(33 nodes) Mixed, incl. ESX-1 secretion-associated protein EspC, and ESX-1 secretion-associated protein EspA/EspE-like network (Mycobacterium kansasii)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ARG91874.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (379 aa)
	ARG95602.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
	ARG95603.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (403 aa)
	ARG95605.1	PPE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
	ARG91878.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
	ARG91879.1	Secretion protein EspL; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family. (112 aa)
	ARG91880.1	ESX-1 secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
	ARG91881.1	ESX secretion-associated protein EspG; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
	ARG95606.1	DUF2694 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (210 aa)
	ARG95607.1	Secretion protein EspK; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
	B1T50_12735	PE-PGRS family protein; Incomplete; partial in the middle of a contig; missing start; Derived by automated computational analysis using gene prediction method: Protein Homology. (190 aa)
	espC	ESX-1 secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
	espA	Secretion protein EspA; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
	ARG92956.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
	ARG92958.1	ESX-1 secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
	ARG92959.1	ESX secretion-associated protein EspG; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
	ARG92960.1	DUF2694 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
	ARG92961.1	Type VII secretion AAA-ATPase EccA; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
	ARG92962.1	Type VII secretion protein EccB; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)
	ARG92963.1	Type VII secretion protein EccCa; Derived by automated computational analysis using gene prediction method: Protein Homology. (745 aa)
	ARG92964.1	Type VII secretion protein EccCb; Derived by automated computational analysis using gene prediction method: Protein Homology. (590 aa)
	ARG92965.1	PE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (98 aa)
	ARG95802.1	PPE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
	esxB	WXG100 family type VII secretion target; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the WXG100 family. (100 aa)
	esat6	WXG100 family type VII secretion target; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the WXG100 family. (95 aa)
	ARG92968.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (815 aa)
	ARG92969.1	Type VII secretion integral membrane protein EccD; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
	ARG92970.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (268 aa)
	ARG93022.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (339 aa)
	ARG93572.1	PPE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
	B1T50_23085	AAA family ATPase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (426 aa)
	ARG94341.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (105 aa)
	ARG94342.1	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)

Your Current Organism:

Mycobacterium kansasii

NCBI taxonomy Id: 1768
Other names: ATCC 12478, CIP 104589, DSM 44162, JCM 6379, M. kansasii, NCTC 13024

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARG91874.1	ARG95602.1	B1T50_07680	B1T50_07685	Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.427
ARG91878.1	ARG91879.1	B1T50_07720	B1T50_07725	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Secretion protein EspL; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.	0.927
ARG91878.1	ARG91880.1	B1T50_07720	B1T50_07730	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ESX-1 secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.498
ARG91878.1	ARG91881.1	B1T50_07720	B1T50_07735	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ESX secretion-associated protein EspG; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.714
ARG91878.1	ARG92959.1	B1T50_07720	B1T50_14515	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ESX secretion-associated protein EspG; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.453
ARG91878.1	ARG92962.1	B1T50_07720	B1T50_14530	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type VII secretion protein EccB; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.550
ARG91878.1	ARG92968.1	B1T50_07720	B1T50_14565	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.419
ARG91878.1	ARG92969.1	B1T50_07720	B1T50_14570	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Type VII secretion integral membrane protein EccD; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.455
ARG91878.1	ARG93572.1	B1T50_07720	B1T50_18270	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PPE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.473
ARG91878.1	ARG95602.1	B1T50_07720	B1T50_07685	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.655
ARG91878.1	ARG95605.1	B1T50_07720	B1T50_07715	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PPE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.473
ARG91878.1	ARG95606.1	B1T50_07720	B1T50_07740	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	DUF2694 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.533
ARG91878.1	ARG95607.1	B1T50_07720	B1T50_07745	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Secretion protein EspK; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.950
ARG91878.1	ARG95802.1	B1T50_07720	B1T50_14550	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	PPE family protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.494
ARG91878.1	B1T50_23085	B1T50_07720	B1T50_23085	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	AAA family ATPase; Incomplete; partial in the middle of a contig; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.551
ARG91878.1	esat6	B1T50_07720	B1T50_14560	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	WXG100 family type VII secretion target; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the WXG100 family.	0.531
ARG91878.1	espA	B1T50_07720	B1T50_12745	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	Secretion protein EspA; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.655
ARG91878.1	espC	B1T50_07720	B1T50_12740	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	ESX-1 secretion-associated protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.511
ARG91878.1	esxB	B1T50_07720	B1T50_14555	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	WXG100 family type VII secretion target; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the WXG100 family.	0.534
ARG91879.1	ARG91878.1	B1T50_07725	B1T50_07720	Secretion protein EspL; Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection; Belongs to the YbaB/EbfC family.	Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.	0.927