STRINGSTRING
dnaJ dnaJ ybeY ybeY dnaG dnaG alaS alaS mshC mshC SGUI_0375 SGUI_0375 SGUI_0404 SGUI_0404 hisD hisD SGUI_0439 SGUI_0439 ribA ribA SGUI_0500 SGUI_0500 SGUI_0515 SGUI_0515 SGUI_0517 SGUI_0517 SGUI_0609 SGUI_0609 SGUI_0623 SGUI_0623 SGUI_0675 SGUI_0675 SGUI_0681 SGUI_0681 SGUI_0740 SGUI_0740 SGUI_0866 SGUI_0866 SGUI_0869 SGUI_0869 SGUI_0935 SGUI_0935 SGUI_0937 SGUI_0937 nrdR nrdR cobB cobB SGUI_0998 SGUI_0998 SGUI_1074 SGUI_1074 SGUI_1075 SGUI_1075 ileS ileS clpX clpX SGUI_1122 SGUI_1122 SGUI_1161 SGUI_1161 SGUI_1210 SGUI_1210 mca mca SGUI_1326 SGUI_1326 SGUI_1455 SGUI_1455 ftsH ftsH SGUI_1539 SGUI_1539 SGUI_1549 SGUI_1549 SGUI_1686 SGUI_1686 SGUI_1713 SGUI_1713 SGUI_1762 SGUI_1762 SGUI_1827 SGUI_1827 SGUI_2002 SGUI_2002 SGUI_2069 SGUI_2069 SGUI_2071 SGUI_2071 SGUI_2075 SGUI_2075 SGUI_2146 SGUI_2146 SGUI_2169 SGUI_2169 SGUI_2195 SGUI_2195 hutI hutI tadA tadA SGUI_2588 SGUI_2588 SGUI_2619 SGUI_2619 cysS cysS SGUI_2760 SGUI_2760 SGUI_2762 SGUI_2762 SGUI_2805 SGUI_2805 htpX htpX rpoC rpoC SGUI_2943 SGUI_2943 SGUI_2990 SGUI_2990 SGUI_3096 SGUI_3096 add add SGUI_3123 SGUI_3123 rnj rnj SGUI_3141 SGUI_3141 SGUI_3149 SGUI_3149 SGUI_3204 SGUI_3204 gltX gltX mutM mutM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (374 aa)
ybeYMetal-dependent hydrolase YbeY, involved in rRNA and/or ribosome maturation and assembly; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. (172 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (644 aa)
alaSAlanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. (896 aa)
mshCL-cysteine:1D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase MshC; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily. (425 aa)
SGUI_0375Homocysteine S-methyltransferase. (336 aa)
SGUI_0404Acetylornithine deacetylase. (399 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (435 aa)
SGUI_0439Aspartyl aminopeptidase. (446 aa)
ribA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family. (449 aa)
SGUI_0500Threonine dehydrogenase and related Zn-dependent dehydrogenase. (335 aa)
SGUI_0515Mannose-6-phosphate isomerase. (397 aa)
SGUI_0517Peptide methionine sulfoxide reductase MsrB. (151 aa)
SGUI_0609Aryldialkylphosphatase related protein. (419 aa)
SGUI_0623Alcohol dehydrogenase. (348 aa)
SGUI_0675Putative helicase. (1128 aa)
SGUI_0681Threonine dehydrogenase and related Zn-dependent dehydrogenase. (393 aa)
SGUI_0740Carboxypeptidase G2. (385 aa)
SGUI_0866Carboxypeptidase B. (1011 aa)
SGUI_0869Putative DNA-binding protein. (153 aa)
SGUI_0935Putative metallopeptidase. (476 aa)
SGUI_0937Alcohol dehydrogenase. (352 aa)
nrdRRibonucleotide reductase transcriptional regulator NrdR; Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes; Belongs to the NrdR family. (161 aa)
cobBNAD-dependent protein deacetylase of SIR2 family; NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form; Belongs to the sirtuin family. Class II subfamily. (296 aa)
SGUI_0998N-acetylglucosamine-6-phosphate deacetylase. (400 aa)
SGUI_1074Hypothetical protein. (245 aa)
SGUI_1075Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (278 aa)
ileSIsoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1141 aa)
clpXATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (425 aa)
SGUI_1122Membrane alanine aminopeptidase N. (852 aa)
SGUI_1161L-threonine 3-dehydrogenase. (350 aa)
SGUI_1210Methionine synthase, vitamin-B12 independent, putative. (331 aa)
mcaMycothiol S-conjugate amidase Mca; A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl-inositol) S- conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics; Belongs to the MshB deacetylase family. Mca subfamily. (353 aa)
SGUI_1326Hypothetical protein. (829 aa)
SGUI_1455Methylated-DNA--protein-cysteine methyltransferase. (516 aa)
ftsHCell division protein FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (665 aa)
SGUI_1539Fructose-bisphosphate aldolase class II; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (342 aa)
SGUI_1549Endonuclease IV. (353 aa)
SGUI_1686Phage-related protein. (171 aa)
SGUI_1713Formamidopyrimidine-DNA glycosylase; Belongs to the FPG family. (286 aa)
SGUI_1762Formamidopyrimidine-DNA glycosylase. (283 aa)
SGUI_1827Prolidase. (408 aa)
SGUI_2002Alcohol dehydrogenase. (331 aa)
SGUI_2069Threonine dehydrogenase and related Zn-dependent dehydrogenase. (404 aa)
SGUI_2071Hypothetical protein. (109 aa)
SGUI_2075Betaine--homocysteine S-methyltransferase. (361 aa)
SGUI_2146Threonine dehydrogenase and related Zn-dependent dehydrogenase. (339 aa)
SGUI_2169N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB. (265 aa)
SGUI_2195Allantoinase. (455 aa)
hutIImidazolonepropionase. (403 aa)
tadAtRNA-specific adenosine-34 deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. (174 aa)
SGUI_25885-methyltetrahydrofolate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1230 aa)
SGUI_2619Formaldehyde dehydrogenase MscR, NAD/mycothiol-dependent; S-nitrosomycothiol reductase MscR. (378 aa)
cysSCysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (488 aa)
SGUI_2760Diaminohydroxyphosphoribosylaminopyrimidine deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase. (417 aa)
SGUI_27623,4-dihydroxy-2-butanone 4-phosphate synthase; GTP cyclohydrolase II; In the N-terminal section; belongs to the DHBP synthase family. (412 aa)
SGUI_2805C4-type zinc finger protein, DksA/TraR family. (106 aa)
htpXPeptidase M48, Ste24p precursor; Belongs to the peptidase M48B family. (289 aa)
rpoCDNA-directed RNA polymerase beta' subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1308 aa)
SGUI_2943Carbonic anhydrase. (169 aa)
SGUI_2990N-acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha- D-glucopyranoside deacetylase MshB; Belongs to the MshB deacetylase family. (300 aa)
SGUI_3096Cytidine deaminase. (132 aa)
addAdenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. (380 aa)
SGUI_3123LmbE-like protein. (469 aa)
rnjRibonuclease J2 (endoribonuclease in RNA processing); An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay. (561 aa)
SGUI_3141Formamidopyrimidine-DNA glycosylase. (279 aa)
SGUI_3149Acetyl-coenzyme A carboxyl transferase beta chain. (657 aa)
SGUI_3204Circadian phase modifier. (234 aa)
gltXGlutamyl-tRNA synthetase; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (510 aa)
mutMFormamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. (297 aa)
Your Current Organism:
Serinicoccus sp. JLT9
NCBI taxonomy Id: 1758689
Other names: S. sp. JLT9
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