protein; Belongs to the TrpC family. (266 aa) |
| | trpD | Unannotated protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (338 aa) |
| | queA | Unannotated protein; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (353 aa) |
