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| | ahcY | S-adenosylhomocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (466 aa) |
| | cysJ | Sulfite reductase (NADPH) flavoprotein alpha-component; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component. (589 aa) |
| | Atu0267 | Hypothetical protein. (117 aa) |
| | Atu0268 | Hypothetical protein. (80 aa) |
| | xseA | Exodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (532 aa) |
| | pfs | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase. (212 aa) |
| | cysK | Cysteine synthase. (322 aa) |
| | metK | S-adenosylmethionine synthetase; Belongs to the AdoMet synthase family. (420 aa) |
| | metZ | O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (394 aa) |
| | Atu0746 | Conserved hypothetical protein; Belongs to the pirin family. (307 aa) |
| | xseB | Exodeoxyribonuclease small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (84 aa) |
| | Atu0748 | Deacetylase. (311 aa) |
| | bioY | Biotin synthesis BioY protein. (187 aa) |
| | Atu0750 | ABC transporter, membrane spanning protein. (210 aa) |
| | Atu0751 | ABC transporter, nucleotide binding/ATPase protein (cobalt). (226 aa) |
| | Atu0752 | Conserved hypothetical protein. (398 aa) |
| | gpmB | Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. (196 aa) |
| | Atu0759 | Conserved hypothetical protein. (149 aa) |
| | cysN | Sulfate adenylate transferase, subunit 1; May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. (494 aa) |
| | cysD-2 | Sulfate adenylate transferase, subunit 2. (317 aa) |
| | cysH | Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. (253 aa) |
| | Atu0820 | ABC transporter, substrate binding protein (sulfate). (341 aa) |
| | cysT | ABC transporter, membrane spanning protein; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (285 aa) |
| | Atu0822 | ABC transporter, membrane spanning protein. (290 aa) |
| | cysA1 | ABC transporter, nucleotide binding/ATPase protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (346 aa) |
| | cysS | cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (461 aa) |
| | hemB | Delta-aminolevulinic acid dehydratase; Belongs to the ALAD family. (337 aa) |
| | Atu1215 | Thiosulfate sulfurtransferase. (473 aa) |
| | alaS | alanyl-tRNA synthetase. (245 aa) |
| | cysK-2 | Cysteine synthase. (345 aa) |
| | cysD | O-acetylhomoserine sulfhydrylase. (427 aa) |
| | aspB-2 | Aspartate transaminase. (387 aa) |
| | serA | Phosphoglycerate dehydrogenase. (328 aa) |
| | metF | Methylenetetrahydrofolate reductase. (306 aa) |
| | Atu1453 | Conserved hypothetical protein. (195 aa) |
| | cysG | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (487 aa) |
| | Atu1455 | Conserved hypothetical protein. (104 aa) |
| | cysI | Sulfite reductase (NADPH) hemoprotein beta-component. (556 aa) |
| | Atu1457 | Conserved hypothetical protein. (168 aa) |
| | mvrA | Ferredoxin NADP+ reductase. (270 aa) |
| | cobP | Bifunctional adenosylcobalamin biosynthesis protein cobP; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (173 aa) |
| | cysE | Serine acetyltransferase. (200 aa) |
| | cysE-2 | Serine acetyltransferase. (274 aa) |
| | metC | Cystathionine beta lyase. (395 aa) |
| | hemN-2 | Oxygen-independent coproporphyrinogen III oxidase; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (449 aa) |
| | Atu1654 | Nitroreductase. (228 aa) |
| | cobT | Cobyrinic acid synthase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (344 aa) |
| | cobS | Cobalamin biosynthesis protein; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (261 aa) |
| | metF-3 | Methylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (296 aa) |
| | metH | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1257 aa) |
| | hemF | Coproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (303 aa) |
| | hemA | 5-aminolevulinate synthase. (347 aa) |
| | hemC | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (309 aa) |
| | hem4 | Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III. (246 aa) |
| | metA | Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (308 aa) |
| | cobB | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (438 aa) |
| | cobA | uroporphyrin-III C-methyltransferase; Belongs to the precorrin methyltransferase family. (262 aa) |
| | cbiD | Cobalamin biosynthetic protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (378 aa) |
| | cobM | Precorrin-4 C11-methyltransferase; Belongs to the precorrin methyltransferase family. (257 aa) |
| | chiG | Cobalamin biosynthesis protein. (145 aa) |
| | cobL | Precorrin-6y methyltransferase. (419 aa) |
| | cobK | Precorrin-6x reductase. (260 aa) |
| | cobJ | precorrin-3B C17-methyltransferase. (253 aa) |
| | cobI | Precorrin-2 C20 methyltransferase; Belongs to the precorrin methyltransferase family. (255 aa) |
| | cbiC | precorrin-8X methylmutase. (210 aa) |
| | cobG | Cobalamin biosynthesis associated protein. (451 aa) |
| | cobN | Cobaltochelatase subunit. (1116 aa) |
| | cobW | Cobalamin synthesis protein. (345 aa) |
| | Atu2806 | Conserved hypothetical protein. (152 aa) |
| | cobO | cob(I)alamin adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (205 aa) |
| | cbiP | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (485 aa) |
| | cobD | Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (321 aa) |
| | cobC | Cobalamin biosynthetic protein. (348 aa) |
| | Atu2834 | Conserved hypothetical protein. (165 aa) |
| | hemE | Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (344 aa) |
| | cysA2 | ABC transporter, nucleotide binding/ATPase protein; Part of the ABC transporter complex CysAWTP involved in sulfate/thiosulfate import. Responsible for energy coupling to the transport system. (341 aa) |
| | Atu3502 | ABC transporter, membrane spanning protein. (295 aa) |
| | Atu3503 | ABC transporter, membrane spanning protein; Part of the ABC transporter complex (TC 3.A.1.6.1) involved in sulfate/thiosulfate import; Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily. (277 aa) |
| | Atu3504 | ABC transporter, substrate binding protein (sulfate). (328 aa) |
| | Atu3593 | Conserved hypothetical protein; Belongs to the Cob(I)alamin adenosyltransferase family. (192 aa) |
| | cobT-2 | Cobyrinic acid synthase. (634 aa) |
| | cobS-2 | Cobalamin biosynthesis protein. (329 aa) |
| | serA-2 | D-3-phosphoglycerate dehydrogenase; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (531 aa) |
| | serC | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (392 aa) |
| | mdeA-2 | Methionine gamma-lyase. (427 aa) |
| | metE | 5-methyltetrahydropteroyltriglutamate- homocysteine methyltransferase. (342 aa) |
| | cysG-2 | Siroheme synthase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family. (475 aa) |
| | metN | ABC transporter, nucleotide binding/ATPase protein; Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system. (346 aa) |
| | Atu4488 | ABC transporter, membrane spanning protein. (222 aa) |
| | Atu4489 | Outer membrane lipoprotein. (259 aa) |
| | hemL | Glutamate-1-semialdehyde 2,1-aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (467 aa) |
