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glnT_2 glnT_2 glnA_4 glnA_4 aspC_2 aspC_2 KLO52193.1 KLO52193.1 hmp_1 hmp_1 KLO54703.1 KLO54703.1 glnT_1 glnT_1 gdhB_3 gdhB_3 kipI_2 kipI_2 KLO50976.1 KLO50976.1 mdlY mdlY glnA_3 glnA_3 argA argA glnA3 glnA3 ureC ureC ureB ureB ureA ureA gdhB_1 gdhB_1 glnA_1 glnA_1 glnA_2 glnA_2 gdhB_2 gdhB_2 argC argC argJ argJ argB argB argD argD argF argF argG argG argH argH gdhA gdhA arcA arcA purQ purQ aspC_1 aspC_1 gdh gdh
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
glnT_2Glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (434 aa)
glnA_4Glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (436 aa)
aspC_2Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
KLO52193.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
hmp_1Hemin transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the globin family. (411 aa)
KLO54703.1Arginine deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (415 aa)
glnT_1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (461 aa)
gdhB_3Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1032 aa)
kipI_2Urea amidolyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (664 aa)
KLO50976.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
mdlYCatalyzes the hydrolysis of allophanate; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
glnA_3Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (455 aa)
argAN-acetylglutamate synthase; Catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (160 aa)
glnA3Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (456 aa)
ureCUrease subunit alpha; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 ureC (alpha) and 3 ureAB (gamma/beta) subunits; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
ureBUrease subunit beta; Ureases catalyze the hydrolysis of urea into ammonia and carbon dioxide; in Helicobacter pylori and Yersinia enterocolitica the ammonia released plays a key role in bacterial survival by neutralizing acids when colonizing the gastric mucosa; the holoenzyme is composed of 3 UreC (alpha) and 3 UreAB (gamma/beta); Derived by automated computational analysis using gene prediction method: Protein Homology. (104 aa)
ureAUrease subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the urease gamma subunit family. (100 aa)
gdhB_1NAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1617 aa)
glnA_1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
glnA_2Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
gdhB_2Glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (874 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (292 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (404 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (307 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
gdhAConverts 2-oxoglutarate to glutamate; in Escherichia coli this enzyme plays a role in glutamate synthesis when the cell is under energy restriction; uses NADPH; forms a homohexamer; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (449 aa)
arcAArginine deiminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (402 aa)
purQPhosphoribosylformylglycinamidine synthase; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in [...] (224 aa)
aspC_1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
gdhNAD-glutamate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1068 aa)
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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