STRINGSTRING
KTE38355.1 KTE38355.1 KTE44981.1 KTE44981.1 KTE45032.1 KTE45032.1 leuD leuD leuC leuC leuD-2 leuD-2 KTE31880.1 KTE31880.1 leuB leuB KTE24946.1 KTE24946.1 leuC-2 leuC-2 KTE34336.1 KTE34336.1 ilvD ilvD KTE38069.1 KTE38069.1 leuA leuA ilvC ilvC KTE38028.1 KTE38028.1 KTE38027.1 KTE38027.1 KTE38403.1 KTE38403.1 KTE38419.1 KTE38419.1 KTE43595.1 KTE43595.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
KTE38355.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (352 aa)
KTE44981.1Aminotransferase class IV; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
KTE45032.1Pyridoxal-5'-phosphate-dependent protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
leuD3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (196 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (476 aa)
leuD-23-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (194 aa)
KTE31880.1Threonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
leuB3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. (351 aa)
KTE24946.1Acetolactate synthase; Catalyzes the condensation of two pyruvates to form acetolactate, implicated in pH homeostasis via the acetoin-2,3-butanediol pathway or in valine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (548 aa)
leuC-2Isopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (473 aa)
KTE34336.1Catalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (361 aa)
ilvDDihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the IlvD/Edd family. (620 aa)
KTE38069.1Amino acid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (349 aa)
leuA2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (554 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (344 aa)
KTE38028.1Acetolactate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology. (171 aa)
KTE38027.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
KTE38403.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
KTE38419.13-isopropylmalate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (346 aa)
KTE43595.1Acetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TPP enzyme family. (610 aa)
Your Current Organism:
Sphingopyxis sp. HIX
NCBI taxonomy Id: 1759074
Other names: S. sp. HIX
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