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asnB_2 asnB_2 pyrG pyrG glnA_1 glnA_1 glnA_2 glnA_2 asnB_1 asnB_1 guaA_1 guaA_1 egtC_1 egtC_1 purF purF purQ purQ egtC_2 egtC_2 glnT_2 glnT_2 glmS_2 glmS_2 KLO53142.1 KLO53142.1 KLO53132.1 KLO53132.1 gltB_3 gltB_3 trpG trpG KLO52494.1 KLO52494.1 glnA_4 glnA_4 KLO51727.1 KLO51727.1 KLO51726.1 KLO51726.1 glnT_1 glnT_1 glmS_1 glmS_1 guaA_2 guaA_2 cobQ cobQ glnA_3 glnA_3 KLO50964.1 KLO50964.1 cobB_2 cobB_2 pdxT pdxT KLO50669.1 KLO50669.1 carA carA hisH hisH gltB_2 gltB_2 glnA3 glnA3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
asnB_2Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (589 aa)
glnA_1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
glnA_2Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
asnB_1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
guaA_1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
egtC_1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (511 aa)
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (224 aa)
egtC_2Amidohydrolase; Catalyzes the hydrolysis of the gamma-glutamyl amide bond of hercynyl-gamma-L-glutamyl-L-cysteine sulfoxide to produce hercynylcysteine sulfoxide, a step in the biosynthesis pathway of ergothioneine. (230 aa)
glnT_2Glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (434 aa)
glmS_2Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
KLO53142.1Protein glxC; Derived by automated computational analysis using gene prediction method: Protein Homology. (232 aa)
KLO53132.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
gltB_3Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1526 aa)
trpGAnthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
KLO52494.1Peptidase C26; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
glnA_4Glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (436 aa)
KLO51727.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
KLO51726.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
glnT_1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (461 aa)
glmS_1Glutamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source. (625 aa)
guaA_2GMP synthase; Catalyzes the synthesis of GMP from XMP. (517 aa)
cobQCobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (482 aa)
glnA_3Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (455 aa)
KLO50964.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
cobB_2Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L- glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. (454 aa)
pdxTGlutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. (193 aa)
KLO50669.1Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
carACarbamoyl phosphate synthase small subunit; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CarA family. (380 aa)
hisHImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (205 aa)
gltB_2Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1522 aa)
glnA3Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (456 aa)
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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