STRINGSTRING
pyrR pyrR uraA uraA argF argF carB_2 carB_2 carA_2 carA_2 pyrE pyrE pyrD pyrD pyrK_2 pyrK_2 pyrF pyrF pyrC pyrC pyrI pyrI pyrB pyrB carA_3 carA_3 carB_3 carB_3 argH1 argH1 argG argG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
pyrRBifunctional protein PyrR; Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant; Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily. (179 aa)
uraAUracil transporter. (427 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (327 aa)
carB_2Carbamoyl-phosphate synthase large chain. (1060 aa)
carA_2Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (362 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (185 aa)
pyrDDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit; Catalyzes the conversion of dihydroorotate to orotate. (300 aa)
pyrK_2Dihydroorotate oxidase B, electron transfer subunit; Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD(+). (245 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Belongs to the OMP decarboxylase family. Type 2 subfamily. (294 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (397 aa)
pyrIAspartate carbamoyltransferase regulatory chain. (143 aa)
pyrBAspartate carbamoyltransferase; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (307 aa)
carA_3Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (345 aa)
carB_3Carbamoyl-phosphate synthase large chain; Belongs to the CarB family. (1071 aa)
argH1Argininosuccinate lyase 1. (439 aa)
argGArgininosuccinate synthase; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (398 aa)
Your Current Organism:
Clostridium sp. N3C
NCBI taxonomy Id: 1776758
Other names: C. sp. N3C
Server load: low (18%) [HD]