STRINGSTRING
cobB cobB cobQ cobQ pyrG pyrG AMW09449.1 AMW09449.1 pdxT pdxT carA carA AMW09073.1 AMW09073.1 AMW08886.1 AMW08886.1 AMW08679.1 AMW08679.1 A4E84_01050 A4E84_01050 AMW14191.1 AMW14191.1 AMW14844.1 AMW14844.1 AMW13631.1 AMW13631.1 AMW13187.1 AMW13187.1 AMW12780.1 AMW12780.1 guaA guaA AMW11923.1 AMW11923.1 A4E84_21555 A4E84_21555 AMW11722.1 AMW11722.1 AMW11673.1 AMW11673.1 purQ purQ AMW11141.1 AMW11141.1 AMW10650.1 AMW10650.1 AMW10543.1 AMW10543.1 AMW09980.1 AMW09980.1 hisH hisH AMW09816.1 AMW09816.1 AMW15711.1 AMW15711.1 AMW14738.1 AMW14738.1 AMW14692.1 AMW14692.1 AMW14631.1 AMW14631.1 AMW14535.1 AMW14535.1 AMW14448.1 AMW14448.1 AMW14192.1 AMW14192.1 AMW14154.1 AMW14154.1 AMW14030.1 AMW14030.1 AMW13981.1 AMW13981.1 AMW13956.1 AMW13956.1 AMW13837.1 AMW13837.1 AMW15015.1 AMW15015.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cobBCobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (487 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (502 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (552 aa)
AMW09449.1Gamma-glutamyl-gamma-aminobutyrate hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (228 aa)
pdxTGlutamine amidotransferase subunit PdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (202 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (380 aa)
AMW09073.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
AMW08886.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (236 aa)
AMW08679.1Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (673 aa)
A4E84_01050Hypothetical protein; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (718 aa)
AMW14191.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (319 aa)
AMW14844.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AMW13631.1Crp/Fnr family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (217 aa)
AMW13187.1Beta-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (660 aa)
AMW12780.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (526 aa)
AMW11923.1Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
A4E84_21555Glycosyl hydrolase; Incomplete; partial on complete genome; missing stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
AMW11722.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
AMW11673.1Anthranilate synthase component II; Aminodeoxychorismate synthase subunit PabA; with PabB catalyzes the formation of 4-amino-4-deoxychorismate from chorismate and glutamine in para-aminobenzoate synthesis; PabA provides the glutamine amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
purQPhosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] (226 aa)
AMW11141.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (337 aa)
AMW10650.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
AMW10543.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
AMW09980.1Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (621 aa)
hisHImidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (216 aa)
AMW09816.1Peptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (351 aa)
AMW15711.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (323 aa)
AMW14738.1Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AMW14692.1AraC family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
AMW14631.1Peptidase C26; Derived by automated computational analysis using gene prediction method: Protein Homology. (231 aa)
AMW14535.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (686 aa)
AMW14448.1Thiamine biosynthesis protein ThiJ; Derived by automated computational analysis using gene prediction method: Protein Homology. (200 aa)
AMW14192.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (211 aa)
AMW14154.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (832 aa)
AMW14030.1Glycosyl hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1240 aa)
AMW13981.1Protease; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
AMW13956.1LD-carboxypeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (310 aa)
AMW13837.1Anthranilate synthase component II; Derived by automated computational analysis using gene prediction method: Protein Homology. (207 aa)
AMW15015.1Catalase HPII; Serves to protect cells from the toxic effects of hydrogen peroxide. (758 aa)
Your Current Organism:
Streptomyces qaidamensis
NCBI taxonomy Id: 1783515
Other names: CGMCC 4.7315, JCM 31184, S. qaidamensis, Streptomyces sp. S10(2016), strain S10
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