(7 nodes) Glutamine amidotransferase network (Clostridium sp. N3C)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	carA_1	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (357 aa)
	pyrG	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (532 aa)
	carA_2	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (362 aa)
	guaA	GMP synthase; Catalyzes the synthesis of GMP from XMP. (510 aa)
	hisH1	Imidazole glycerol phosphate synthase subunit HisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (201 aa)
	carA_3	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family. (345 aa)
	pabA	Para-aminobenzoate synthase glutamine amidotransferase component II. (192 aa)

Your Current Organism:

Clostridium sp. N3C

NCBI taxonomy Id: 1776758
Other names: C. sp. N3C

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
carA_1	guaA	N3C_0011	N3C_0805	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.687
carA_1	pyrG	N3C_0011	N3C_0013	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.861
carA_2	guaA	N3C_0748	N3C_0805	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.687
carA_2	pyrG	N3C_0748	N3C_0013	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.412
carA_3	guaA	N3C_2226	N3C_0805	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.687
carA_3	pyrG	N3C_2226	N3C_0013	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.412
guaA	carA_1	N3C_0805	N3C_0011	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	0.687
guaA	carA_2	N3C_0805	N3C_0748	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	0.687
guaA	carA_3	N3C_0805	N3C_2226	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	0.687
guaA	hisH1	N3C_0805	N3C_0835	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Imidazole glycerol phosphate synthase subunit HisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	0.845
guaA	pabA	N3C_0805	N3C_2832	GMP synthase; Catalyzes the synthesis of GMP from XMP.	Para-aminobenzoate synthase glutamine amidotransferase component II.	0.655
guaA	pyrG	N3C_0805	N3C_0013	GMP synthase; Catalyzes the synthesis of GMP from XMP.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.993
hisH1	guaA	N3C_0835	N3C_0805	Imidazole glycerol phosphate synthase subunit HisH 1; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.845
pabA	guaA	N3C_2832	N3C_0805	Para-aminobenzoate synthase glutamine amidotransferase component II.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.655
pyrG	carA_1	N3C_0013	N3C_0011	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	0.861
pyrG	carA_2	N3C_0013	N3C_0748	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	0.412
pyrG	carA_3	N3C_0013	N3C_2226	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	Carbamoyl-phosphate synthase small chain; Belongs to the CarA family.	0.412
pyrG	guaA	N3C_0013	N3C_0805	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	GMP synthase; Catalyzes the synthesis of GMP from XMP.	0.993