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| | fliA | FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (238 aa) |
| | nusG | NusG; Participates in transcription elongation, termination and antitermination. (176 aa) |
| | rpoB | RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1401 aa) |
| | rpoC | RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1385 aa) |
| | rpoA | RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (340 aa) |
| | moaA2 | MoaA2; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (324 aa) |
| | hemD | HemD; Porphyrin biosynthesis protein HemD [includes: uroporphyrin-III C-methyltransferase; uroporphyrinogen-III synthase]. (513 aa) |
| | hemC | HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (325 aa) |
| | selA | SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (470 aa) |
| | pyrF | PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (244 aa) |
| | pdxJ | PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (239 aa) |
| | serC | SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) |
| | atpF3 | AtpF3; ATP synthase F0, B' subunit; Belongs to the ATPase B chain family. (141 aa) |
| | atpF2 | AtpF2; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (200 aa) |
| | atpH | AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (183 aa) |
| | atpA2 | AtpA2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (504 aa) |
| | atpG2 | AtpG2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (298 aa) |
| | atpD2 | AtpD2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (472 aa) |
| | atpC2 | AtpC2; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | ACN16581.1 | Predicted nucleoside-diphosphate-sugar pyrophosphorylase. (265 aa) |
| | ACN16487.1 | Putative nicotinamidase-related amidohydrolase. (221 aa) |
| | ACN16467.1 | Conserved hypothetical protein. (295 aa) |
| | trpB | TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (408 aa) |
| | trpA | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (253 aa) |
| | purH2 | PurH2; Bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase]. (227 aa) |
| | purH1 | PurH1; Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase ]. (416 aa) |
| | hemN2 | HemN2; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (382 aa) |
| | dacA | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (487 aa) |
| | hpt | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. (171 aa) |
| | pncA | PncA; Pyrazinamidase/nicotinamidase PncA (PZAase) (nicotine deamidase) (NAMase). (218 aa) |
| | coaE | CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (213 aa) |
| | nadD | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (220 aa) |
| | proA | ProA; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (418 aa) |
| | proB | ProB; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (379 aa) |
| | queA | QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (352 aa) |
| | tgt | Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociatio [...] (370 aa) |
| | ribD | RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (381 aa) |
| | ribE | RibE; Riboflavin synthase, alpha chain RibE. (222 aa) |
| | ribAB | RibAB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (401 aa) |
| | ribH | RibH; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (157 aa) |
| | nusB | NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (143 aa) |
| | rpoZ | RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (68 aa) |
| | folE2 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (261 aa) |
| | ACN16078.1 | Hypothetical protein. (484 aa) |
| | ACN16064.1 | Putative flavin-containing amine oxidoreductase family protein. (464 aa) |
| | capD1 | CapD1; Capsular polysaccharide biosynthesis protein CapD1. (353 aa) |
| | ugd | Ugd; UDP-glucose 6-dehydrogenase Ugd. (443 aa) |
| | ACN16037.1 | Conserved hypothetical protein. (332 aa) |
| | pyrD | PyrD; Catalyzes the conversion of dihydroorotate to orotate. (302 aa) |
| | dnaG9 | DnaG9; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (602 aa) |
| | rpoD | RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (618 aa) |
| | ACN16024.1 | Conserved hypothetical protein. (270 aa) |
| | ACN15979.1 | Putative metal dependent hydrolase. (283 aa) |
| | acsA2 | AcsA2; acetyl-CoA synthetase/acetate-CoA ligase AcsA2 (AMP-binding protein). (635 aa) |
| | acsA1 | AcsA1; acetyl-CoA synthetase/acetate-CoA ligase AcsA1 (AMP-binding protein). (677 aa) |
| | dinP | DinP; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (384 aa) |
| | ACN15946.1 | Hypothetical protein. (273 aa) |
| | ribB | RibB; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate. (217 aa) |
| | ACN15904.1 | Putative galactokinase. (345 aa) |
| | ACN15900.1 | Putative purine nucleoside phosphorylase. (258 aa) |
| | ppqE2 | PpqE2; Coenzyme PQQ synthesis protein PpqE (Radical SAM superfamily). (359 aa) |
| | hemB | HemB; Delta-aminolevulinic acid dehydratase HemB (porphobilinogensynthase); Belongs to the ALAD family. (327 aa) |
| | ppqE1 | PpqE1; Coenzyme PQQ synthesis protein PpqE (Radical SAM superfamily). (395 aa) |
| | rpoN | RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (479 aa) |
| | pyrB | PyrB; Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (312 aa) |
| | pyrC | PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (426 aa) |
| | coaBC | CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (412 aa) |
| | folK | FolK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK. (171 aa) |
| | purB | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (464 aa) |
| | ribF | RibF; Riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)]; Belongs to the ribF family. (309 aa) |
| | pyrG | PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa) |
| | holB | HolB; DNA polymerase III, delta prime subunit HolB. (345 aa) |
| | tmk | Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (227 aa) |
| | ACN15756.1 | Putative hydrolase of the alpha/beta superfamily; Belongs to the CinA family. (423 aa) |
| | ltrA | LtrA; Group II intron-encoded protein LtrA (Includes: Reverse-transcriptase; RNA maturase; DNA endonuclease). (215 aa) |
| | ACN15731.1 | Retron-type reverse transcriptase (RNA-directed DNA polymerase). (246 aa) |
| | ACN15727.1 | Retron-type reverse transcriptase (RNA-directed DNA polymerase). (217 aa) |
| | ACN15726.1 | Putative reverse transcriptase/maturase family protein. (223 aa) |
| | ACN15712.1 | Putative 2-component fusion protein (N: adenylate cyclase-C:G-protein signalling modulator). (1183 aa) |
| | ACN15679.1 | Putative acetyltransferase (GNAT family protein). (164 aa) |
| | purC | PurC; Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC (SAICAR synthetase). (295 aa) |
| | dxs | Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (622 aa) |
| | ACN15631.1 | Fe-S oxidoreductase (radical SAM family protein). (332 aa) |
| | rfbC2 | RfbC2; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa) |
| | rfbC1 | RfbC1; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa) |
| | glmU | GlmU; N-acetylglucosamine-1-phosphate uridyltransferase GlmU. (417 aa) |
| | lipA | LipA; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (288 aa) |
| | holA | HolA; DNA polymerase III, delta subunit. (420 aa) |
| | dnaE | DnaE; DNA polymerase III, alpha subunit DnaE. (1184 aa) |
| | guaB | GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (491 aa) |
| | cmk1 | Cmk1; Cytidine monophosphate kinase Cmk. (231 aa) |
| | ACN15558.1 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (189 aa) |
| | ACN15555.1 | Conserved hypothetical protein. (101 aa) |
| | ACN15551.1 | Putative adenylate cyclase family protein. (552 aa) |
| | rpoH | RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (322 aa) |
| | moeB1 | MoeB1; Molybdopterin biosynthesis protein MoeB. (229 aa) |
| | moeD | MoeD; Molybdopterin converting factor, small subunit MoeD. (76 aa) |
| | cyaA2 | CyaA2; Adenylate cyclase CyaA (ATP pyrophosphate-lyase) (Adenylyl cyclase). (1302 aa) |
| | queH | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (176 aa) |
| | ispL | IspL; UDP-glucose 4-epimerase IspL (Galactowaldenase) (UDP-galactose 4-epimerase). (342 aa) |
| | acoA | AcoA; Acetoin dehydrogenase E1, alpha subunit AcoA. (328 aa) |
| | dsrB1 | DsrB1; Dissimilatory sulfite reductase complex, beta subunit DsrB1 (Hydrogensulfite reductase beta subunit). (281 aa) |
| | nirD | NirD; Heme d1 biosynthesis protein NirD [precursor]. (151 aa) |
| | murA | MurA; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa) |
| | rfbD | RfbD; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (291 aa) |
| | purE | PurE; N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) mutase PurE. (254 aa) |
| | hemL | HemL; Glutamate-1-semialdehyde 2,1-aminomutase HemL. (428 aa) |
| | ACN17408.1 | RsbW; Anti-sigma regulatory factor. (164 aa) |
| | ACN17404.1 | Hypothetical protein. (364 aa) |
| | ACN17354.1 | Putative ABC-type transport system, hydrolase component. (372 aa) |
| | cmk3 | Cmk3; Cytidine monophosphate kinase Cmk. (231 aa) |
| | cbiA2 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (481 aa) |
| | umuC1 | UmuC1; DNA repair protein UmuC. (422 aa) |
| | proC | ProC; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (284 aa) |
| | ACN17105.1 | Conserved hypothetical protein. (77 aa) |
| | cinA | CinA; Competence-damage protein CinA. (325 aa) |
| | cmk2 | Cmk2; Cytidine monophosphate kinase Cmk. (278 aa) |
| | ACN16952.1 | Putative uroporphyrinogen-III decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (314 aa) |
| | apt2 | Apt2; Adenine phosphoribosyltransferase Apt. (186 aa) |
| | ACN15119.1 | Putative dinucleotide-utilizing biosynthesis family protein (molybdopterin and thiamine biosynthesis family protein). (679 aa) |
| | cyaA1 | CyaA1; Adenylate cyclase CyaA (adenylate cyclase family 3 protein). (237 aa) |
| | ACN15018.1 | RNA-directed DNA polymerase (retron-type reverse transcriptase). (294 aa) |
| | guaA1 | GuaA1; Catalyzes the synthesis of GMP from XMP. (509 aa) |
| | dnaB | DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (456 aa) |
| | pdxA | PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (340 aa) |
| | gmk | Gmk; Essential for recycling GMP and indirectly, cGMP. (190 aa) |
| | kdsB | KdsB; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (244 aa) |
| | hldE | HldE; ADP-heptose synthase/bifunctional sugar kinase/adenylyltransferase HldE. (149 aa) |
| | ACN14917.1 | Radical SAM domain protein. (315 aa) |
| | thiN | ThiN; Thiamine pyrophosphokinase ThiN. (211 aa) |
| | thyX | ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (221 aa) |
| | ndk | Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa) |
| | ACN14891.1 | Putative ADP-heptose synthase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (168 aa) |
| | atpB2 | AtpB2; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (229 aa) |
| | atpE2 | AtpE2; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (89 aa) |
| | trpD2 | TrpD2; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa) |
| | trpC | TrpC; Tryptophan biosynthesis protein TrpC (anthranilate synthase complex). (484 aa) |
| | purA | PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | ACN14841.1 | Hypothetical protein. (840 aa) |
| | purQ | PurQ; Phosphoribosylformylglycinamidine synthase I. (273 aa) |
| | purL | PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule f [...] (1001 aa) |
| | pyrH | PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) |
| | rho2 | Rho2; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (415 aa) |
| | adk | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (224 aa) |
| | folC | FolC; Folylpolyglutamate synthase FolC. (480 aa) |
| | rluD1 | RluD1; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (313 aa) |
| | prsA2 | PrsA2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) |
| | folD | FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | dnaX | DnaX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (590 aa) |
| | cobT2 | CobT2; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (701 aa) |
| | trpD1 | TrpD1; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (369 aa) |
| | pdxK | PdxK; Pyridoxal kinase PdxK; Belongs to the pyridoxine kinase family. (291 aa) |
| | thiE | ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (219 aa) |
| | ACN14644.1 | Hypothetical protein. (181 aa) |
| | bioB2 | BioB2; Biotin synthetase (Biotin synthetase). (355 aa) |
| | ACN14590.1 | Putative carbamoylphosphate synthase, large subunit. (385 aa) |
| | polB | PolB; DNA polymerase II PolB. (804 aa) |
| | ACN14550.1 | Hypothetical protein. (165 aa) |
| | moaA1 | MoaA1; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. (329 aa) |
| | ACN14534.1 | Leucine-rich ARM-like family protein. (373 aa) |
| | hemE | HemE; Uroporphyrinogen decarboxylase HemE (URO-D); Belongs to the uroporphyrinogen decarboxylase family. (358 aa) |
| | ACN14463.1 | Putative carbohydrate kinase (PfkB family protein). (321 aa) |
| | purM | PurM; Phosphoribosylformylglycinamidine cyclo-ligase PurM (AIRS). (347 aa) |
| | ACN14457.1 | Conserved hypothetical protein. (175 aa) |
| | atpD1 | AtpD1; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (459 aa) |
| | atpC1 | AtpC1; ATP synthase F1, epsilon subunit. (129 aa) |
| | atpB1 | AtpB1; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (238 aa) |
| | atpE1 | AtpE1; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (92 aa) |
| | atpF1 | AtpF1; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (261 aa) |
| | atpA1 | AtpA1; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (517 aa) |
| | atpG | AtpG; ATP synthase F1, gamma subunit AtpG1. (296 aa) |
| | polA | PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (891 aa) |
| | purN | PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (239 aa) |
| | acsM2 | AcsM2; middle-chain-fatty-acid-acyl-CoA synthetase AcsM2 (AMP-binding protein). (559 aa) |
| | ACN14267.1 | Radical SAM domain family protein. (441 aa) |
| | pyrE | PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (184 aa) |
| | ptpS | PtpS; 6-pyruvoyl tetrahydrobiopterin synthase PtpS. (127 aa) |
| | coaD | CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa) |
| | ACN14220.1 | 5-formyltetrahydrofolate cyclo-ligase (5,10-methenyl-tetrahydrofolate synthetase) (Methenyl-THF synthetase) (MTHFS). (195 aa) |
| | serS | SerS; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | cysG | CysG; Siroheme synthase (uroporphyrin-III C-methyltransferase; precorrin-2 dehydrogenase; sirohydrochlorin ferrochelatase). (221 aa) |
| | hemA | HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (428 aa) |
| | ACN14169.1 | Putative metal-dependent hydrolase (beta-lactamase family II protein). (339 aa) |
| | ACN14166.1 | Putative cytidylate kinase. (256 aa) |
| | argH1 | ArgH1; Argininosuccinate lyase ArgH. (426 aa) |
| | ACN14151.1 | Conserved hypothetical protein. (396 aa) |
| | ACN14120.1 | Hypothetical cytidylate kinase. (279 aa) |
| | aac | Aac; acetoacetyl-CoA synthetase (AMP-binding protein). (649 aa) |
| | purD | PurD; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family. (587 aa) |
| | moaC | MoaC; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. (163 aa) |
| | moaE | MoaE; Molybdopterin converting factor, large subunit MoaE. (119 aa) |
| | mobA | MobA; Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor; Belongs to the MobA family. (207 aa) |
| | moaB | MoaB; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family. (169 aa) |
| | rho1 | Rho1; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (355 aa) |
| | bioF | BioF; 7-keto-8-aminopelargonate synthetase BioF. (406 aa) |
| | acsM1 | AcsM1; middle-chain-fatty-acid-acyl-CoA synthetase AcsM1 (AMP-binding protein). (587 aa) |
| | ACN13992.1 | Cytochrome-c3 hydrogenase, gamma subunit (electron transfer subunit). (275 aa) |
| | folA | FolA; Bifunctional deaminase-reductase/dihydrofolate reductase FolA (DHFR). (167 aa) |
| | ACN13945.1 | Predicted serine/threonine protein kinase PpkA. (727 aa) |
| | ACN13917.1 | NAD-dependent epimerase/dehydratase family protein. (322 aa) |
| | cbiK2 | CbiK2; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (259 aa) |
| | cbiK1 | CbiK1; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (318 aa) |
| | ACN13836.1 | Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (221 aa) |
| | cmk5 | Cmk5; Cytidine monophosphate kinase Cmk. (263 aa) |
| | cmk4 | Cmk4; Cytidine monophosphate kinase Cmk. (270 aa) |
| | ACN13823.1 | Putative molybdopterin biosynthesis protein moeA; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (340 aa) |
| | mop1 | Mop1; Aldehyde oxidoreductase Mop. (905 aa) |
| | ACN13814.1 | Putative phosphoglycerate/bisphosphoglycerate mutase (Phosphoglyceromutase) (PGAM). (203 aa) |
| | thiC | ThiC; Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by D.autotrophicum; Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily. (439 aa) |
| | cobT1 | CobT1; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (353 aa) |
| | rpoE | RpoE; DNA-directed RNA polymerase, specialized sigma subunit RpoE (Sigma-24); Belongs to the sigma-70 factor family. ECF subfamily. (190 aa) |
| | priA | PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (815 aa) |
| | upp | Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) |
| | apt1 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (186 aa) |
| | ACN13633.1 | Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (248 aa) |
| | ACN13631.1 | Putative HTH-type transcriptional regulator. (155 aa) |
| | folP | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (293 aa) |
| | coaX | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (262 aa) |
| | ACN13601.1 | Hypothetical protein. (65 aa) |
| | mobB | MobB; Molybdopterin-guanine dinucleotide biosynthesis protein MobB. (168 aa) |
| | ACN13585.1 | Conserved hypothetical protein. (238 aa) |
| | nusA | NusA; Participates in both transcription termination and antitermination. (482 aa) |
| | ACN13547.1 | Putative bifunctional enzyme ThiED (Thiamine-phosphate pyrophosphorylase / Phosphomethylpyrimidine kinase). (272 aa) |
| | ACN13546.1 | Putative 4-aminobutyrate aminotransferase. (79 aa) |
| | ACN13509.1 | DNA-directed DNA polymerase. (130 aa) |
| | umuC2 | UmuC2; DNA-repair protein UmuC1 (Nucleotidyltransferase protein). (137 aa) |
| | fdhD | FdhD; Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH. Belongs to the FdhD family. (274 aa) |
| | pncB | PncB; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (389 aa) |
| | ACN13417.1 | DNA-directed RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa) |
| | ppnK | PpnK; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa) |
| | moeA2 | MoeA2; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (644 aa) |
| | moeA1 | MoeA1; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. (413 aa) |
| | xpt | Xpt; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa) |
| | ACN13371.1 | Predicted anti-sigma regulatory factor RsbW1 (serine/threonine protein kinase). (153 aa) |
| | cbiL | CbiL; Precorrin-2 C20-methyltransferase CbiL (S-adenosyl-L- methionine--precorrin-2 methyltransferase); Belongs to the precorrin methyltransferase family. (235 aa) |
| | cobL | CobL; Decarboxylating precorrin-6Y C5,15-methyltransferase CobL (Precorrin-6 methyltransferase) (Precorrin-6Y methylase). (418 aa) |
| | cobM | CobM; Precorrin-4 C11-methyltransferase CobM. (260 aa) |
| | cbiG | CbiG; Cobalamin biosynthesis protein CbiG. (393 aa) |
| | cobJ | CobJ; precorrin-3B C17-methyltransferase CobJ (Precorrin-3 methyltransferase) (Precorrin-3 methylase). (294 aa) |
| | cobO | CobO; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (171 aa) |
| | cobQ | CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (500 aa) |
| | cobU | CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (176 aa) |
| | ACN13341.1 | Predicted RNA polymerase ECF-type sigma factor(extracytoplasmic function); Belongs to the sigma-70 factor family. ECF subfamily. (166 aa) |
| | bioB1 | BioB1; Biothin synthethase BioB. (348 aa) |
| | prsA1 | PrsA1; Ribose-phosphate pyrophosphokinase PrsA. (313 aa) |
| | ACN13176.1 | Conserved hypothetical protein. (55 aa) |
| | serA2 | SerA2; D-3-phosphoglycerate dehydrogenase (PGDH) SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa) |
| | pdhA | PdhA; Pyruvate dehydrogenase complex, alpha subunit PdhA (E1 component). (319 aa) |
| | ACN17809.1 | Acetoin catabolism protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (349 aa) |
| | uroD | UroD; Uroporphyrinogen decarboxylase UroD; Belongs to the uroporphyrinogen decarboxylase family. (452 aa) |
| | ACN17778.1 | Conserved hypothetical protein. (225 aa) |
| | acsM4 | AcsM4; middle-chain-fatty-acid-acyl-CoA synthetase AcsM4 (AMP-binding protein). (588 aa) |
| | ACN17676.1 | Putative uridylate kinase. (282 aa) |
| | cbiK3 | CbiK3; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (255 aa) |
| | cobS | CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (253 aa) |
| | ACN17622.1 | Putative histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (371 aa) |
| | cbiB | CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (317 aa) |
| | ACN17455.1 | Putative pyridoxamine-phosphate oxidase. (204 aa) |
| | ACN17425.1 | Putative metal-dependent hydrolase. (274 aa) |
| | ACN17416.1 | Putative Metal-dependent hydrolase. (249 aa) |
| | ACN17994.1 | Conserved hypothetical protein. (140 aa) |
| | ACN17868.1 | Predicted Fe-S oxidoreductase. (302 aa) |
| | carA | CarA; Carbamoyl-phosphate synthase small chain CarA; Belongs to the CarA family. (379 aa) |
| | carB2 | CarB2; Carbamoyl-phosphate synthase, large subunit CarB2; Belongs to the CarB family. (1074 aa) |
| | purF | PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (470 aa) |
| | ACN17823.1 | Putative heme biosynthesis protein. (333 aa) |
| | cbiD | CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (368 aa) |
| | cbiA1 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (486 aa) |
| | cbiC | CbiC; Cobalamin (vitamin B12) biosynthesis protein CbiC (precorrin-8X methylmutase). (204 aa) |
| | dnaN | DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for [...] (371 aa) |
| | mop2 | Mop2; Aldehyde oxidoreductase Mop. (918 aa) |
| | gabT | GabT; 4-aminobutyrate aminotransferase GabT; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (435 aa) |
| | thiM | ThiM; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (309 aa) |
| | coxL | CoxL; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL. (769 aa) |
| | ACN16857.1 | Two-component fusion protein (N:Molybdopterin dehydrogenase, FAD-binding domain-C:Carbon monoxide dehydrogenase medium chain). (275 aa) |
| | srf | Srf; Anti-sigma regulatory factor Srf (sigma-B negative effector/serine-protein kinase). (508 aa) |
| | ACN16802.1 | Hypothetical protein. (277 aa) |
| | nadE | NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (544 aa) |
| | fliI | FliI; Flagellum-specific ATP synthase FliI. (451 aa) |
