Your Input: | |
| | queA | QueA; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (352 aa) |
| | nadD | Putative nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (220 aa) |
| | coaE | CoaE; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (213 aa) |
| | pncA | PncA; Pyrazinamidase/nicotinamidase PncA (PZAase) (nicotine deamidase) (NAMase). (218 aa) |
| | hpt | Hpt; Hypoxanthine-guanine phosphoribosyltransferase Hpt (HGPRT) (HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. (171 aa) |
| | dacA | Conserved hypothetical protein; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. (487 aa) |
| | hemN2 | HemN2; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (382 aa) |
| | purH1 | PurH1; Bifunctional purine biosynthesis protein PurH [Includes: Phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase ]. (416 aa) |
| | purH2 | PurH2; Bifunctional purine biosynthesis protein PurH [includes: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase]. (227 aa) |
| | trpA | TrpA; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (253 aa) |
| | trpB | TrpB; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (408 aa) |
| | ACN16467.1 | Conserved hypothetical protein. (295 aa) |
| | ACN16487.1 | Putative nicotinamidase-related amidohydrolase. (221 aa) |
| | ACN16581.1 | Predicted nucleoside-diphosphate-sugar pyrophosphorylase. (265 aa) |
| | atpC2 | AtpC2; Produces ATP from ADP in the presence of a proton gradient across the membrane. (135 aa) |
| | atpD2 | AtpD2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (472 aa) |
| | atpG2 | AtpG2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (298 aa) |
| | ACN17994.1 | Conserved hypothetical protein. (140 aa) |
| | atpA2 | AtpA2; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (504 aa) |
| | atpH | AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation; Belongs to the ATPase delta chain family. (183 aa) |
| | atpF2 | AtpF2; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (200 aa) |
| | atpF3 | AtpF3; ATP synthase F0, B' subunit; Belongs to the ATPase B chain family. (141 aa) |
| | serC | SerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa) |
| | pdxJ | PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (239 aa) |
| | pyrF | PyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (244 aa) |
| | selA | SelA; Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis. (470 aa) |
| | hemC | HemC; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (325 aa) |
| | hemD | HemD; Porphyrin biosynthesis protein HemD [includes: uroporphyrin-III C-methyltransferase; uroporphyrinogen-III synthase]. (513 aa) |
| | rpoA | RpoA; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (340 aa) |
| | rpoC | RpoC; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1385 aa) |
| | rpoB | RpoB; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1401 aa) |
| | nusG | NusG; Participates in transcription elongation, termination and antitermination. (176 aa) |
| | fliA | FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (238 aa) |
| | fliI | FliI; Flagellum-specific ATP synthase FliI. (451 aa) |
| | nadE | NadE; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (544 aa) |
| | srf | Srf; Anti-sigma regulatory factor Srf (sigma-B negative effector/serine-protein kinase). (508 aa) |
| | ACN16857.1 | Two-component fusion protein (N:Molybdopterin dehydrogenase, FAD-binding domain-C:Carbon monoxide dehydrogenase medium chain). (275 aa) |
| | coxL | CoxL; Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL. (769 aa) |
| | thiM | ThiM; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. (309 aa) |
| | mop2 | Mop2; Aldehyde oxidoreductase Mop. (918 aa) |
| | apt2 | Apt2; Adenine phosphoribosyltransferase Apt. (186 aa) |
| | ACN16952.1 | Putative uroporphyrinogen-III decarboxylase; Belongs to the uroporphyrinogen decarboxylase family. (314 aa) |
| | cmk2 | Cmk2; Cytidine monophosphate kinase Cmk. (278 aa) |
| | cinA | CinA; Competence-damage protein CinA. (325 aa) |
| | ACN17105.1 | Conserved hypothetical protein. (77 aa) |
| | umuC1 | UmuC1; DNA repair protein UmuC. (422 aa) |
| | cbiA2 | CbiA2; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (481 aa) |
| | cmk3 | Cmk3; Cytidine monophosphate kinase Cmk. (231 aa) |
| | ACN17354.1 | Putative ABC-type transport system, hydrolase component. (372 aa) |
| | ACN17404.1 | Hypothetical protein. (364 aa) |
| | aroC3 | AroC3; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (362 aa) |
| | ACN17408.1 | RsbW; Anti-sigma regulatory factor. (164 aa) |
| | ACN17416.1 | Putative Metal-dependent hydrolase. (249 aa) |
| | ACN17425.1 | Putative metal-dependent hydrolase. (274 aa) |
| | ACN17455.1 | Putative pyridoxamine-phosphate oxidase. (204 aa) |
| | cbiB | CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (317 aa) |
| | ACN17622.1 | Putative histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase. (371 aa) |
| | cobS | CobS; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (253 aa) |
| | cbiK3 | CbiK3; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (255 aa) |
| | ACN17676.1 | Putative uridylate kinase. (282 aa) |
| | acsM4 | AcsM4; middle-chain-fatty-acid-acyl-CoA synthetase AcsM4 (AMP-binding protein). (588 aa) |
| | ACN17778.1 | Conserved hypothetical protein. (225 aa) |
| | uroD | UroD; Uroporphyrinogen decarboxylase UroD; Belongs to the uroporphyrinogen decarboxylase family. (452 aa) |
| | ACN17809.1 | Acetoin catabolism protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (349 aa) |
| | pdhA | PdhA; Pyruvate dehydrogenase complex, alpha subunit PdhA (E1 component). (319 aa) |
| | serA2 | SerA2; D-3-phosphoglycerate dehydrogenase (PGDH) SerA; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa) |
| | purF | PurF; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (470 aa) |
| | carB2 | CarB2; Carbamoyl-phosphate synthase, large subunit CarB2; Belongs to the CarB family. (1074 aa) |
| | carA | CarA; Carbamoyl-phosphate synthase small chain CarA; Belongs to the CarA family. (379 aa) |
| | purN | PurN; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (239 aa) |
| | polA | PolA; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (891 aa) |
| | atpG | AtpG; ATP synthase F1, gamma subunit AtpG1. (296 aa) |
| | atpA1 | AtpA1; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family. (517 aa) |
| | atpF1 | AtpF1; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (261 aa) |
| | atpE1 | AtpE1; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (92 aa) |
| | atpB1 | AtpB1; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (238 aa) |
| | atpC1 | AtpC1; ATP synthase F1, epsilon subunit. (129 aa) |
| | atpD1 | AtpD1; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits; Belongs to the ATPase alpha/beta chains family. (459 aa) |
| | ACN14463.1 | Putative carbohydrate kinase (PfkB family protein). (321 aa) |
| | purM | PurM; Phosphoribosylformylglycinamidine cyclo-ligase PurM (AIRS). (347 aa) |
| | hemE | HemE; Uroporphyrinogen decarboxylase HemE (URO-D); Belongs to the uroporphyrinogen decarboxylase family. (358 aa) |
| | ACN14534.1 | Leucine-rich ARM-like family protein. (373 aa) |
| | ACN14550.1 | Hypothetical protein. (165 aa) |
| | polB | PolB; DNA polymerase II PolB. (804 aa) |
| | aroB2 | AroB2; 3-dehydroquinate synthase AroB. (414 aa) |
| | ACN14590.1 | Putative carbamoylphosphate synthase, large subunit. (385 aa) |
| | ACN14644.1 | Hypothetical protein. (181 aa) |
| | thiE | ThiE; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (219 aa) |
| | pdxK | PdxK; Pyridoxal kinase PdxK; Belongs to the pyridoxine kinase family. (291 aa) |
| | trpD1 | TrpD1; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (369 aa) |
| | cobT2 | CobT2; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (701 aa) |
| | dnaX | DnaX; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (590 aa) |
| | folD | FolD; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (286 aa) |
| | prsA2 | PrsA2; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (312 aa) |
| | rluD1 | RluD1; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (313 aa) |
| | folC | FolC; Folylpolyglutamate synthase FolC. (480 aa) |
| | adk | Adk; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (224 aa) |
| | rho2 | Rho2; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (415 aa) |
| | pyrH | PyrH; Catalyzes the reversible phosphorylation of UMP to UDP. (240 aa) |
| | purL | PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule f [...] (1001 aa) |
| | purQ | PurQ; Phosphoribosylformylglycinamidine synthase I. (273 aa) |
| | ACN14841.1 | Hypothetical protein. (840 aa) |
| | purA | PurA; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (429 aa) |
| | trpC | TrpC; Tryptophan biosynthesis protein TrpC (anthranilate synthase complex). (484 aa) |
| | trpD2 | TrpD2; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (339 aa) |
| | atpE2 | AtpE2; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (89 aa) |
| | atpB2 | AtpB2; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. (229 aa) |
| | ACN14891.1 | Putative ADP-heptose synthase; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (168 aa) |
| | ndk | Ndk; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (138 aa) |
| | thyX | ThyX; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant. (221 aa) |
| | thiN | ThiN; Thiamine pyrophosphokinase ThiN. (211 aa) |
| | hldE | HldE; ADP-heptose synthase/bifunctional sugar kinase/adenylyltransferase HldE. (149 aa) |
| | kdsB | KdsB; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (244 aa) |
| | gmk | Gmk; Essential for recycling GMP and indirectly, cGMP. (190 aa) |
| | pdxA | PdxA; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (340 aa) |
| | dnaB | DnaB; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (456 aa) |
| | guaA1 | GuaA1; Catalyzes the synthesis of GMP from XMP. (509 aa) |
| | ACN15018.1 | RNA-directed DNA polymerase (retron-type reverse transcriptase). (294 aa) |
| | cyaA1 | CyaA1; Adenylate cyclase CyaA (adenylate cyclase family 3 protein). (237 aa) |
| | hemL | HemL; Glutamate-1-semialdehyde 2,1-aminomutase HemL. (428 aa) |
| | purE | PurE; N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) mutase PurE. (254 aa) |
| | rfbD | RfbD; Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose; Belongs to the dTDP-4-dehydrorhamnose reductase family. (291 aa) |
| | murA | MurA; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (417 aa) |
| | nirD | NirD; Heme d1 biosynthesis protein NirD [precursor]. (151 aa) |
| | dsrB1 | DsrB1; Dissimilatory sulfite reductase complex, beta subunit DsrB1 (Hydrogensulfite reductase beta subunit). (281 aa) |
| | pheA | PheA; Chorismate mutase/prephenate dehydratase PheA (Includes: chorismate mutase; prephenate dehydratase). (371 aa) |
| | aroE1 | AroE1; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (271 aa) |
| | aroA | AroA; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (439 aa) |
| | aroL | AroL; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | aroC2 | AroC2; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (372 aa) |
| | acoA | AcoA; Acetoin dehydrogenase E1, alpha subunit AcoA. (328 aa) |
| | ispL | IspL; UDP-glucose 4-epimerase IspL (Galactowaldenase) (UDP-galactose 4-epimerase). (342 aa) |
| | queH | Conserved hypothetical protein; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr). (176 aa) |
| | cyaA2 | CyaA2; Adenylate cyclase CyaA (ATP pyrophosphate-lyase) (Adenylyl cyclase). (1302 aa) |
| | rpoH | RpoH; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (322 aa) |
| | ACN15551.1 | Putative adenylate cyclase family protein. (552 aa) |
| | acsM2 | AcsM2; middle-chain-fatty-acid-acyl-CoA synthetase AcsM2 (AMP-binding protein). (559 aa) |
| | pyrE | PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (184 aa) |
| | ptpS | PtpS; 6-pyruvoyl tetrahydrobiopterin synthase PtpS. (127 aa) |
| | coaD | CoaD; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (167 aa) |
| | ACN14220.1 | 5-formyltetrahydrofolate cyclo-ligase (5,10-methenyl-tetrahydrofolate synthetase) (Methenyl-THF synthetase) (MTHFS). (195 aa) |
| | serS | SerS; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (427 aa) |
| | cysG | CysG; Siroheme synthase (uroporphyrin-III C-methyltransferase; precorrin-2 dehydrogenase; sirohydrochlorin ferrochelatase). (221 aa) |
| | hemA | HemA; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (428 aa) |
| | ACN14169.1 | Putative metal-dependent hydrolase (beta-lactamase family II protein). (339 aa) |
| | ACN14166.1 | Putative cytidylate kinase. (256 aa) |
| | argH1 | ArgH1; Argininosuccinate lyase ArgH. (426 aa) |
| | ACN14151.1 | Conserved hypothetical protein. (396 aa) |
| | ACN14120.1 | Hypothetical cytidylate kinase. (279 aa) |
| | aac | Aac; acetoacetyl-CoA synthetase (AMP-binding protein). (649 aa) |
| | aroH | AroH; Phospho-2-dehydro-3-deoxyheptonate aldolase AroH. (448 aa) |
| | purD | PurD; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR); Belongs to the GARS family. (587 aa) |
| | rho1 | Rho1; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (355 aa) |
| | acsM1 | AcsM1; middle-chain-fatty-acid-acyl-CoA synthetase AcsM1 (AMP-binding protein). (587 aa) |
| | ACN13992.1 | Cytochrome-c3 hydrogenase, gamma subunit (electron transfer subunit). (275 aa) |
| | folA | FolA; Bifunctional deaminase-reductase/dihydrofolate reductase FolA (DHFR). (167 aa) |
| | ACN13945.1 | Predicted serine/threonine protein kinase PpkA. (727 aa) |
| | ACN13917.1 | NAD-dependent epimerase/dehydratase family protein. (322 aa) |
| | cbiK2 | CbiK2; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (259 aa) |
| | cbiK1 | CbiK1; Catalyzes the insertion of Co(2+) into sirohydrochlorin. Belongs to the CbiK family. (318 aa) |
| | tyrA | TyrA; Chorismate mutase/prephenate dehydrogenase. (377 aa) |
| | ACN13836.1 | Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (221 aa) |
| | cmk5 | Cmk5; Cytidine monophosphate kinase Cmk. (263 aa) |
| | cmk4 | Cmk4; Cytidine monophosphate kinase Cmk. (270 aa) |
| | mop1 | Mop1; Aldehyde oxidoreductase Mop. (905 aa) |
| | ACN13814.1 | Putative phosphoglycerate/bisphosphoglycerate mutase (Phosphoglyceromutase) (PGAM). (203 aa) |
| | thiC | ThiC; Catalyzes the conversion of aminoimidazole ribotide (AIR) to 5-hydroxybenzimidazole (5-HBI) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Is thus involved in the anaerobic biosynthesis of the benzimidazole lower axial ligand of the cobamide produced by D.autotrophicum; Belongs to the ThiC family. 5-hydroxybenzimidazole synthase subfamily. (439 aa) |
| | cobT1 | CobT1; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (353 aa) |
| | aroB1 | AroB1; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (343 aa) |
| | aroF | AroF; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (350 aa) |
| | rpoE | RpoE; DNA-directed RNA polymerase, specialized sigma subunit RpoE (Sigma-24); Belongs to the sigma-70 factor family. ECF subfamily. (190 aa) |
| | priA | PriA; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (815 aa) |
| | upp | Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (208 aa) |
| | apt1 | Apt1; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (186 aa) |
| | ACN13633.1 | Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (248 aa) |
| | ACN13631.1 | Putative HTH-type transcriptional regulator. (155 aa) |
| | folP | FolP; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (293 aa) |
| | coaX | Conserved hypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. (262 aa) |
| | ACN13601.1 | Hypothetical protein. (65 aa) |
| | aroK | AroK; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (173 aa) |
| | nusA | NusA; Participates in both transcription termination and antitermination. (482 aa) |
| | ACN13547.1 | Putative bifunctional enzyme ThiED (Thiamine-phosphate pyrophosphorylase / Phosphomethylpyrimidine kinase). (272 aa) |
| | ACN13509.1 | DNA-directed DNA polymerase. (130 aa) |
| | umuC2 | UmuC2; DNA-repair protein UmuC1 (Nucleotidyltransferase protein). (137 aa) |
| | pncB | PncB; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (389 aa) |
| | ACN13417.1 | DNA-directed RNA polymerase sigma factor; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa) |
| | ppnK | PpnK; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (276 aa) |
| | xpt | Xpt; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. (193 aa) |
| | ACN13371.1 | Predicted anti-sigma regulatory factor RsbW1 (serine/threonine protein kinase). (153 aa) |
| | cbiL | CbiL; Precorrin-2 C20-methyltransferase CbiL (S-adenosyl-L- methionine--precorrin-2 methyltransferase); Belongs to the precorrin methyltransferase family. (235 aa) |
| | cobL | CobL; Decarboxylating precorrin-6Y C5,15-methyltransferase CobL (Precorrin-6 methyltransferase) (Precorrin-6Y methylase). (418 aa) |
| | cobM | CobM; Precorrin-4 C11-methyltransferase CobM. (260 aa) |
| | cbiG | CbiG; Cobalamin biosynthesis protein CbiG. (393 aa) |
| | cobJ | CobJ; precorrin-3B C17-methyltransferase CobJ (Precorrin-3 methyltransferase) (Precorrin-3 methylase). (294 aa) |
| | cobO | CobO; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (171 aa) |
| | cobQ | CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (500 aa) |
| | cobU | CobU; Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate. (176 aa) |
| | ACN13341.1 | Predicted RNA polymerase ECF-type sigma factor(extracytoplasmic function); Belongs to the sigma-70 factor family. ECF subfamily. (166 aa) |
| | aroC1 | AroC1; Chorismate synthase AroC (5-enolpyruvylshikimate-3-phosphate phospholyase). (78 aa) |
| | prsA1 | PrsA1; Ribose-phosphate pyrophosphokinase PrsA. (313 aa) |
| | cbiD | CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A. (368 aa) |
| | cbiA1 | CbiA1; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (486 aa) |
| | cbiC | CbiC; Cobalamin (vitamin B12) biosynthesis protein CbiC (precorrin-8X methylmutase). (204 aa) |
| | dnaN | DnaN; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for [...] (371 aa) |
| | ACN15555.1 | Conserved hypothetical protein. (101 aa) |
| | ACN15558.1 | Putative transcriptional regulator; Belongs to the UPF0301 (AlgH) family. (189 aa) |
| | cmk1 | Cmk1; Cytidine monophosphate kinase Cmk. (231 aa) |
| | guaB | GuaB; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (491 aa) |
| | dnaE | DnaE; DNA polymerase III, alpha subunit DnaE. (1184 aa) |
| | holA | HolA; DNA polymerase III, delta subunit. (420 aa) |
| | glmU | GlmU; N-acetylglucosamine-1-phosphate uridyltransferase GlmU. (417 aa) |
| | rfbC1 | RfbC1; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa) |
| | rfbC2 | RfbC2; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa) |
| | dxs | Dxs; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (622 aa) |
| | purC | PurC; Phosphoribosylaminoimidazole-succinocarboxamide synthase PurC (SAICAR synthetase). (295 aa) |
| | ACN15679.1 | Putative acetyltransferase (GNAT family protein). (164 aa) |
| | ACN15712.1 | Putative 2-component fusion protein (N: adenylate cyclase-C:G-protein signalling modulator). (1183 aa) |
| | ACN15726.1 | Putative reverse transcriptase/maturase family protein. (223 aa) |
| | ACN15727.1 | Retron-type reverse transcriptase (RNA-directed DNA polymerase). (217 aa) |
| | ACN15731.1 | Retron-type reverse transcriptase (RNA-directed DNA polymerase). (246 aa) |
| | ltrA | LtrA; Group II intron-encoded protein LtrA (Includes: Reverse-transcriptase; RNA maturase; DNA endonuclease). (215 aa) |
| | ACN15756.1 | Putative hydrolase of the alpha/beta superfamily; Belongs to the CinA family. (423 aa) |
| | tmk | Tmk; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (227 aa) |
| | holB | HolB; DNA polymerase III, delta prime subunit HolB. (345 aa) |
| | pyrG | PyrG; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (544 aa) |
| | ribF | RibF; Riboflavin biosynthesis protein RibF [Includes: Riboflavin kinase (Flavokinase); FMN adenylyltransferase (FAD pyrophosphorylase) (FAD synthetase)]; Belongs to the ribF family. (309 aa) |
| | aroQ | AroQ; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (151 aa) |
| | purB | PurB; Adenylosuccinate lyase PurB; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (464 aa) |
| | folK | FolK; 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase FolK. (171 aa) |
| | coaBC | CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (412 aa) |
| | pyrC | PyrC; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (426 aa) |
| | pyrB | PyrB; Aspartate carbamoyltransferase PyrB; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (312 aa) |
| | rpoN | RpoN; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (479 aa) |
| | hemB | HemB; Delta-aminolevulinic acid dehydratase HemB (porphobilinogensynthase); Belongs to the ALAD family. (327 aa) |
| | ACN15900.1 | Putative purine nucleoside phosphorylase. (258 aa) |
| | ACN15904.1 | Putative galactokinase. (345 aa) |
| | ACN15946.1 | Hypothetical protein. (273 aa) |
| | dinP | DinP; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (384 aa) |
| | acsA1 | AcsA1; acetyl-CoA synthetase/acetate-CoA ligase AcsA1 (AMP-binding protein). (677 aa) |
| | acsA2 | AcsA2; acetyl-CoA synthetase/acetate-CoA ligase AcsA2 (AMP-binding protein). (635 aa) |
| | ACN15979.1 | Putative metal dependent hydrolase. (283 aa) |
| | ACN16024.1 | Conserved hypothetical protein. (270 aa) |
| | rpoD | RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (618 aa) |
| | dnaG9 | DnaG9; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (602 aa) |
| | pyrD | PyrD; Catalyzes the conversion of dihydroorotate to orotate. (302 aa) |
| | ACN16037.1 | Conserved hypothetical protein. (332 aa) |
| | ugd | Ugd; UDP-glucose 6-dehydrogenase Ugd. (443 aa) |
| | capD1 | CapD1; Capsular polysaccharide biosynthesis protein CapD1. (353 aa) |
| | ACN16064.1 | Putative flavin-containing amine oxidoreductase family protein. (464 aa) |
| | folE2 | Conserved hypothetical protein; Converts GTP to 7,8-dihydroneopterin triphosphate. (261 aa) |
| | rpoZ | RpoZ; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (68 aa) |
| | aroE2 | AroE2; Shikimate dehydrogenase AroE. (256 aa) |
| | nusB | NusB; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (143 aa) |
| | tgt | Tgt; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociatio [...] (370 aa) |
