STRINGSTRING
metK metK menA menA aroG_2 aroG_2 ispB ispB ctaB ctaB aroA aroA metB_1 metB_1 aroG_1 aroG_1 mdeA mdeA GCA_001049355_04642 GCA_001049355_04642 cysM cysM GCA_001049355_04494 GCA_001049355_04494 nadA nadA thiE thiE folP1 folP1 btuR btuR murA murA GCA_001049355_05486 GCA_001049355_05486 uppS_2 uppS_2 crtM crtM GCA_001049355_02744 GCA_001049355_02744 hemC hemC GCA_001049355_00854 GCA_001049355_00854 metB_2 metB_2 GCA_001049355_05390 GCA_001049355_05390 miaA miaA GCA_001049355_03590 GCA_001049355_03590 folP2 folP2 metZ metZ ribH ribH uppS_1 uppS_1 ribE ribE
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
metKUnannotated protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (428 aa)
menAUnannotated protein; Conversion of 1,4-dihydroxy-2-naphthoate (DHNA) to demethylmenaquinone (DMK); Belongs to the MenA family. Type 1 subfamily. (293 aa)
aroG_2Unannotated protein; Belongs to the class-II DAHP synthase family. (466 aa)
ispBUnannotated protein; Belongs to the FPP/GGPP synthase family. (375 aa)
ctaBUnannotated protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (313 aa)
aroAUnannotated protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (440 aa)
metB_1Unannotated protein. (370 aa)
aroG_1Unannotated protein; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (351 aa)
mdeAUnannotated protein. (447 aa)
GCA_001049355_04642Unannotated protein. (161 aa)
cysMUnannotated protein. (281 aa)
GCA_001049355_04494Unannotated protein. (132 aa)
nadAUnannotated protein; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate. (343 aa)
thiEUnannotated protein; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. (221 aa)
folP1Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (271 aa)
btuRUnannotated protein. (204 aa)
murAUnannotated protein; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (412 aa)
GCA_001049355_05486Unannotated protein; Belongs to the Cob(I)alamin adenosyltransferase family. (198 aa)
uppS_2Unannotated protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (294 aa)
crtMUnannotated protein. (314 aa)
GCA_001049355_02744Unannotated protein. (358 aa)
hemCUnannotated protein; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (311 aa)
GCA_001049355_00854Unannotated protein; Belongs to the UbiA prenyltransferase family. (310 aa)
metB_2Unannotated protein. (393 aa)
GCA_001049355_05390Unannotated protein; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. (263 aa)
miaAUnannotated protein; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. (307 aa)
GCA_001049355_03590Unannotated protein. (859 aa)
folP2Unannotated protein; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (282 aa)
metZUnannotated protein; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (407 aa)
ribHUnannotated protein; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (160 aa)
uppS_1Unannotated protein. (203 aa)
ribEUnannotated protein. (203 aa)
Your Current Organism:
Mycolicibacterium aurum
NCBI taxonomy Id: 1791
Other names: ATCC 23366, CCUG 37666, CIP 104465, DSM 43999, HAMBI 2275, JCM 6366, LMG 19255, LMG:19255, M. aurum, Mycobacterium aurum, NCTC 10437, NRRL B-4037
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.