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acpS acpS mmpL13b mmpL13b desA2 desA2 KLO55083.1 KLO55083.1 qor_1 qor_1 KLO53780.1 KLO53780.1 cfa_1 cfa_1 accD3 accD3 KLO53560.1 KLO53560.1 adh_1 adh_1 polS polS KLO53462.1 KLO53462.1 KLO53457.1 KLO53457.1 fadD19_1 fadD19_1 KLO54994.1 KLO54994.1 pks2_1 pks2_1 KLO53415.1 KLO53415.1 mbtL_2 mbtL_2 grsA grsA fabH_2 fabH_2 KLO53069.1 KLO53069.1 ppsC_3 ppsC_3 pks13 pks13 lgrD_2 lgrD_2 ppsC_2 ppsC_2 ytpA_2 ytpA_2 mmpL3 mmpL3 KLO52627.1 KLO52627.1 ppsC_1 ppsC_1 KLO54833.1 KLO54833.1 fabG fabG eryA_3 eryA_3 KLO52544.1 KLO52544.1 pks10 pks10 KLO52128.1 KLO52128.1 KLO52081.1 KLO52081.1 KLO52052.1 KLO52052.1 kasB_2 kasB_2 KLO51904.1 KLO51904.1 KLO51902.1 KLO51902.1 fabD2 fabD2 fabH_1 fabH_1 accC accC KLO51517.1 KLO51517.1 KLO51484.1 KLO51484.1 desA3_1 desA3_1 fadB4 fadB4 mbtM mbtM mbtL_3 mbtL_3 KLO51251.1 KLO51251.1 fabG2 fabG2 KLO54603.1 KLO54603.1 lgrD_4 lgrD_4 KLO51139.1 KLO51139.1 qorA_4 qorA_4 fabG1_1 fabG1_1 inhA inhA pks2_2 pks2_2 KLO50584.1 KLO50584.1 KLO54472.1 KLO54472.1 KLO50388.1 KLO50388.1 KLO50344.1 KLO50344.1 KLO50306.1 KLO50306.1 qorA_3 qorA_3 fabG_16 fabG_16 qorA_2 qorA_2 KLO54421.1 KLO54421.1 fadD6 fadD6 KLO54392.1 KLO54392.1 KLO48316.1 KLO48316.1 KLO48326.1 KLO48326.1 lipA lipA fabD fabD acpP acpP kasA kasA kasB_1 kasB_1 eryA_2 eryA_2 eryA_1 eryA_1 ppsA_2 ppsA_2 adh_2 adh_2 KLO48713.1 KLO48713.1 mbtL_1 mbtL_1 KLO48726.1 KLO48726.1 KLO48759.1 KLO48759.1 qorA_1 qorA_1 KLO48885.1 KLO48885.1 KLO47516.1 KLO47516.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
acpS4'-phosphopantetheinyl transferase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. (130 aa)
mmpL13bMembrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (783 aa)
desA2acyl-ACP desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (275 aa)
KLO55083.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (220 aa)
qor_1NADH oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (380 aa)
KLO53780.1acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
cfa_1Cyclopropane-fatty-acyl-phospholipid synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
accD3acetyl-CoA carboxyl transferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (490 aa)
KLO53560.1acyl-ACP desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
adh_1Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
polSShort-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (250 aa)
KLO53462.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
KLO53457.1Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)
fadD19_1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
KLO54994.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
pks2_1Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2107 aa)
KLO53415.1Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (301 aa)
mbtL_2Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (82 aa)
grsAAmino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1314 aa)
fabH_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (342 aa)
KLO53069.1acyl-ACP desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
ppsC_3NAD(P)H-quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
pks13Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1810 aa)
lgrD_2Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2579 aa)
ppsC_2Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (321 aa)
ytpA_2Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (279 aa)
mmpL3Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1004 aa)
KLO52627.1Acyl dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
ppsC_1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
KLO54833.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
fabG3-ketoacyl-ACP reductase; Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (450 aa)
eryA_3Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3687 aa)
KLO52544.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
pks10Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
KLO52128.1acyl-ACP thioesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
KLO52081.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (177 aa)
KLO52052.1Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (375 aa)
kasB_2FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (415 aa)
KLO51904.13-hydroxyacyl-ACP dehydratase; Functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (154 aa)
KLO51902.13-hydroxyacyl-ACP dehydratase; Functions as a heterodimer along with HadB in fatty acid biosynthesis; fatty acid synthase type II; FAS-II; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0336 family. (169 aa)
fabD2Malonyl CoA-ACP transacylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (205 aa)
fabH_13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (349 aa)
accCacetyl-COA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (597 aa)
KLO51517.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
KLO51484.1fatty-acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
desA3_1stearoyl-CoA 9-desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (412 aa)
fadB4NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
mbtMConverts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
mbtL_3Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (89 aa)
KLO51251.1Dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (150 aa)
fabG23-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (262 aa)
KLO54603.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
lgrD_4Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2565 aa)
KLO51139.1Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
qorA_4NADPH--quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
fabG1_13-oxoacyl-ACP reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (258 aa)
inhAenoyl-ACP reductase; Catalyzes a key regulatory step in fatty acid biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (269 aa)
pks2_2Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2093 aa)
KLO50584.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
KLO54472.1acyl-ACP desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (322 aa)
KLO50388.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
KLO50344.1fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
KLO50306.1Monooxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
qorA_3NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (308 aa)
fabG_16Short-chain dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
qorA_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
KLO54421.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
fadD6long-chain-acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
KLO54392.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
KLO48316.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (315 aa)
KLO48326.1NADPH:quinone reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)
lipARadical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (314 aa)
fabDACP S-malonyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (291 aa)
acpPAcyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. (98 aa)
kasAFabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (416 aa)
kasB_1FabF; beta-ketoacyl-ACP synthase II, KASII; catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP; required for the elongation of short-chain unsaturated acyl-ACP; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (417 aa)
eryA_2Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (997 aa)
eryA_1Beta-ketoacyl synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (448 aa)
ppsA_2Polyketide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1718 aa)
adh_2Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (304 aa)
KLO48713.1Converts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
mbtL_1Acyl carrier protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (87 aa)
KLO48726.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (184 aa)
KLO48759.13-oxoacyl-ACP synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (3080 aa)
qorA_1NADPH:quinone oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
KLO48885.1fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
KLO47516.1acetyl-CoA carboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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