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mtnA mtnA ACN13633.1 ACN13633.1 mdeA mdeA speE1 speE1 speD speD cysE1 cysE1 cysA1 cysA1 metH2 metH2 ACN14187.1 ACN14187.1 sseA sseA hom hom ACN14498.1 ACN14498.1 dcyD1 dcyD1 dcyD2 dcyD2 ahcY ahcY metK metK ilvE ilvE cysE2 cysE2 ACN15870.1 ACN15870.1 patB patB asd asd speE2 speE2 ACN16221.1 ACN16221.1 metE metE serC serC serA1 serA1 lysC lysC ACN17453.1 ACN17453.1 ACN17636.1 ACN17636.1 ACN17643.1 ACN17643.1 metX metX
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mtnAPutative translation initiation factor eIF-2B alpha subunit; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (382 aa)
ACN13633.1Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage. (248 aa)
mdeAMdeA; Methionine gamma-lyase MdeA (L-methionase). (401 aa)
speE1SpeE1; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (435 aa)
speDSpeD; Catalyzes the decarboxylation of S-adenosylmethionine to S- adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine; Belongs to the prokaryotic AdoMetDC family. Type 1 subfamily. (285 aa)
cysE1CysE1; Serine O-acetyltransferase CysE1 (bacterial transferase hexapeptide repeat family). (325 aa)
cysA1CysA1; Cysteine synthase CysA1 (O-acetylserine sulfhydrylase A). (309 aa)
metH2MetH2; vitamin-B12 dependent methionine synthase MetH (5-methyltetrahydrofolate--homocysteine methyltransferase). (266 aa)
ACN14187.1Branched-chain amino acid aminotransferase. (353 aa)
sseASseA; Thiosulfate sulfur transferase SseA. (626 aa)
homHomoserine dehydrogenase Hom. (436 aa)
ACN14498.1Rhodanese-like domain/cysteine-rich domain protein. (320 aa)
dcyD1DcyD1; D-cysteine desulfhydrase DcyD. (336 aa)
dcyD2DcyD2; Pyridoxal phosphate dependent D-cysteine desulfhydrase DcyD. (339 aa)
ahcYAhcY; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (479 aa)
metKMetK; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (388 aa)
ilvEIlvE; Branched-chain amino acid aminotransferase IlvE. (279 aa)
cysE2CysE2; Serine O-acetyltransferase CysE2 (bacterial transferase hexapeptide repeat family). (145 aa)
ACN15870.1Conserved hypothetical protein. (388 aa)
patBPatB; PLP-dependent aminotransferase PatB. (401 aa)
asdAsd; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (368 aa)
speE2SpeE2; Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine. (544 aa)
ACN16221.1Putative aspartate/tyrosine/aromatic acid aminotransferase. (394 aa)
metEMetE; 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase MetE (Cobalamin-independent methionine synthase). (368 aa)
serCSerC; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (361 aa)
serA1SerA1; D-3-phosphoglycerate dehydrogenase SerA (PGDH); Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (526 aa)
lysCLysC; Aspartokinase LysC (aspartate kinase); Belongs to the aspartokinase family. (408 aa)
ACN17453.1Methionine synthase I, cobalamin-binding domain protein. (294 aa)
ACN17636.1Probable aspartokinase (Aspartate kinase); Belongs to the aspartokinase family. (454 aa)
ACN17643.1Putative ferredoxin. (143 aa)
metXMetX; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (403 aa)
Your Current Organism:
Desulfobacterium autotrophicum
NCBI taxonomy Id: 177437
Other names: D. autotrophicum HRM2, Desulfobacterium autotrophicum HRM2, Desulfobacterium autotrophicum str. HRM2, Desulfobacterium autotrophicum strain HRM2
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