STRINGSTRING
VRK_08440 VRK_08440 VRK_41790 VRK_41790 ilvE-2 ilvE-2 ilvD ilvD VRK_40530 VRK_40530 coaA coaA VRK_37440 VRK_37440 VRK_37390 VRK_37390 VRK_33110 VRK_33110 ilvE ilvE VRK_28720 VRK_28720 VRK_24600 VRK_24600 VRK_23670 VRK_23670 VRK_20970 VRK_20970 VRK_19770 VRK_19770 VRK_15680 VRK_15680 VRK_13690 VRK_13690 VRK_10970 VRK_10970 VRK_09950 VRK_09950 VRK_41800 VRK_41800 panB panB ilvC ilvC VRK_00640 VRK_00640 VRK_00750 VRK_00750 VRK_00830 VRK_00830 coaD coaD VRK_04000 VRK_04000 VRK_04010 VRK_04010 acpS acpS VRK_04360 VRK_04360 yacG yacG coaE coaE panC panC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
VRK_08440Phage integrase; Belongs to the 'phage' integrase family. (162 aa)
VRK_41790Acetolactate synthase 2 regulatory subunit. (94 aa)
ilvE-2Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (313 aa)
ilvDDihydroxy-acid dehydratase; Belongs to the IlvD/Edd family. (613 aa)
VRK_40530Hypothetical protein. (524 aa)
coaAPantothenate kinase. (307 aa)
VRK_37440Phage integrase family protein. (146 aa)
VRK_37390Phage integrase family protein. (359 aa)
VRK_33110Acyl carrier protein phosphodiesterase. (202 aa)
ilvEilvE3 protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (324 aa)
VRK_28720Hypothetical protein. (112 aa)
VRK_24600Acetolactate synthase. (513 aa)
VRK_23670Hypothetical protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid. (298 aa)
VRK_20970Hypothetical protein; Belongs to the P-Pant transferase superfamily. (238 aa)
VRK_19770Integrase, putative; Belongs to the 'phage' integrase family. (400 aa)
VRK_15680Hypothetical protein; Belongs to the P-Pant transferase superfamily. (244 aa)
VRK_13690Glutamate decarboxylase eukaryotic type. (550 aa)
VRK_10970Hypothetical protein. (128 aa)
VRK_09950Alpha-acetolactate synthase; Belongs to the TPP enzyme family. (568 aa)
VRK_41800Acetolactate synthase II, large subunit. (548 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (264 aa)
ilvCHypothetical protein; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (494 aa)
VRK_00640Phage integrase family site specific recombinase; Belongs to the 'phage' integrase family. (279 aa)
VRK_00750Hypothetical protein; Belongs to the 'phage' integrase family. (346 aa)
VRK_00830Phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (164 aa)
VRK_04000Acetolactate synthase large subunit. (573 aa)
VRK_04010Acetolactate synthase small subunit. (164 aa)
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (129 aa)
VRK_04360Nucleoside triphosphate pyrophosphohydrolase MazG. (271 aa)
yacGZinc-binding protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. (67 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (202 aa)
panCPantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (303 aa)
Your Current Organism:
Vibrio sp. MEBiC08052
NCBI taxonomy Id: 1761910
Other names: V. sp. MEBiC08052
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