40 items (Dufourea novaeangliae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	WN55_01719	E3 ubiquitin-protein ligase. (772 aa)
	WN55_07904	Palmitoyl-protein thioesterase 1. (228 aa)
	WN55_01758	Synaptotagmin 1. (418 aa)
	WN55_03837	Endophilin-A. (377 aa)
	WN55_00642	Androgen-induced gene 1 protein. (237 aa)
	WN55_05861	AP-1 complex subunit gamma. (802 aa)
	WN55_06413	Neuropilin and tolloid-like protein 1. (794 aa)
	WN55_04476	Voltage-dependent calcium channel gamma-3 subunit. (388 aa)
	WN55_09669	Wiskott-Aldrich syndrome protein. (556 aa)
	WN55_04561	Endophilin-B1. (296 aa)
	WN55_04542	Voltage-dependent calcium channel gamma-5 subunit. (542 aa)
	WN55_06129	RalA-binding protein 1. (669 aa)
	WN55_10510	DnaJ like protein subfamily C member 13. (2231 aa)
	WN55_10157	Very low-density lipoprotein receptor. (1085 aa)
	WN55_07708	Calcium channel flower. (187 aa)
	WN55_09026	Protein amnionless. (474 aa)
	WN55_09238	Epsin-2. (567 aa)
	WN55_00927	Cyclin-G-associated kinase. (1133 aa)
	WN55_11089	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (122 aa)
	WN55_01082	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (220 aa)
	WN55_00890	Low density lipoprotein receptor adapter protein 1. (307 aa)
	WN55_01858	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family. (471 aa)
	WN55_00351	E3 ubiquitin-protein ligase Su(Dx). (1030 aa)
	WN55_02198	Intersectin-1. (623 aa)
	WN55_02470	Phosrestin-2. (376 aa)
	WN55_02970	Phosphatidylinositol-binding clathrin assembly protein LAP. (865 aa)
	WN55_03044	Phosrestin-1. (541 aa)
	WN55_03471	Dynamin; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (871 aa)
	WN55_04290	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1647 aa)
	WN55_04318	FCH domain only protein 2. (987 aa)
	WN55_04328	Synaptojanin-1. (1152 aa)
	WN55_05218	Beta-arrestin-1. (463 aa)
	WN55_06022	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded. (821 aa)
	WN55_05543	Ras-related protein Rab-5C. (214 aa)
	WN55_06373	Cubilin. (3718 aa)
	WN55_05166	Protein disabled. (1667 aa)
	WN55_06787	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles. (863 aa)
	WN55_07492	Arrestin like protein. (406 aa)
	WN55_06719	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (154 aa)
	WN55_07385	Ras-related protein Ral-a. (226 aa)

Your Current Organism:

Dufourea novaeangliae

NCBI taxonomy Id: 178035
Other names: D. novaeangliae, Dufourea nova-angliae

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
WN55_00351	WN55_00927	A0A154PFH0	A0A154PBG7	E3 ubiquitin-protein ligase Su(Dx).	Cyclin-G-associated kinase.	0.810
WN55_00351	WN55_01719	A0A154PFH0	A0A154PGN2	E3 ubiquitin-protein ligase Su(Dx).	E3 ubiquitin-protein ligase.	0.949
WN55_00351	WN55_02198	A0A154PFH0	A0A154PFW6	E3 ubiquitin-protein ligase Su(Dx).	Intersectin-1.	0.611
WN55_00351	WN55_04290	A0A154PFH0	A0A154PLM2	E3 ubiquitin-protein ligase Su(Dx).	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.736
WN55_00351	WN55_06022	A0A154PFH0	A0A154PPD6	E3 ubiquitin-protein ligase Su(Dx).	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.745
WN55_00351	WN55_09669	A0A154PFH0	A0A154P163	E3 ubiquitin-protein ligase Su(Dx).	Wiskott-Aldrich syndrome protein.	0.671
WN55_00890	WN55_01082	A0A154PEA4	A0A154PDY8	Low density lipoprotein receptor adapter protein 1.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.636
WN55_00890	WN55_01858	A0A154PEA4	A0A154PEZ9	Low density lipoprotein receptor adapter protein 1.	AP-2 complex subunit mu; Belongs to the adaptor complexes medium subunit family.	0.731
WN55_00890	WN55_02198	A0A154PEA4	A0A154PFW6	Low density lipoprotein receptor adapter protein 1.	Intersectin-1.	0.949
WN55_00890	WN55_02970	A0A154PEA4	A0A154PHP6	Low density lipoprotein receptor adapter protein 1.	Phosphatidylinositol-binding clathrin assembly protein LAP.	0.575
WN55_00890	WN55_03837	A0A154PEA4	A0A154NWW4	Low density lipoprotein receptor adapter protein 1.	Endophilin-A.	0.551
WN55_00890	WN55_04290	A0A154PEA4	A0A154PLM2	Low density lipoprotein receptor adapter protein 1.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.737
WN55_00890	WN55_04318	A0A154PEA4	A0A154PLP8	Low density lipoprotein receptor adapter protein 1.	FCH domain only protein 2.	0.610
WN55_00890	WN55_05166	A0A154PEA4	A0A154PQG2	Low density lipoprotein receptor adapter protein 1.	Protein disabled.	0.767
WN55_00890	WN55_05543	A0A154PEA4	A0A154PPM4	Low density lipoprotein receptor adapter protein 1.	Ras-related protein Rab-5C.	0.469
WN55_00890	WN55_05861	A0A154PEA4	A0A154P0G4	Low density lipoprotein receptor adapter protein 1.	AP-1 complex subunit gamma.	0.559
WN55_00890	WN55_06022	A0A154PEA4	A0A154PPD6	Low density lipoprotein receptor adapter protein 1.	Hepatocyte growth factor-regulated tyrosine kinase substrate; Essential role in endosome membrane invagination and formation of multivesicular bodies, MVBs. Required during gastrulation and appears to regulate early embryonic signaling pathways. Inhibits tyrosine kinase receptor signaling by promoting degradation of the tyrosine-phosphorylated, active receptor, potentially by sorting activated receptors into MVBs. The MVBs are then trafficked to the lysosome where their contents are degraded.	0.594
WN55_00890	WN55_06413	A0A154PEA4	A0A154P0T1	Low density lipoprotein receptor adapter protein 1.	Neuropilin and tolloid-like protein 1.	0.669
WN55_00890	WN55_06787	A0A154PEA4	A0A154PR10	Low density lipoprotein receptor adapter protein 1.	AP-2 complex subunit alpha; Adaptins are components of the adapter complexes which link clathrin to receptors in coated vesicles.	0.663
WN55_00890	WN55_09238	A0A154PEA4	A0A154PAD7	Low density lipoprotein receptor adapter protein 1.	Epsin-2.	0.586