STRINGSTRING
APZ44491.1 APZ44491.1 APZ42109.1 APZ42109.1 APZ42190.1 APZ42190.1 APZ42195.1 APZ42195.1 acsA acsA APZ42354.1 APZ42354.1 APZ42440.1 APZ42440.1 APZ42449.1 APZ42449.1 accD accD APZ43112.1 APZ43112.1 APZ44639.1 APZ44639.1 APZ43275.1 APZ43275.1 accA accA prpB prpB APZ43640.1 APZ43640.1 APZ43641.1 APZ43641.1 APZ43726.1 APZ43726.1 BW247_12480 BW247_12480 APZ43928.1 APZ43928.1 sucD sucD sucC sucC APZ44042.1 APZ44042.1 APZ44043.1 APZ44043.1 APZ44209.1 APZ44209.1 APZ44233.1 APZ44233.1 APZ44342.1 APZ44342.1 APZ44384.1 APZ44384.1 ackA ackA APZ41766.1 APZ41766.1 APZ41767.1 APZ41767.1 APZ41857.1 APZ41857.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APZ44491.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
APZ42109.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (292 aa)
APZ42190.1acetyl-CoA acetyltransferase; Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Thiolase family. (394 aa)
APZ42195.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
acsAacetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa)
APZ42354.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
APZ42440.1Phosphate acetyl/butaryl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
APZ42449.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (292 aa)
APZ43112.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
APZ44639.1Acetaldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
APZ43275.1DUF4440 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (127 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (317 aa)
prpBMethylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family. (321 aa)
APZ43640.12-methylcitrate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (381 aa)
APZ43641.12-methylcitrate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (483 aa)
APZ43726.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
BW247_12480Hypothetical protein; Frameshifted; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
APZ43928.1Pyridine nucleotide-disulfide oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
sucDsuccinate--CoA ligase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. (292 aa)
sucCsuccinate--CoA ligase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (391 aa)
APZ44042.1acetyl-CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (149 aa)
APZ44043.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (446 aa)
APZ44209.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (467 aa)
APZ44233.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
APZ44342.1Dihydrolipoyl dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
APZ44384.1NADH-dependent alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (398 aa)
APZ41766.1Phosphate acetyltransferase; Involved in acetate metabolism. In the N-terminal section; belongs to the CobB/CobQ family. (694 aa)
APZ41767.1GNAT family N-acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (896 aa)
APZ41857.1Peroxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (293 aa)
Your Current Organism:
Acidihalobacter ferrooxidans
NCBI taxonomy Id: 1765967
Other names: A. ferrooxidans
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