STRINGSTRING
KTE46405.1 KTE46405.1 KTE46461.1 KTE46461.1 KTE46462.1 KTE46462.1 KTE45730.1 KTE45730.1 KTE45038.1 KTE45038.1 KTE44296.1 KTE44296.1 KTE43019.1 KTE43019.1 KTE42374.1 KTE42374.1 KTE42376.1 KTE42376.1 dnaJ dnaJ dnaK dnaK clpX clpX clpP clpP KTE41936.1 KTE41936.1 KTE41459.1 KTE41459.1 hslV hslV hrcA hrcA grpE grpE KTE40759.1 KTE40759.1 katG katG KTE39549.1 KTE39549.1 clpS clpS clpB clpB KTE36541.1 KTE36541.1 KTE36542.1 KTE36542.1 lon lon groEL groEL groS groS KTE32773.1 KTE32773.1 KTE32411.1 KTE32411.1 clpA clpA hfq hfq
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KTE46405.1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (191 aa)
KTE46461.1ATP-dependent protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
KTE46462.1Co-chaperone YbbN; Derived by automated computational analysis using gene prediction method: Protein Homology. (303 aa)
KTE45730.1Heat-shock protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the small heat shock protein (HSP20) family. (151 aa)
KTE45038.1Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
KTE44296.1Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (204 aa)
KTE43019.1Molecular chaperone HscC; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the heat shock protein 70 family. (568 aa)
KTE42374.1Catalase; Serves to protect cells from the toxic effects of hydrogen peroxide. (716 aa)
KTE42376.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
dnaJChaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (374 aa)
dnaKMolecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (635 aa)
clpXATP-dependent Clp protease ATP-binding subunit ClpX; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP. (423 aa)
clpPATP-dependent Clp protease proteolytic subunit; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (216 aa)
KTE41936.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thioredoxin family. (106 aa)
KTE41459.1ATP-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. (433 aa)
hslVATP-dependent protease subunit HslV; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (188 aa)
hrcAHeat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. (347 aa)
grpEMolecular chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP [...] (184 aa)
KTE40759.1Molecular chaperone DnaJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
katGHydroperoxidase; Bifunctional enzyme with both catalase and broad-spectrum peroxidase activity; Belongs to the peroxidase family. Peroxidase/catalase subfamily. (729 aa)
KTE39549.1Thioredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology. (296 aa)
clpSATP-dependent Clp protease adaptor ClpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family. (120 aa)
clpBATP-dependent chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (859 aa)
KTE36541.1Alkyl hydroperoxide reductase; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. (187 aa)
KTE36542.1Alkyl hydroperoxide reductase subunit F; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
lonDNA-binding protein; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (798 aa)
groELMolecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (547 aa)
groSMolecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (95 aa)
KTE32773.1Thioredoxin reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
KTE32411.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (510 aa)
clpAATPase and specificity subunit of the ClpA-ClpP ATP dependent serine protease; directs protease to specific substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ClpA/ClpB family. (778 aa)
hfqRNA-binding protein hfq; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. (163 aa)
Your Current Organism:
Sphingopyxis sp. HIX
NCBI taxonomy Id: 1759074
Other names: S. sp. HIX
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