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fcbA2 fcbA2 KLO54603.1 KLO54603.1 lgrD_4 lgrD_4 fadD_7 fadD_7 bclA_2 bclA_2 fadD9 fadD9 lgrD_1 lgrD_1 KLO50584.1 KLO50584.1 KLO50344.1 KLO50344.1 fadD_6 fadD_6 KLO54421.1 KLO54421.1 fadD_5 fadD_5 mbtF mbtF KLO48423.1 KLO48423.1 KLO48373.1 KLO48373.1 KLO48357.1 KLO48357.1 trsA_1 trsA_1 KLO54392.1 KLO54392.1 fadD6 fadD6 fadD36 fadD36 fadD14 fadD14 prpE prpE KLO53896.1 KLO53896.1 fadK_1 fadK_1 fadD_2 fadD_2 fadD35 fadD35 bclA_1 bclA_1 KLO53462.1 KLO53462.1 fadD19_1 fadD19_1 KLO54994.1 KLO54994.1 dhbF_3 dhbF_3 mbtB_2 mbtB_2 mbtB_1 mbtB_1 KLO52575.1 KLO52575.1 fadD_9 fadD_9 fadD4 fadD4 fadK_5 fadK_5 KLO52544.1 KLO52544.1 fadD2 fadD2 trsA_2 trsA_2 lgrD_2 lgrD_2 lgrD_3 lgrD_3 KLO52856.1 KLO52856.1 fadD32 fadD32 dhbE dhbE fadK_4 fadK_4 KLO48713.1 KLO48713.1 fadD10 fadD10 fadD_4 fadD_4 fadK_3 fadK_3 fadD_3 fadD_3 fadK_2 fadK_2 KLO48885.1 KLO48885.1 KLO47591.1 KLO47591.1 KLO47472.1 KLO47472.1 KLO47485.1 KLO47485.1 KLO47503.1 KLO47503.1 acs acs grsA grsA KLO53353.1 KLO53353.1 acsA_1 acsA_1 fadD_1 fadD_1 KLO50151.1 KLO50151.1 fadD19_2 fadD19_2 menE_3 menE_3 fadD_10 fadD_10 menE_1 menE_1 fadD8 fadD8 fadD_8 fadD_8 KLO51517.1 KLO51517.1 KLO51508.1 KLO51508.1 KLO51484.1 KLO51484.1 mbtM mbtM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fcbA2AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
KLO54603.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
lgrD_4Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2565 aa)
fadD_7AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (528 aa)
bclA_2acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)
fadD9Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1156 aa)
lgrD_1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1161 aa)
KLO50584.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (583 aa)
KLO50344.1fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (619 aa)
fadD_6AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (527 aa)
KLO54421.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
fadD_5AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
mbtFPeptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1476 aa)
KLO48423.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (599 aa)
KLO48373.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
KLO48357.1Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (541 aa)
trsA_1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (997 aa)
KLO54392.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (517 aa)
fadD6long-chain-acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; may be involved in acyclic terpene utilization; Derived by automated computational analysis using gene prediction method: Protein Homology. (592 aa)
fadD36acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (468 aa)
fadD14Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (540 aa)
prpECatalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (622 aa)
KLO53896.1Long-chain fatty acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (544 aa)
fadK_1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (518 aa)
fadD_2AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
fadD35AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (538 aa)
bclA_1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
KLO53462.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (503 aa)
fadD19_1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; in Mycobacterium may be involved in virulence; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
KLO54994.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (584 aa)
dhbF_3Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1817 aa)
mbtB_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (244 aa)
mbtB_1Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1181 aa)
KLO52575.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (494 aa)
fadD_9acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (522 aa)
fadD4acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (506 aa)
fadK_5Long-chain fatty acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
KLO52544.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (574 aa)
fadD2acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
trsA_2AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (495 aa)
lgrD_2Peptide synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (2579 aa)
lgrD_3Gramicidin synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ATP-dependent AMP-binding enzyme family. (3441 aa)
KLO52856.1acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (693 aa)
fadD32fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
dhbEEnterobactin synthase subunit E; Derived by automated computational analysis using gene prediction method: Protein Homology. (549 aa)
fadK_4Adenylate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (529 aa)
KLO48713.1Converts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
fadD10acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
fadD_4Fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (493 aa)
fadK_3AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (513 aa)
fadD_3AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (456 aa)
fadK_2AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
KLO48885.1fatty-acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (610 aa)
KLO47591.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
KLO47472.1O-succinylbenzoate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (512 aa)
KLO47485.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (569 aa)
KLO47503.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (532 aa)
acsacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (653 aa)
grsAAmino acid adenylation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1314 aa)
KLO53353.1Long-chain fatty acid--CoA ligase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (542 aa)
acsA_1acetoacetyl-CoA synthetase; AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (642 aa)
fadD_1Fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (514 aa)
KLO50151.1AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
fadD19_2acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
menE_3AMP-dependent synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (482 aa)
fadD_10AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
menE_1O-succinylbenzoic acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
fadD8acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (533 aa)
fadD_8Long-chain fatty acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (521 aa)
KLO51517.1acyl-CoA synthetase; Activates fatty acids by binding to coenzyme A; Derived by automated computational analysis using gene prediction method: Protein Homology. (560 aa)
KLO51508.1acetyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
KLO51484.1fatty-acid--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
mbtMConverts medium- to long-chain aliphatic fatty acids into acyl adenylate; involved in mycobactin synthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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