(10 nodes) Beta-lactamase/transpeptidase-like network (Acidihalobacter ferrooxidans)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APZ42034.1	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology. (689 aa)
	ftsI	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum. (573 aa)
	APZ42335.1	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (842 aa)
	APZ43210.1	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
	APZ43451.1	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits). (785 aa)
	APZ44114.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (398 aa)
	APZ44116.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (401 aa)
	mrdA	Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. (671 aa)
	APZ44127.1	Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. (390 aa)
	APZ44319.1	Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (850 aa)

Your Current Organism:

Acidihalobacter ferrooxidans

NCBI taxonomy Id: 1765967
Other names: A. ferrooxidans

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APZ42034.1	APZ42335.1	BW247_02080	BW247_03880	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.689
APZ42034.1	APZ43451.1	BW247_02080	BW247_10430	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.931
APZ42034.1	APZ44114.1	BW247_02080	BW247_14270	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.514
APZ42034.1	APZ44116.1	BW247_02080	BW247_14280	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.522
APZ42034.1	APZ44127.1	BW247_02080	BW247_14355	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.476
APZ42034.1	APZ44319.1	BW247_02080	BW247_15470	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.676
APZ42034.1	ftsI	BW247_02080	BW247_02690	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.	0.750
APZ42335.1	APZ42034.1	BW247_03880	BW247_02080	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.689
APZ42335.1	APZ43451.1	BW247_03880	BW247_10430	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	0.726
APZ42335.1	APZ44114.1	BW247_03880	BW247_14270	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.447
APZ42335.1	APZ44116.1	BW247_03880	BW247_14280	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.447
APZ42335.1	APZ44127.1	BW247_03880	BW247_14355	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.447
APZ42335.1	ftsI	BW247_03880	BW247_02690	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum.	0.689
APZ42335.1	mrdA	BW247_03880	BW247_14300	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily.	0.695
APZ43210.1	APZ44114.1	BW247_08990	BW247_14270	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.678
APZ43210.1	APZ44116.1	BW247_08990	BW247_14280	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.678
APZ43210.1	APZ44127.1	BW247_08990	BW247_14355	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology.	Peptidase M15; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.678
APZ43451.1	APZ42034.1	BW247_10430	BW247_02080	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein 2; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.931
APZ43451.1	APZ42335.1	BW247_10430	BW247_03880	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Penicillin-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.726
APZ43451.1	APZ44114.1	BW247_10430	BW247_14270	Penicillin-binding protein 1B; Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross- linking of the peptide subunits).	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family.	0.486