STRINGSTRING
SGUI_0062 SGUI_0062 dnaJ dnaJ SGUI_0075 SGUI_0075 recO recO SGUI_0102 SGUI_0102 dnaG dnaG SGUI_0105 SGUI_0105 SGUI_0122 SGUI_0122 SGUI_0137 SGUI_0137 SGUI_0158 SGUI_0158 SGUI_0165 SGUI_0165 SGUI_0172 SGUI_0172 SGUI_0177 SGUI_0177 priA priA polA polA uvrB uvrB uvrA uvrA uvrC uvrC dinB dinB SGUI_0323 SGUI_0323 SGUI_0348 SGUI_0348 SGUI_0363 SGUI_0363 SGUI_0414 SGUI_0414 xerD xerD ruvB ruvB ruvA ruvA ruvC ruvC SGUI_0514 SGUI_0514 SGUI_0516 SGUI_0516 SGUI_0534 SGUI_0534 SGUI_0535 SGUI_0535 SGUI_0595 SGUI_0595 SGUI_0613 SGUI_0613 SGUI_0668 SGUI_0668 SGUI_0678 SGUI_0678 SGUI_0705 SGUI_0705 SGUI_0742 SGUI_0742 SGUI_0790 SGUI_0790 dinB-2 dinB-2 SGUI_0800 SGUI_0800 SGUI_0803 SGUI_0803 SGUI_0819 SGUI_0819 SGUI_0865 SGUI_0865 SGUI_0907 SGUI_0907 SGUI_0908 SGUI_0908 SGUI_0947 SGUI_0947 SGUI_0960 SGUI_0960 lexA lexA SGUI_0974 SGUI_0974 SGUI_0981 SGUI_0981 SGUI_0994 SGUI_0994 SGUI_1014 SGUI_1014 SGUI_1035 SGUI_1035 SGUI_1073 SGUI_1073 SGUI_1075 SGUI_1075 SGUI_1116 SGUI_1116 SGUI_1151 SGUI_1151 ligA ligA nucS nucS SGUI_1279 SGUI_1279 SGUI_1327 SGUI_1327 mfd mfd SGUI_1354 SGUI_1354 radA radA disA disA SGUI_1442 SGUI_1442 ku ku SGUI_1449 SGUI_1449 SGUI_1450 SGUI_1450 SGUI_1451 SGUI_1451 SGUI_1454 SGUI_1454 SGUI_1455 SGUI_1455 SGUI_1477 SGUI_1477 topA topA SGUI_1491 SGUI_1491 nth nth recR recR dnaX dnaX SGUI_1533 SGUI_1533 SGUI_1549 SGUI_1549 SGUI_1552 SGUI_1552 SGUI_1554 SGUI_1554 SGUI_1602 SGUI_1602 SGUI_1603 SGUI_1603 SGUI_1604 SGUI_1604 SGUI_1605 SGUI_1605 SGUI_1672 SGUI_1672 SGUI_1713 SGUI_1713 SGUI_1762 SGUI_1762 SGUI_1778 SGUI_1778 SGUI_1807 SGUI_1807 SGUI_1810 SGUI_1810 gyrA gyrA gyrB gyrB recF recF SGUI_1871 SGUI_1871 dnaA dnaA SGUI_1911 SGUI_1911 SGUI_1927 SGUI_1927 SGUI_1932 SGUI_1932 SGUI_1933 SGUI_1933 SGUI_1937 SGUI_1937 SGUI_1942 SGUI_1942 SGUI_1943 SGUI_1943 SGUI_1944 SGUI_1944 SGUI_1945 SGUI_1945 SGUI_1949 SGUI_1949 SGUI_1950 SGUI_1950 SGUI_1951 SGUI_1951 SGUI_1952 SGUI_1952 SGUI_1970 SGUI_1970 SGUI_2073 SGUI_2073 SGUI_2104 SGUI_2104 SGUI_2122 SGUI_2122 SGUI_2124 SGUI_2124 SGUI_2150 SGUI_2150 SGUI_2210 SGUI_2210 SGUI_2211 SGUI_2211 SGUI_2233 SGUI_2233 SGUI_2302 SGUI_2302 SGUI_2340 SGUI_2340 SGUI_2341 SGUI_2341 SGUI_2342 SGUI_2342 recD recD recB recB recC recC SGUI_2561 SGUI_2561 SGUI_2592 SGUI_2592 SGUI_2596 SGUI_2596 SGUI_2645 SGUI_2645 SGUI_2647 SGUI_2647 SGUI_2651 SGUI_2651 SGUI_2653 SGUI_2653 SGUI_2655 SGUI_2655 SGUI_2656 SGUI_2656 SGUI_2657 SGUI_2657 SGUI_2719 SGUI_2719 SGUI_2720 SGUI_2720 ung ung SGUI_2872 SGUI_2872 SGUI_2875 SGUI_2875 SGUI_2876 SGUI_2876 SGUI_2877 SGUI_2877 SGUI_2878 SGUI_2878 xseB xseB xseA xseA SGUI_2954 SGUI_2954 SGUI_2988 SGUI_2988 SGUI_2998 SGUI_2998 SGUI_3015 SGUI_3015 SGUI_3020 SGUI_3020 SGUI_3021 SGUI_3021 SGUI_3141 SGUI_3141 recA recA SGUI_3185 SGUI_3185 SGUI_3191 SGUI_3191 SGUI_3201 SGUI_3201 SGUI_3230 SGUI_3230 SGUI_3232 SGUI_3232 mutM mutM smc smc SGUI_3266 SGUI_3266 xerC xerC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGUI_0062Hypothetical protein. (295 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (374 aa)
SGUI_0075Alkylated DNA repair protein AlkB. (239 aa)
recODNA recombination and repair protein RecO; Involved in DNA repair and RecF pathway recombination. (243 aa)
SGUI_0102ATP-dependent DNA ligase. (320 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (644 aa)
SGUI_0105Hypothetical protein. (189 aa)
SGUI_0122Hypothetical protein. (297 aa)
SGUI_0137Hypothetical protein. (118 aa)
SGUI_0158DNA-3-methyladenine glycosylase II; Belongs to the DNA glycosylase MPG family. (209 aa)
SGUI_0165DNA repair protein RecN. (629 aa)
SGUI_0172ADP-ribose pyrophosphatase. (201 aa)
SGUI_0177ATPase, AAA family. (466 aa)
priAHelicase PriA essential for oriC/DnaA-independent DNA replication; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (708 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (898 aa)
uvrBExcinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] (702 aa)
uvrAExcinuclease ABC subunit A; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. (988 aa)
uvrCExcinuclease ABC subunit C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. (639 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (479 aa)
SGUI_0323Hypothetical protein. (272 aa)
SGUI_0348DNA polymerase I. (322 aa)
SGUI_0363Single-strand binding protein/Primosomal replication protein n. (118 aa)
SGUI_0414Hypothetical protein. (467 aa)
xerDSite-specific recombinase XerD; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (325 aa)
ruvBHolliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. (385 aa)
ruvAHolliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. (202 aa)
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (223 aa)
SGUI_0514ATP-dependent DNA ligase LigC. (359 aa)
SGUI_0516ATP-dependent DNA ligase. (358 aa)
SGUI_0534Ribonucleotide reductase of class Ia (aerobic), alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (868 aa)
SGUI_0535Ribonucleotide reductase of class Ia (aerobic), beta subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (338 aa)
SGUI_0595Thymidine kinase. (254 aa)
SGUI_0613Topoisomerase IV subunit A. (826 aa)
SGUI_0668Hypothetical protein. (52 aa)
SGUI_0678ERCC4-type nuclease. (351 aa)
SGUI_0705ERCC4-type nuclease. (315 aa)
SGUI_0742Photolyase protein family. (489 aa)
SGUI_0790Topoisomerase IV subunit B. (702 aa)
dinB-2DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (388 aa)
SGUI_0800DNA polymerase III alpha subunit; Belongs to the DNA polymerase type-C family. DnaE2 subfamily. (1352 aa)
SGUI_0803Mobile element protein. (361 aa)
SGUI_0819DNA polymerase III epsilon subunit. (598 aa)
SGUI_0865DNA polymerase III alpha subunit. (1370 aa)
SGUI_0907Mobile element protein. (511 aa)
SGUI_0908Mobile element protein; Belongs to the DnaA family. (266 aa)
SGUI_0947Ribonucleotide reductase of class II (coenzyme B12-dependent); Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (962 aa)
SGUI_0960ATP-dependent DNA helicase RecQ. (734 aa)
lexASOS-response repressor and protease LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. (242 aa)
SGUI_0974Competence protein ComEA helix-hairpin-helix repeat protein. (310 aa)
SGUI_0981DNA polymerase III delta subunit. (325 aa)
SGUI_0994Hypothetical protein. (116 aa)
SGUI_1014Hypothetical protein. (405 aa)
SGUI_1035Hypothetical protein. (313 aa)
SGUI_1073Hypothetical protein. (331 aa)
SGUI_1075Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (278 aa)
SGUI_1116DNA polymerase-like protein. (347 aa)
SGUI_1151Single-strand binding protein. (178 aa)
ligADNA ligase; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (716 aa)
nucSHypothetical protein; Cleaves both 3' and 5' ssDNA extremities of branched DNA structures; Belongs to the NucS endonuclease family. (234 aa)
SGUI_1279Signal peptidase protein. (123 aa)
SGUI_1327Uracil-DNA glycosylase, family 5. (275 aa)
mfdTranscription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. (1215 aa)
SGUI_1354Putative deoxyribonuclease YcfH. (281 aa)
radADNA repair protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function. (413 aa)
disADNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP likely acts as a signaling molecule that may couple DNA integrity with a cellular process. (360 aa)
SGUI_1442A/G-specific adenine glycosylase. (304 aa)
kuKu domain protein; With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD. Belongs to the prokaryotic Ku family. (305 aa)
SGUI_1449ATP-dependent DNA ligase clustered with Ku protein, LigD. (307 aa)
SGUI_1450ATP-dependent DNA ligase clustered with Ku protein, LigD. (282 aa)
SGUI_1451Histone protein Lsr2. (110 aa)
SGUI_1454Methylated-DNA--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (168 aa)
SGUI_1455Methylated-DNA--protein-cysteine methyltransferase. (516 aa)
SGUI_1477DNA polymerase III delta prime subunit. (387 aa)
topADNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] (900 aa)
SGUI_1491Putative helicase. (737 aa)
nthEndonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. (247 aa)
recRRecombination protein RecR; May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO. (200 aa)
dnaXDNA polymerase III subunits gamma and tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (770 aa)
SGUI_1533Hypothetical protein. (343 aa)
SGUI_1549Endonuclease IV. (353 aa)
SGUI_1552Exodeoxyribonuclease III. (265 aa)
SGUI_1554Hypothetical protein. (193 aa)
SGUI_1602Excinuclease ABC subunit A. (810 aa)
SGUI_1603Mobile element protein. (266 aa)
SGUI_1604Mobile element protein. (511 aa)
SGUI_1605Mobile element protein. (213 aa)
SGUI_1672Mobile element protein. (397 aa)
SGUI_1713Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (286 aa)
SGUI_1762Formamidopyrimidine-DNA glycosylase. (283 aa)
SGUI_1778ATP-dependent DNA ligase LigC; Belongs to the ATP-dependent DNA ligase family. (560 aa)
SGUI_1807Exodeoxyribonuclease III. (306 aa)
SGUI_1810Excinuclease ABC subunit A. (785 aa)
gyrADNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (900 aa)
gyrBDNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (732 aa)
recFDNA recombination and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. (414 aa)
SGUI_1871DNA polymerase III beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (377 aa)
dnaAChromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. Belongs to the DnaA family. (501 aa)
SGUI_1911Single-stranded DNA-binding protein. (205 aa)
SGUI_1927Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily. (885 aa)
SGUI_1932Putative transposase. (728 aa)
SGUI_1933Putative ATP/GTP-binding protein. (349 aa)
SGUI_1937Hypothetical protein. (553 aa)
SGUI_1942Mobile element protein. (199 aa)
SGUI_1943Mobile element protein. (511 aa)
SGUI_1944Mobile element protein. (266 aa)
SGUI_1945Mobile element protein. (238 aa)
SGUI_1949Mobile element protein. (71 aa)
SGUI_1950Mobile element protein. (115 aa)
SGUI_1951Mobile element protein. (346 aa)
SGUI_1952Mobile element protein. (266 aa)
SGUI_1970Hypothetical protein. (53 aa)
SGUI_2073Putative cytoplasmic protein clustered with trehalase. (379 aa)
SGUI_2104Hypothetical protein. (467 aa)
SGUI_2122Mobile element protein. (267 aa)
SGUI_2124Hypothetical protein. (467 aa)
SGUI_2150Putative RecF protein. (407 aa)
SGUI_2210Mobile element protein. (107 aa)
SGUI_2211Mobile element protein. (258 aa)
SGUI_2233Insertion element IS1415 transposase. (189 aa)
SGUI_2302Putative integral membrane protein. (564 aa)
SGUI_2340Mobile element protein. (294 aa)
SGUI_2341Mobile element protein. (340 aa)
SGUI_2342Mobile element protein. (294 aa)
recDExodeoxyribonuclease V alpha chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...] (673 aa)
recBExodeoxyribonuclease V beta chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repai [...] (1139 aa)
recCExodeoxyribonuclease V gamma chain; A helicase/nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repa [...] (1169 aa)
SGUI_2561DNA-dependent DNA polymerase beta chain. (358 aa)
SGUI_2592Putative hydrolase mutT1. (316 aa)
SGUI_2596Hypothetical protein; May play a role in the intracellular transport of hydrophobic ligands. (164 aa)
SGUI_2645Phage integrase, site-specific tyrosine recombinase; Belongs to the 'phage' integrase family. (352 aa)
SGUI_2647Mobile element protein. (363 aa)
SGUI_2651Hypothetical protein. (270 aa)
SGUI_2653Phage-related integrase/recombinase. (371 aa)
SGUI_2655Mobile element protein. (221 aa)
SGUI_2656Mobile element protein. (79 aa)
SGUI_2657Mobile element protein. (258 aa)
SGUI_2719McrBC 5-methylcytosine restriction system component-like. (398 aa)
SGUI_2720Endonuclease. (667 aa)
ungUracil-DNA glycosylase, family 1; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine. (225 aa)
SGUI_2872Hypothetical protein. (659 aa)
SGUI_2875Type I restriction-modification system, DNA-methyltransferase subunit M. (541 aa)
SGUI_2876Type I restriction-modification system, specificity subunit S. (131 aa)
SGUI_2877Type I restriction-modification system, restriction subunit R; Subunit R is required for both nuclease and ATPase activities, but not for modification. (1064 aa)
SGUI_2878Hypothetical protein. (323 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (90 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (411 aa)
SGUI_2954DNA recombination protein RmuC. (427 aa)
SGUI_2988Putative mutT-like protein; Belongs to the Nudix hydrolase family. (134 aa)
SGUI_2998DNA-3-methyladenine glycosylase. (218 aa)
SGUI_3015Putative metal-dependent phosphoesterases (PHP family). (228 aa)
SGUI_3020ATP-dependent DNA helicase. (1066 aa)
SGUI_3021ATP-dependent DNA helicase; Belongs to the helicase family. UvrD subfamily. (1096 aa)
SGUI_3141Formamidopyrimidine-DNA glycosylase. (279 aa)
recARecA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. (364 aa)
SGUI_3185Peptidase, M23/M37 family. (567 aa)
SGUI_3191Mobile element protein. (124 aa)
SGUI_3201Site-specific recombinase XerD; Belongs to the 'phage' integrase family. (309 aa)
SGUI_3230Integrase. (110 aa)
SGUI_3232Transposon Tn21 resolvase. (202 aa)
mutMFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (297 aa)
smcChromosome partition protein smc; Required for chromosome condensation and partitioning. Belongs to the SMC family. (1223 aa)
SGUI_3266G:T/U mismatch-specific uracil/thymine DNA-glycosylase. (203 aa)
xerCTyrosine recombinase XerC; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (307 aa)
Your Current Organism:
Serinicoccus sp. JLT9
NCBI taxonomy Id: 1758689
Other names: S. sp. JLT9
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