STRINGSTRING
APZ41699.1 APZ41699.1 APZ41700.1 APZ41700.1 APZ41701.1 APZ41701.1 APZ41702.1 APZ41702.1 APZ41703.1 APZ41703.1 rbsK rbsK APZ41705.1 APZ41705.1 glgA glgA zwf zwf pgi pgi APZ42182.1 APZ42182.1 fbp fbp pfp pfp APZ42321.1 APZ42321.1 eno eno APZ42323.1 APZ42323.1 BW247_04445 BW247_04445 APZ42438.1 APZ42438.1 APZ42439.1 APZ42439.1 gpmA gpmA BW247_05855 BW247_05855 pfkA pfkA APZ43218.1 APZ43218.1 APZ43219.1 APZ43219.1 glgC glgC glgB glgB xylB xylB APZ43279.1 APZ43279.1 ligA ligA zipA zipA APZ43284.1 APZ43284.1 eno-2 eno-2 APZ43325.1 APZ43325.1 zwf-2 zwf-2 APZ43414.1 APZ43414.1 rpiA rpiA APZ43660.1 APZ43660.1 APZ44690.1 APZ44690.1 APZ43685.1 APZ43685.1 APZ43829.1 APZ43829.1 APZ43830.1 APZ43830.1 APZ43831.1 APZ43831.1 tpiA tpiA APZ43881.1 APZ43881.1 APZ43937.1 APZ43937.1 APZ43938.1 APZ43938.1 APZ43940.1 APZ43940.1 APZ43941.1 APZ43941.1 APZ43946.1 APZ43946.1 APZ43983.1 APZ43983.1 tal tal pgl pgl APZ44125.1 APZ44125.1 APZ44188.1 APZ44188.1 APZ44198.1 APZ44198.1 APZ44269.1 APZ44269.1 APZ44270.1 APZ44270.1 pgk pgk APZ44272.1 APZ44272.1 APZ44273.1 APZ44273.1 APZ44404.1 APZ44404.1 APZ44406.1 APZ44406.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APZ41699.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (61 aa)
APZ41700.1Ribose ABC transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (145 aa)
APZ41701.1Inner-membrane translocator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the binding-protein-dependent transport system permease family. (329 aa)
APZ41702.1ABC transporter ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
APZ41703.1D-ribose-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
rbsKRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (297 aa)
APZ41705.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (327 aa)
glgAStarch synthase; Synthesizes alpha-1,4-glucan chains using ADP-glucose. (483 aa)
zwfGlucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (504 aa)
pgiGlucose-6-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GPI family. (549 aa)
APZ42182.1Phosphoenolpyruvate--protein phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the PEP-utilizing enzyme family. (755 aa)
fbpFructose-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FBPase class 1 family. (336 aa)
pfp6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions. (428 aa)
APZ42321.1Glycogen debranching enzyme GlgX; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glycosyl hydrolase 13 family. (694 aa)
enoPhosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (432 aa)
APZ42323.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (479 aa)
BW247_04445Hypothetical protein; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
APZ42438.1Aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
APZ42439.1Alpha-glucan phosphorylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (843 aa)
gpmA2,3-bisphosphoglycerate-dependent phosphoglycerate mutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (245 aa)
BW247_05855Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (543 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (379 aa)
APZ43218.14-alpha-glucanotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (486 aa)
APZ43219.1Glycoside hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (566 aa)
glgCGlucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family. (421 aa)
glgB1,4-alpha-glucan branching enzyme; Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position; Belongs to the glycosyl hydrolase 13 family. GlgB subfamily. (728 aa)
xylBAAA family ATPase; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (485 aa)
APZ43279.1Class II aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (215 aa)
ligADNA ligase (NAD(+)) LigA; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. (690 aa)
zipAHypothetical protein; Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins. (874 aa)
APZ43284.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (442 aa)
eno-2Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis. (425 aa)
APZ43325.1Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
zwf-2Glucose-6-phosphate dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. (498 aa)
APZ43414.16-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. (355 aa)
rpiARibose 5-phosphate isomerase A; Catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate. (218 aa)
APZ43660.1Phosphoenolpyruvate synthase regulatory protein; Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation/dephosphorylation. (274 aa)
APZ44690.1Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. (792 aa)
APZ43685.1Carbohydrate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the carbohydrate kinase PfkB family. (321 aa)
APZ43829.1Endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
APZ43830.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
APZ43831.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (708 aa)
tpiATriose-phosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (248 aa)
APZ43881.1Phosphomannomutase/phosphoglucomutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
APZ43937.1PTS sugar transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (155 aa)
APZ43938.1HPr(Ser) kinase/phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the HPrK/P family. (314 aa)
APZ43940.1PTS fructose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
APZ43941.1Phosphocarrier protein HPr; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
APZ43946.1Phosphoenolpyruvate--protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (581 aa)
APZ43983.1Alkaline invertase; Derived by automated computational analysis using gene prediction method: Protein Homology. (459 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (374 aa)
pgl6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (242 aa)
APZ44125.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family. (344 aa)
APZ44188.1Glycogen phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (829 aa)
APZ44198.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (193 aa)
APZ44269.1Fructose-1,6-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis. (354 aa)
APZ44270.1Pyruvate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pyruvate kinase family. (483 aa)
pgkPhosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (392 aa)
APZ44272.1Type I glyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (335 aa)
APZ44273.1Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (661 aa)
APZ44404.1RpiR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
APZ44406.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
Your Current Organism:
Acidihalobacter ferrooxidans
NCBI taxonomy Id: 1765967
Other names: A. ferrooxidans
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