STRINGSTRING
lspA lspA murJ murJ APZ41743.1 APZ41743.1 APZ41744.1 APZ41744.1 APZ44445.1 APZ44445.1 APZ41745.1 APZ41745.1 APZ41746.1 APZ41746.1 APZ44446.1 APZ44446.1 murE murE BW247_01860 BW247_01860 APZ42028.1 APZ42028.1 APZ42029.1 APZ42029.1 APZ42030.1 APZ42030.1 APZ42034.1 APZ42034.1 mrdB mrdB APZ42109.1 APZ42109.1 APZ42110.1 APZ42110.1 APZ42134.1 APZ42134.1 mraZ mraZ rsmH rsmH ftsL ftsL ftsI ftsI murE-2 murE-2 murF murF mraY mraY murD murD ftsW ftsW murC murC murB murB ddl ddl ftsQ ftsQ ftsA ftsA ftsZ ftsZ APZ42269.1 APZ42269.1 APZ42335.1 APZ42335.1 APZ42751.1 APZ42751.1 APZ43067.1 APZ43067.1 APZ43208.1 APZ43208.1 APZ43210.1 APZ43210.1 APZ43211.1 APZ43211.1 APZ43213.1 APZ43213.1 ftsB ftsB APZ43450.1 APZ43450.1 APZ43451.1 APZ43451.1 APZ44678.1 APZ44678.1 APZ43674.1 APZ43674.1 lgt-2 lgt-2 APZ43698.1 APZ43698.1 APZ43699.1 APZ43699.1 APZ43916.1 APZ43916.1 minC minC APZ43978.1 APZ43978.1 minE minE APZ43980.1 APZ43980.1 lipA lipA lipB lipB APZ44729.1 APZ44729.1 APZ44113.1 APZ44113.1 APZ44114.1 APZ44114.1 rlpA rlpA APZ44116.1 APZ44116.1 rlpA-2 rlpA-2 APZ44730.1 APZ44730.1 mrdB-2 mrdB-2 mrdA mrdA APZ44127.1 APZ44127.1 APZ44741.1 APZ44741.1 anmK anmK APZ44195.1 APZ44195.1 APZ44308.1 APZ44308.1 ftsE ftsE APZ44753.1 APZ44753.1 APZ44319.1 APZ44319.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
lspASignal peptidase II; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. (161 aa)
murJMurein biosynthesis integral membrane protein MurJ; Involved in peptidoglycan biosynthesis. Transports lipid- linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane. (517 aa)
APZ41743.1DJ-1 family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (176 aa)
APZ41744.1Peptidase S41; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S41A family. (443 aa)
APZ44445.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (381 aa)
APZ41745.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
APZ41746.1Sulfurtransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
APZ44446.1Glutaredoxin 3; Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins. (88 aa)
murEHypothetical protein; Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. (483 aa)
BW247_01860Transposase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
APZ42028.1Rod shape-determining protein MreD; Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins. Belongs to the MreD family. (162 aa)
APZ42029.1Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape. (301 aa)
APZ42030.1Rod shape-determining protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
APZ42034.1Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (689 aa)
mrdBRod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (370 aa)
APZ42109.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
APZ42110.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (134 aa)
APZ42134.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (639 aa)
mraZCell division/cell wall cluster transcriptional repressor MraZ; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the MraZ family. (150 aa)
rsmH16S rRNA (cytosine(1402)-N(4))-methyltransferase; Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA. (311 aa)
ftsLCell division protein FtsL; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (85 aa)
ftsIHypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (573 aa)
murE-2UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. (484 aa)
murFHypothetical protein; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. (456 aa)
mraYphospho-N-acetylmuramoyl-pentapeptide- transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. (361 aa)
murDUDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (451 aa)
ftsWPutative lipid II flippase FtsW; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. (417 aa)
murCUndecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Cell wall formation; Belongs to the MurCDEF family. (473 aa)
murBUDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. (306 aa)
ddlD-alanine--D-alanine ligase; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family. (314 aa)
ftsQHypothetical protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. (270 aa)
ftsACell division protein FtsA; Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring. Belongs to the FtsA/MreB family. (413 aa)
ftsZCell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity. (382 aa)
APZ42269.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
APZ42335.1Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (842 aa)
APZ42751.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
APZ43067.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
APZ43208.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
APZ43210.1D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
APZ43211.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (129 aa)
APZ43213.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (203 aa)
ftsBCell division protein FtsB; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. (108 aa)
APZ43450.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
APZ43451.1Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (785 aa)
APZ44678.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (395 aa)
APZ43674.1NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1589 aa)
lgt-2Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. (264 aa)
APZ43698.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (157 aa)
APZ43699.1rRNA large subunit methyltransferase I; Derived by automated computational analysis using gene prediction method: Protein Homology. (399 aa)
APZ43916.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (114 aa)
minCHypothetical protein; Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization; Belongs to the MinC family. (248 aa)
APZ43978.1Septum site-determining protein MinD; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
minECell division topological specificity factor MinE; Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell. (87 aa)
APZ43980.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (79 aa)
lipALipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (318 aa)
lipBOctanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. (215 aa)
APZ44729.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0250 family. (101 aa)
APZ44113.1D-amino acid aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (294 aa)
APZ44114.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (398 aa)
rlpAHypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (249 aa)
APZ44116.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (401 aa)
rlpA-2Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. (249 aa)
APZ44730.1Lytic murein transglycosylase B; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
mrdB-2Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. (360 aa)
mrdAPenicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (671 aa)
APZ44127.1Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (390 aa)
APZ44741.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (457 aa)
anmKanhydro-N-acetylmuramic acid kinase; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (378 aa)
APZ44195.1Glycosyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
APZ44308.116S rRNA (guanine(966)-N(2))-methyltransferase RsmD; Specifically methylates the guanine in position 966 of 16S rRNA in the assembled 30S particle; Belongs to the methyltransferase superfamily. RsmD family. (199 aa)
ftsECell division ATP-binding protein FtsE; Part of the ABC transporter FtsEX involved in cellular division. (227 aa)
APZ44753.1Cell division protein FtsX; Part of the ABC transporter FtsEX involved in cellular division; Belongs to the ABC-4 integral membrane protein family. FtsX subfamily. (308 aa)
APZ44319.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (850 aa)
Your Current Organism:
Acidihalobacter ferrooxidans
NCBI taxonomy Id: 1765967
Other names: A. ferrooxidans
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