STRINGSTRING
SGUI_0095 SGUI_0095 SGUI_0130 SGUI_0130 SGUI_0143 SGUI_0143 SGUI_0200 SGUI_0200 SGUI_0310 SGUI_0310 SGUI_0311 SGUI_0311 SGUI_0312 SGUI_0312 SGUI_0313 SGUI_0313 arc arc SGUI_0333 SGUI_0333 pup pup pafA pafA SGUI_0345 SGUI_0345 SGUI_0346 SGUI_0346 SGUI_0352 SGUI_0352 SGUI_0369 SGUI_0369 SGUI_0376 SGUI_0376 gcvP gcvP gcvH gcvH SGUI_0399 SGUI_0399 SGUI_0437 SGUI_0437 pdxT pdxT SGUI_0455 SGUI_0455 SGUI_0457 SGUI_0457 SGUI_0465 SGUI_0465 SGUI_0486 SGUI_0486 SGUI_0500 SGUI_0500 SGUI_0510 SGUI_0510 SGUI_0550 SGUI_0550 dut dut SGUI_0600 SGUI_0600 SGUI_0609 SGUI_0609 nagB nagB anmK anmK murQ murQ SGUI_0654 SGUI_0654 SGUI_0681 SGUI_0681 SGUI_0713 SGUI_0713 SGUI_0714 SGUI_0714 SGUI_0715 SGUI_0715 SGUI_0719 SGUI_0719 SGUI_0723 SGUI_0723 SGUI_0748 SGUI_0748 SGUI_0760 SGUI_0760 SGUI_0783 SGUI_0783 SGUI_0784 SGUI_0784 SGUI_0789 SGUI_0789 gcvT gcvT SGUI_0929 SGUI_0929 SGUI_0939 SGUI_0939 SGUI_0998 SGUI_0998 SGUI_1001 SGUI_1001 SGUI_1023 SGUI_1023 kynA kynA SGUI_1052 SGUI_1052 SGUI_1065 SGUI_1065 SGUI_1066 SGUI_1066 SGUI_1067 SGUI_1067 pnp pnp SGUI_1161 SGUI_1161 SGUI_1169 SGUI_1169 rph rph SGUI_1187 SGUI_1187 SGUI_1222 SGUI_1222 SGUI_1232 SGUI_1232 SGUI_1233 SGUI_1233 SGUI_1238 SGUI_1238 SGUI_1243 SGUI_1243 SGUI_1315 SGUI_1315 SGUI_1322 SGUI_1322 SGUI_1332 SGUI_1332 SGUI_1401 SGUI_1401 SGUI_1437 SGUI_1437 SGUI_1504 SGUI_1504 SGUI_1505 SGUI_1505 SGUI_1511 SGUI_1511 SGUI_1568 SGUI_1568 SGUI_1622 SGUI_1622 SGUI_1629 SGUI_1629 SGUI_1652 SGUI_1652 SGUI_1763 SGUI_1763 SGUI_1803 SGUI_1803 SGUI_1816 SGUI_1816 SGUI_1827 SGUI_1827 SGUI_1870 SGUI_1870 SGUI_2007 SGUI_2007 SGUI_2030 SGUI_2030 SGUI_2031 SGUI_2031 SGUI_2032 SGUI_2032 SGUI_2069 SGUI_2069 SGUI_2125 SGUI_2125 SGUI_2146 SGUI_2146 SGUI_2172 SGUI_2172 SGUI_2193 SGUI_2193 SGUI_2194 SGUI_2194 SGUI_2195 SGUI_2195 SGUI_2196 SGUI_2196 SGUI_2205 SGUI_2205 SGUI_2215 SGUI_2215 SGUI_2227 SGUI_2227 ilvA ilvA SGUI_2299 SGUI_2299 SGUI_2323 SGUI_2323 SGUI_2331 SGUI_2331 hutU hutU hutI hutI SGUI_2353 SGUI_2353 dapA dapA SGUI_2473 SGUI_2473 arcA arcA SGUI_2579 SGUI_2579 dtd dtd SGUI_2619 SGUI_2619 SGUI_2620 SGUI_2620 SGUI_2676 SGUI_2676 SGUI_2690 SGUI_2690 SGUI_2696 SGUI_2696 SGUI_2721 SGUI_2721 SGUI_2738 SGUI_2738 SGUI_2775 SGUI_2775 SGUI_2810 SGUI_2810 SGUI_2851 SGUI_2851 SGUI_2936 SGUI_2936 xseB xseB xseA xseA SGUI_2971 SGUI_2971 SGUI_2973 SGUI_2973 SGUI_2991 SGUI_2991 SGUI_3016 SGUI_3016 SGUI_3023 SGUI_3023 SGUI_3096 SGUI_3096 deoC deoC SGUI_3206 SGUI_3206 SGUI_3208 SGUI_3208 SGUI_3219 SGUI_3219 SGUI_3254 SGUI_3254 SGUI_3268 SGUI_3268 SGUI_3279 SGUI_3279 glpK glpK SGUI_0074 SGUI_0074
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGUI_0095Deoxyguanosinetriphosphate triphosphohydrolase; Belongs to the dGTPase family. Type 2 subfamily. (425 aa)
SGUI_0130Hypothetical protein. (221 aa)
SGUI_0143Catalase; Belongs to the catalase family. (519 aa)
SGUI_0200Phosphopantothenoylcysteine decarboxylase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (415 aa)
SGUI_0310Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family. (383 aa)
SGUI_0311Carbon monoxide dehydrogenase small chain. (160 aa)
SGUI_0312Carbon monoxide dehydrogenase large chain. (839 aa)
SGUI_0313Carbon monoxide dehydrogenase medium chain. (284 aa)
arcBacterial proteasome-activating AAA-ATPase (PAN). (545 aa)
SGUI_0333Putative component of postulated heterodimer PafA-PafA'. (517 aa)
pupHypothetical protein; Protein modifier that is covalently attached to lysine residues of substrate proteins, thereby targeting them for proteasomal degradation. The tagging system is termed pupylation. Belongs to the prokaryotic ubiquitin-like protein family. (69 aa)
pafAPup ligase PafA, possible component of postulated heterodimer PafA-PafA; Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side- chain amino group of a substrate lysine. (461 aa)
SGUI_0345Putative helicase. (974 aa)
SGUI_0346Acetyl-CoA acetyltransferase; Belongs to the thiolase-like superfamily. Thiolase family. (404 aa)
SGUI_0352Lysine 2,3-aminomutase. (493 aa)
SGUI_0369Isochorismatase. (187 aa)
SGUI_0376Hypothetical protein. (172 aa)
gcvPGlycine dehydrogenase [decarboxylating] (glycine cleavage system P protein); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (961 aa)
gcvHGlycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (129 aa)
SGUI_0399Amidase; Belongs to the amidase family. (478 aa)
SGUI_0437Hydroxyacylglutathione hydrolase. (232 aa)
pdxTPyridoxine biosynthesis glutamine amidotransferase, glutaminase subunit; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (209 aa)
SGUI_0455HIT family protein. (179 aa)
SGUI_0457AclJ. (161 aa)
SGUI_0465Glyoxalase family protein. (297 aa)
SGUI_0486Glucose-fructose oxidoreductase. (396 aa)
SGUI_0500Threonine dehydrogenase and related Zn-dependent dehydrogenase. (335 aa)
SGUI_0510Glycogen debranching enzyme; Belongs to the glycosyl hydrolase 13 family. (709 aa)
SGUI_0550NAD-dependent dehydrogenase. (332 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (166 aa)
SGUI_0600Nitroreductase family protein. (207 aa)
SGUI_0609Aryldialkylphosphatase related protein. (419 aa)
nagBGlucosamine-6-phosphate deaminase; Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion; Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. NagB subfamily. (261 aa)
anmKAnhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (389 aa)
murQN-acetylmuramic acid 6-phosphate etherase; Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6-phosphate and D- lactate. (639 aa)
SGUI_0654Phospholipase/carboxylesterase. (122 aa)
SGUI_0681Threonine dehydrogenase and related Zn-dependent dehydrogenase. (393 aa)
SGUI_07132,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Belongs to the HpcH/HpaI aldolase family. (266 aa)
SGUI_07142-oxo-hepta-3-ene-1,7-dioic acid hydratase. (261 aa)
SGUI_0715Catechol 2,3-dioxygenase. (396 aa)
SGUI_0719Salicylate hydroxylase. (633 aa)
SGUI_0723Mandelate racemase/muconate lactonizing enzyme family protein. (388 aa)
SGUI_0748Carbon monoxide dehydrogenase large chain. (807 aa)
SGUI_0760ATP-dependent RNA helicase. (505 aa)
SGUI_0783Enoyl-CoA hydratase. (723 aa)
SGUI_07843-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (402 aa)
SGUI_0789ATP-dependent RNA helicase. (766 aa)
gcvTAminomethyltransferase (glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. (373 aa)
SGUI_0929Hypothetical protein. (298 aa)
SGUI_0939Oxidoreductase. (374 aa)
SGUI_0998N-acetylglucosamine-6-phosphate deacetylase. (400 aa)
SGUI_1001NAD-specific glutamate dehydrogenase, large form. (1599 aa)
SGUI_1023Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (413 aa)
kynATryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety. (312 aa)
SGUI_1052Hypothetical protein. (222 aa)
SGUI_1065Phenylacetate-CoA oxygenase, PaaI subunit. (254 aa)
SGUI_1066Phenylacetate-CoA oxygenase, PaaH subunit. (95 aa)
SGUI_1067Phenylacetate-CoA oxygenase, PaaG subunit. (342 aa)
pnpPolyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (827 aa)
SGUI_1161L-threonine 3-dehydrogenase. (350 aa)
SGUI_1169Nucleoside 5-triphosphatase RdgB (dHAPTP, dITP, XTP-specific); Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (210 aa)
rphRibonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. (264 aa)
SGUI_1187Fumarylacetoacetate hydrolase family protein. (259 aa)
SGUI_1222Glycogen debranching enzyme; Belongs to the glycosyl hydrolase 13 family. (712 aa)
SGUI_12323-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (401 aa)
SGUI_1233Exoenzymes regulatory protein AepA in lipid-linked oligosaccharide synthesis cluster. (505 aa)
SGUI_12383-hydroxyacyl-CoA dehydrogenase. (551 aa)
SGUI_1243Gamma-glutamyltranspeptidase. (508 aa)
SGUI_1315Glycerol-3-phosphate cytidylyltransferase. (444 aa)
SGUI_13223-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (456 aa)
SGUI_1332Nucleoside triphosphate pyrophosphohydrolase MazG. (338 aa)
SGUI_1401Gamma-glutamyltranspeptidase. (604 aa)
SGUI_1437Proline dehydrogenase (Proline oxidase). (321 aa)
SGUI_1504Zn-dependent hydrolase. (274 aa)
SGUI_1505Hypothetical protein. (286 aa)
SGUI_1511Cell division protein FtsH. (480 aa)
SGUI_1568Threonine dehydratase, catabolic. (332 aa)
SGUI_1622Purine nucleoside phosphorylase. (241 aa)
SGUI_16293-hydroxyacyl-CoA dehydrogenase. (541 aa)
SGUI_1652MOSC domain protein. (196 aa)
SGUI_1763Amidase. (451 aa)
SGUI_1803Methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. (306 aa)
SGUI_1816Putative secreted hydrolase. (344 aa)
SGUI_1827Prolidase. (408 aa)
SGUI_18706-phosphogluconate dehydrogenase, decarboxylating. (326 aa)
SGUI_2007Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (733 aa)
SGUI_2030Periplasmic aromatic aldehyde oxidoreductase, iron-sulfur subunit YagT. (193 aa)
SGUI_2031Periplasmic aromatic aldehyde oxidoreductase, FAD binding subunit YagS. (332 aa)
SGUI_2032Periplasmic aromatic aldehyde oxidoreductase, molybdenum binding subunit YagR. (712 aa)
SGUI_2069Threonine dehydrogenase and related Zn-dependent dehydrogenase. (404 aa)
SGUI_2125Alanine dehydrogenase; Belongs to the AlaDH/PNT family. (374 aa)
SGUI_2146Threonine dehydrogenase and related Zn-dependent dehydrogenase. (339 aa)
SGUI_2172Saccharopine dehydrogenase [NAD+, L-lysine-forming]. (344 aa)
SGUI_21932-hydroxy-3-oxopropionate reductase. (299 aa)
SGUI_2194Glyoxylate carboligase; Belongs to the TPP enzyme family. (587 aa)
SGUI_2195Allantoinase. (455 aa)
SGUI_2196RelE/StbE replicon stabilization toxin. (55 aa)
SGUI_2205Lactoylglutathione lyase. (152 aa)
SGUI_2215XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase). (275 aa)
SGUI_2227Flavodoxin reductases (ferredoxin-NADPH reductases) family 1. (272 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (425 aa)
SGUI_2299Heme oxygenase. (225 aa)
SGUI_2323Putative oxidoreductase YncB. (339 aa)
SGUI_2331Histidine ammonia-lyase. (538 aa)
hutUUrocanate hydratase; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. (552 aa)
hutIImidazolonepropionase. (403 aa)
SGUI_2353Putative aminomethyltransferase; Belongs to the GcvT family. (455 aa)
dapA4-hydroxy-tetrahydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (340 aa)
SGUI_2473Hypothetical protein. (110 aa)
arcAArginine deiminase. (415 aa)
SGUI_2579Hydrolase, putative isochorismatase. (177 aa)
dtdD-tyrosyl-tRNA(Tyr) deacylase; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA- based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D- aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl- tRNA entities in vivo and helps enforce protein L-homochirality. Belongs to the DTD family. (141 aa)
SGUI_2619Formaldehyde dehydrogenase MscR, NAD/mycothiol-dependent; S-nitrosomycothiol reductase MscR. (378 aa)
SGUI_2620Putative hydrolase in cluster with formaldehyde/S-nitrosomycothiol reductase MscR. (209 aa)
SGUI_2676Thiolase precursor. (389 aa)
SGUI_2690YoeB toxin protein. (122 aa)
SGUI_2696Nitrilotriacetate monooxygenase component B. (218 aa)
SGUI_2721Catalyzes the cleavage of p-aminobenzoyl-glutamate to p-aminobenzoate and glutamate, subunit A. (485 aa)
SGUI_2738Fumarylacetoacetase. (290 aa)
SGUI_2775Hypothetical protein. (438 aa)
SGUI_2810Beta-lactamase. (496 aa)
SGUI_28513-ketoacyl-CoA thiolase; Belongs to the thiolase-like superfamily. Thiolase family. (428 aa)
SGUI_2936Pullulanase; Belongs to the glycosyl hydrolase 13 family. (888 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (90 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (411 aa)
SGUI_2971Pyridoxal-dependent decarboxylase. (476 aa)
SGUI_2973Prophage Lp1 protein 5. (232 aa)
SGUI_2991Nitrilotriacetate monooxygenase component B. (170 aa)
SGUI_3016Putative ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. (496 aa)
SGUI_3023NADH pyrophosphatase. (313 aa)
SGUI_3096Cytidine deaminase. (132 aa)
deoCDeoxyribose-phosphate aldolase; Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5- phosphate; Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily. (258 aa)
SGUI_32066-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (494 aa)
SGUI_3208Uronate isomerase. (470 aa)
SGUI_3219Hypothetical protein. (69 aa)
SGUI_3254Putative oxidoreductase. (352 aa)
SGUI_3268Aminopeptidase YpdF (MP-, MA-, MS-, AP-, NP- specific). (367 aa)
SGUI_3279Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (242 aa)
glpKGlycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family. (512 aa)
SGUI_0074Phosphoenolpyruvate-dihydroxyacetone phosphotransferase, subunit DhaM; DHA-specific IIA component; DHA-specific phosphocarrier protein HPr; DHA-specific EI component; Belongs to the PEP-utilizing enzyme family. (826 aa)
Your Current Organism:
Serinicoccus sp. JLT9
NCBI taxonomy Id: 1758689
Other names: S. sp. JLT9
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