(6 nodes) Mixed, incl. Coenzyme A biosynthesis, and Biotin/lipoate A/B protein ligase family network (Sphingopyxis sp. HIX)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	KTE31838.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (125 aa)
	KTE31857.1	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
	coaX	Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (260 aa)
	KTE31846.1	MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
	KTE31847.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (86 aa)
	coaD	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (168 aa)

Your Current Organism:

Sphingopyxis sp. HIX

NCBI taxonomy Id: 1759074
Other names: S. sp. HIX

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
KTE31838.1	KTE31846.1	ATE62_18960	ATE62_19005	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.741
KTE31838.1	KTE31847.1	ATE62_18960	ATE62_19010	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.720
KTE31838.1	KTE31857.1	ATE62_18960	ATE62_18995	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.741
KTE31838.1	coaX	ATE62_18960	ATE62_19000	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.	0.741
KTE31846.1	KTE31838.1	ATE62_19005	ATE62_18960	MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.741
KTE31846.1	KTE31847.1	ATE62_19005	ATE62_19010	MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.826
KTE31846.1	KTE31857.1	ATE62_19005	ATE62_18995	MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
KTE31846.1	coaX	ATE62_19005	ATE62_19000	MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.	0.841
KTE31847.1	KTE31838.1	ATE62_19010	ATE62_18960	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.720
KTE31847.1	KTE31846.1	ATE62_19010	ATE62_19005	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.826
KTE31847.1	KTE31857.1	ATE62_19010	ATE62_18995	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.826
KTE31847.1	coaX	ATE62_19010	ATE62_19000	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.	0.826
KTE31857.1	KTE31838.1	ATE62_18995	ATE62_18960	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.741
KTE31857.1	KTE31846.1	ATE62_18995	ATE62_19005	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	MBL fold metallo-hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.841
KTE31857.1	KTE31847.1	ATE62_18995	ATE62_19010	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.826
KTE31857.1	coaD	ATE62_18995	ATE62_22620	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	0.558
KTE31857.1	coaX	ATE62_18995	ATE62_19000	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.	0.919
coaD	KTE31857.1	ATE62_22620	ATE62_18995	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	Biotin--protein ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.558
coaD	coaX	ATE62_22620	ATE62_19000	Phosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family.	Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.	0.935
coaX	KTE31838.1	ATE62_19000	ATE62_18960	Type III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	0.741