STRINGSTRING
APZ41727.1 APZ41727.1 ispF ispF APZ42237.1 APZ42237.1 xseA xseA APZ42451.1 APZ42451.1 APZ42452.1 APZ42452.1 APZ44549.1 APZ44549.1 APZ42476.1 APZ42476.1 APZ44550.1 APZ44550.1 APZ42477.1 APZ42477.1 dxs dxs ispH ispH APZ42479.1 APZ42479.1 APZ42803.1 APZ42803.1 ispE ispE ispG ispG APZ43232.1 APZ43232.1 dxr dxr APZ43234.1 APZ43234.1 uppS uppS ispD ispD xseB xseB APZ43898.1 APZ43898.1 dxs-2 dxs-2 APZ43900.1 APZ43900.1 folE2 folE2 APZ43984.1 APZ43984.1 ispH-2 ispH-2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APZ41727.1Octaprenyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (322 aa)
ispF2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4-diphosphocytidyl-2- C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP). (157 aa)
APZ42237.1Fatty acid hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
xseAExodeoxyribonuclease VII large subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. (451 aa)
APZ42451.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
APZ42452.1Squalene synthase HpnD; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
APZ44549.1NAD-dependent dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
APZ42476.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
APZ44550.1Squalene--hopene cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (655 aa)
APZ42477.1Phytoene synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (612 aa)
ispH4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (344 aa)
APZ42479.1Hopanoid biosynthesis associated radical SAM protein HpnH; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
APZ42803.1Squalene synthase HpnC; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
ispE4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (281 aa)
ispG4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME- 2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate. Belongs to the IspG family. (421 aa)
APZ43232.1RIP metalloprotease RseP; Derived by automated computational analysis using gene prediction method: Protein Homology. (453 aa)
dxr1-deoxy-D-xylulose-5-phosphate reductoisomerase; Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4- phosphate (MEP); Belongs to the DXR family. (400 aa)
APZ43234.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDS family. (273 aa)
uppSDi-trans,poly-cis-decaprenylcistransferase; Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with (2E,6E)-farnesyl diphosphate (E,E-FPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30Z,34E,38E)-undecaprenyl diphosphate (di- trans,octa-cis-UPP). UPP is the precursor of glycosyl carrier lipid in the biosynthesis of bacterial cell wall polysaccharide components such as peptidoglycan and lipopolysaccharide. (260 aa)
ispD2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Catalyzes the formation of 4-diphosphocytidyl-2-C-methyl-D- erythritol from CTP and 2-C-methyl-D-erythritol 4-phosphate (MEP). (232 aa)
xseBExodeoxyribonuclease VII small subunit; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. (82 aa)
APZ43898.1(2E,6E)-farnesyl diphosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the FPP/GGPP synthase family. (298 aa)
dxs-21-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (628 aa)
APZ43900.16-carboxytetrahydropterin synthase QueD; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
folE2GTP cyclohydrolase; Converts GTP to 7,8-dihydroneopterin triphosphate. (271 aa)
APZ43984.1MATE family efflux transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
ispH-24-hydroxy-3-methylbut-2-enyl diphosphate reductase; Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP/MEP pathway for isoprenoid precursor biosynthesis. Belongs to the IspH family. (311 aa)
Your Current Organism:
Acidihalobacter ferrooxidans
NCBI taxonomy Id: 1765967
Other names: A. ferrooxidans
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.