(67 nodes) Mixed, incl. Degradation of aromatic compounds, and Carnitine metabolic process network (Sphingopyxis sp. HIX)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KTE42990.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (409 aa)
	KTE42991.1	(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
	KTE40393.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (103 aa)
	KTE40394.1	P-cresol methylhydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
	KTE40395.1	FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
	KTE40396.1	Ubiquinone biosynthesis protein UbiD; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UbiD family. (492 aa)
	KTE40397.1	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (485 aa)
	KTE40398.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
	KTE40399.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
	ubiX	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN; Belongs to the UbiX/PAD1 family. (206 aa)
	KTE40446.1	2-dehydro-3-deoxyglucarate aldolase; Cleaves 5-dehydro-4-deoxy-glucarate and 2-dehydro-3-deoxy-D-glucarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HpcH/HpaI aldolase family. (254 aa)
	KTE40400.1	2-oxo-hepta-3-ene-1,7-dioate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (266 aa)
	KTE40447.1	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
	KTE40401.1	Aromatic-ring-hydroxylating dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (165 aa)
	KTE40402.1	(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (391 aa)
	KTE40403.1	Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (338 aa)
	KTE40404.1	1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
	KTE40405.1	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (501 aa)
	KTE40407.1	4-oxalocrotonate tautomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (70 aa)
	KTE40408.1	4-oxalocrotonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (256 aa)
	KTE40409.1	4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (347 aa)
	KTE40410.1	Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (311 aa)
	KTE40411.1	2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (267 aa)
	KTE40449.1	2-hydroxymuconic semialdehyde dehydrogenase; Catalyzes the formation of betaine from betaine aldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
	KTE40413.1	Catechol 2,3-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
	KTE40414.1	2-hydroxy-6-oxo-2,4-heptadienoate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
	KTE40417.1	Benzene 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
	KTE40418.1	Benzoate 1,2-dioxygenase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (470 aa)
	KTE40419.1	2,3-dihydroxybiphenyl 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
	KTE40450.1	Anthranilate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
	KTE40451.1	Rieske (2Fe-2S) protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (404 aa)
	KTE40421.1	Disulfide bond formation protein DsbA; Derived by automated computational analysis using gene prediction method: Protein Homology. (196 aa)
	KTE40423.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
	KTE40424.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
	KTE40425.1	Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
	KTE40426.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PdxA family. (335 aa)
	KTE40427.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (182 aa)
	KTE40453.1	(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
	KTE40428.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (452 aa)
	KTE40429.1	Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (485 aa)
	KTE40454.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (645 aa)
	KTE40430.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
	KTE40431.1	(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
	KTE40432.1	Bleomycin resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
	KTE40433.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
	KTE39309.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (719 aa)
	KTE39311.1	Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (178 aa)
	KTE39312.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (152 aa)
	KTE39313.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
	KTE39314.1	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
	KTE39315.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (151 aa)
	KTE39316.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (177 aa)
	KTE39317.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 4-oxalocrotonate tautomerase family. (65 aa)
	KTE39318.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (298 aa)
	KTE39338.1	2-hydroxymuconic semialdehyde dehydrogenase; Catalyzes the formation of betaine from betaine aldehyde; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
	KTE39320.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
	KTE39321.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
	KTE39339.1	Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
	KTE39322.1	4-oxalocrotonate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (251 aa)
	KTE39324.1	3-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (248 aa)
	KTE39325.1	4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family. (340 aa)
	KTE39326.1	Acetaldehyde dehydrogenase (acetylating); Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds. (318 aa)
	KTE39327.1	2-keto-4-pentenoate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
	KTE33753.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (401 aa)
	KTE30870.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
	KTE30872.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
	KTE30873.1	2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (290 aa)

Your Current Organism:

Sphingopyxis sp. HIX

NCBI taxonomy Id: 1759074
Other names: S. sp. HIX

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KTE30870.1	KTE30872.1	ATE62_20300	ATE62_20310	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.790
KTE30870.1	KTE30873.1	ATE62_20300	ATE62_20315	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.697
KTE30870.1	KTE33753.1	ATE62_20300	ATE62_16690	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.482
KTE30870.1	KTE39312.1	ATE62_20300	ATE62_09590	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.471
KTE30870.1	KTE39321.1	ATE62_20300	ATE62_09640	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.412
KTE30870.1	KTE39339.1	ATE62_20300	ATE62_09645	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.422
KTE30870.1	KTE40395.1	ATE62_20300	ATE62_07755	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	FAD-linked oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.538
KTE30870.1	KTE40398.1	ATE62_20300	ATE62_07770	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.503
KTE30870.1	KTE40400.1	ATE62_20300	ATE62_07790	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	2-oxo-hepta-3-ene-1,7-dioate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.430
KTE30870.1	KTE40402.1	ATE62_20300	ATE62_07805	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.574
KTE30870.1	KTE40413.1	ATE62_20300	ATE62_07870	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Catechol 2,3-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.662
KTE30870.1	KTE40418.1	ATE62_20300	ATE62_07895	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Benzoate 1,2-dioxygenase large subunit; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.494
KTE30870.1	KTE40419.1	ATE62_20300	ATE62_07900	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	2,3-dihydroxybiphenyl 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.450
KTE30870.1	KTE40427.1	ATE62_20300	ATE62_07955	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.507
KTE30870.1	KTE40431.1	ATE62_20300	ATE62_07985	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
KTE30870.1	KTE40432.1	ATE62_20300	ATE62_07990	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Bleomycin resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.405
KTE30870.1	KTE40433.1	ATE62_20300	ATE62_07995	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.511
KTE30870.1	KTE40450.1	ATE62_20300	ATE62_07910	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Anthranilate 1,2-dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.464
KTE30870.1	KTE40451.1	ATE62_20300	ATE62_07915	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Rieske (2Fe-2S) protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.629
KTE30870.1	KTE40453.1	ATE62_20300	ATE62_07960	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	(2Fe-2S)-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.604