STRINGSTRING
KLO52494.1 KLO52494.1 KLO52620.1 KLO52620.1 yvoA_2 yvoA_2 KLO52648.1 KLO52648.1 gltB_3 gltB_3 gltD-2 gltD-2 polX polX pheA pheA KLO53020.1 KLO53020.1 pat_2 pat_2 yvoA_3 yvoA_3 KLO53086.1 KLO53086.1 glnA3 glnA3 tdcB tdcB plsC_3 plsC_3 fda fda trpB trpB leuB_1 leuB_1 pyk pyk gltD gltD gltB_2 gltB_2 trpA trpA KLO50534.1 KLO50534.1 trpC trpC trpE trpE leuA_1 leuA_1 hisI hisI hisF hisF priA_1 priA_1 hisH hisH hisB hisB hisC hisC hisD hisD ilvA ilvA acnA acnA KLO46502.1 KLO46502.1 KLO46529.1 KLO46529.1 KLO47357.1 KLO47357.1 KLO47726.1 KLO47726.1 yvoA_1 yvoA_1 tktB tktB dxs_1 dxs_1 gltA1 gltA1 serA2 serA2 rpiB_1 rpiB_1 proB proB proA proA KLO48638.1 KLO48638.1 ltaE ltaE ilvX ilvX cobD_2 cobD_2 glnA_1 glnA_1 glnA_2 glnA_2 ilvE ilvE asnB_1 asnB_1 aroG_1 aroG_1 dapE_3 dapE_3 KLO48342.1 KLO48342.1 metH_1 metH_1 hisE hisE hisG hisG ectB ectB KLO48271.1 KLO48271.1 argC argC argJ argJ argB argB argD argD argF argF argG argG argH argH thrB thrB thrC thrC hom hom lysA_2 lysA_2 dapE_1 dapE_1 dapD dapD dapL dapL KLO54156.1 KLO54156.1 KLO54089.1 KLO54089.1 KLO54027.1 KLO54027.1 glyA glyA metB metB cbs cbs eno eno lysA_1 lysA_1 prs prs ksgA ksgA KLO55063.1 KLO55063.1 KLO55045.1 KLO55045.1 frlR_1 frlR_1 gltA2 gltA2 citA citA serC serC dapC dapC aspC_1 aspC_1 gabT_2-2 gabT_2-2 KLO53230.1 KLO53230.1 cysK_2 cysK_2 asd asd lysC lysC glnT_2 glnT_2 leuA_2 leuA_2 tyrC tyrC dapB_2 dapB_2 dapA_1 dapA_1 argA argA dapF dapF aroG_2 aroG_2 aroE aroE aroC aroC aroK aroK aroB aroB yidP yidP metK_1 metK_1 rpe rpe gapA gapA pgk pgk tpiA tpiA KLO50632.1 KLO50632.1 tal tal KLO50267.1 KLO50267.1 tkt tkt KLO50921.1 KLO50921.1 KLO50964.1 KLO50964.1 glnA_3 glnA_3 asnB_2 asnB_2 KLO50976.1 KLO50976.1 yxeP_1 yxeP_1 pca pca mccB mccB leuD leuD leuC leuC leuB_2 leuB_2 serA_1 serA_1 ilvC ilvC ilvH ilvH ilvB ilvB pfkA pfkA KLO51116.1 KLO51116.1 serB2 serB2 dapA_3 dapA_3 KLO51305.1 KLO51305.1 hisN hisN KLO51421.1 KLO51421.1 aroQ aroQ aroA aroA KLO51529.1 KLO51529.1 maf maf KLO51615.1 KLO51615.1 icd2 icd2 metX metX glnT_1 glnT_1 KLO51726.1 KLO51726.1 KLO51727.1 KLO51727.1 KLO54681.1 KLO54681.1 pat_1 pat_1 ilvG ilvG hmp_1 hmp_1 dmdA_1 dmdA_1 KLO52046.1 KLO52046.1 proC proC gpmA gpmA KLO54754.1 KLO54754.1 KLO52193.1 KLO52193.1 rpiB_2 rpiB_2 frlR_2 frlR_2 fba fba KLO52291.1 KLO52291.1 sdaA sdaA aspC_2 aspC_2 phnF phnF gap gap dmdA_2 dmdA_2 DmdB DmdB cfiB cfiB glnA_4 glnA_4 KLO52521.1 KLO52521.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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KLO52494.1Peptidase C26; Derived by automated computational analysis using gene prediction method: Protein Homology. (241 aa)
KLO52620.1Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (331 aa)
yvoA_2GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (255 aa)
KLO52648.1Dihydroxy-acid dehydratase; Catalyzes the dehydration of 2,3-dihydroxy-3-methylbutanoate to 3-methyl-2-oxobutanoate in valine and isoleucine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
gltB_3Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1526 aa)
gltD-2Glutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (488 aa)
polXHypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (334 aa)
pheAPrephenate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
KLO53020.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (271 aa)
pat_2Aminotransferase; May catalyze the transamination reaction in phenylalanine biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (356 aa)
yvoA_3GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (246 aa)
KLO53086.1Phosphoglycerate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
glnA3Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (456 aa)
tdcBThreonine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (317 aa)
plsC_3Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (254 aa)
fdaFructose-1,6-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate in glycolysis; Derived by automated computational analysis using gene prediction method: Protein Homology. (297 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (433 aa)
leuB_13-isopropylmalate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
pykPyruvate kinase; Catalyzes the formation of phosphoenolpyruvate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (472 aa)
gltDGlutamate synthase is composed of subunits alpha and beta; beta subunit is a flavin adenine dinucleotide-NADPH dependent oxidoreductase; provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate; Derived by automated computational analysis using gene prediction method: Protein Homology. (500 aa)
gltB_2Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1522 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (262 aa)
KLO50534.1Tryptophan synthase subunit beta; Catalyzes the formation of L-tryptophan from L-serine and 1-(indol-3-yl)glycerol 3-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
trpCIndole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (272 aa)
trpEAnthranilate synthase component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentr [...] (518 aa)
leuA_12-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (582 aa)
hisIphosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP. (115 aa)
hisFImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (261 aa)
priA_1Phosphoribosyl isomerase; Involved in both the histidine and tryptophan biosynthetic pathways; Belongs to the HisA/HisF family. (244 aa)
hisHImidazole glycerol phosphate synthase; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (205 aa)
hisBImidazoleglycerol-phosphate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (202 aa)
hisCHistidinol-phosphate aminotransferase; Catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (379 aa)
hisDHistidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (442 aa)
ilvAThreonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (430 aa)
acnAAconitate hydratase; Catalyzes the conversion of citrate to isocitrate; Derived by automated computational analysis using gene prediction method: Protein Homology. (942 aa)
KLO46502.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
KLO46529.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (408 aa)
KLO47357.1Transposase; Derived by automated computational analysis using gene prediction method: Protein Homology. (413 aa)
KLO47726.1Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (103 aa)
yvoA_1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (259 aa)
tktBTransketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
dxs_1Transketolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
gltA1Citrate synthase; Catalyzes the formation of citrate from acetyl-CoA and oxaloacetate; Derived by automated computational analysis using gene prediction method: Protein Homology. (376 aa)
serA22-hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (315 aa)
rpiB_1Catalyzes the interconversion of ribose 5-phosphate to ribulose 5-phosphate; enzyme from E. coli shows allose 6-phosphate isomerase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
proBGamma-glutamyl kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. (366 aa)
proAGamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. (421 aa)
KLO48638.1Histidine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (224 aa)
ltaEThreonine aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
ilvXDecarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (516 aa)
cobD_2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (340 aa)
glnA_1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (446 aa)
glnA_2Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology. (478 aa)
ilvECatalyzes the transamination of the branched-chain amino acids to their respective alpha-keto acids; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
asnB_1Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (654 aa)
aroG_1Phospho-2-dehydro-3-deoxyheptonate aldolase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-II DAHP synthase family. (465 aa)
dapE_3Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (447 aa)
KLO48342.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (223 aa)
metH_1Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1244 aa)
hisEphosphoribosyl-ATP pyrophosphatase; Catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribolsyl)-ATP in histidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (93 aa)
hisGATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. (284 aa)
ectBDiaminobutyrate--2-oxoglutarate aminotransferase; Catalyzes reversively the conversion of L-aspartate beta- semialdehyde (ASA) to L-2,4-diaminobutyrate (DABA) by transamination with L-glutamate; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (428 aa)
KLO48271.1Exlusion protein FxsA; Derived by automated computational analysis using gene prediction method: Protein Homology. (164 aa)
argCN-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (344 aa)
argJN-acetylglutamate synthase; Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis: the synthesis of N-acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate. Belongs to the ArgJ family. (409 aa)
argBAcetylglutamate kinase; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (292 aa)
argDAcetylornithine aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily. (404 aa)
argFOrnithine carbamoyltransferase; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline. (307 aa)
argGArgininosuccinate synthase; Catalyzes the formation of 2-N(omega)-(L-arginino)succinate from L-citrulline and L-aspartate in arginine biosynthesis, AMP-forming; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (399 aa)
argHArgininosuccinate lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (475 aa)
thrBSerine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (315 aa)
thrCThreonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. (366 aa)
homHomoserine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (439 aa)
lysA_2Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (474 aa)
dapE_1Succinyl-diaminopimelate desuccinylase; Catalyzes the formation of succinate and diaminoheptanedioate from succinyldiaminoheptanedioate; Derived by automated computational analysis using gene prediction method: Protein Homology. (354 aa)
dapD2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2-amino-6-oxopimelate using succinyl-CoA. (314 aa)
dapLN-succinyldiaminopimelate aminotransferase; Catalyzes the formation of N-succinyl-LL-2,6-diaminopimelate from N-succinyl-L-2-amino-6-oxopimelate in lysine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (366 aa)
KLO54156.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
KLO54089.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (128 aa)
KLO54027.1Acid phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (299 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (487 aa)
metBCystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (385 aa)
cbsCystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (427 aa)
lysA_1Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (446 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (326 aa)
ksgA16S rRNA methyltransferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (300 aa)
KLO55063.1Shikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (283 aa)
KLO55045.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (90 aa)
frlR_1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (245 aa)
gltA2Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (434 aa)
citACitrate synthase 2; Forms citrate from oxaloacetate and acetyl-CoA; functions in TCA cycle; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the citrate synthase family. (372 aa)
serCPhosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (368 aa)
dapCAminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)
aspC_1Aspartate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (383 aa)
gabT_2-24-aminobutyrate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (441 aa)
KLO53230.1Inhibition of morphological differentiation protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (289 aa)
cysK_2Lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (344 aa)
lysCAspartate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (421 aa)
glnT_2Glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (434 aa)
leuA_22-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily. (598 aa)
tyrCPrephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (314 aa)
dapB_2Dihydrodipicolinate reductase; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate; Belongs to the DapB family. (245 aa)
dapA_1Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (300 aa)
argAN-acetylglutamate synthase; Catalyzes the conversion of l-glutamate to a-N-acetyl-l-glutamate in arginine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the acetyltransferase family. (160 aa)
dapFDiaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (288 aa)
aroG_2Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (352 aa)
aroEShikimate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the shikimate dehydrogenase family. (286 aa)
aroCChorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (399 aa)
aroKShikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (237 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (359 aa)
yidPGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
metK_1S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (399 aa)
rpeRibulose-phosphate 3-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribulose-phosphate 3-epimerase family. (234 aa)
gapAGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (340 aa)
pgkPhosphoglycerate kinase; Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate kinase family. (407 aa)
tpiATriosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (261 aa)
KLO50632.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
talTransaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the transaldolase family. Type 2 subfamily. (371 aa)
KLO50267.1RNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (110 aa)
tktTransketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate. (696 aa)
KLO50921.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
KLO50964.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)
glnA_3Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (455 aa)
asnB_2Asparagine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (601 aa)
KLO50976.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
yxeP_1Amidohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
pcaPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1143 aa)
mccBCystathionine gamma-lyase; Catalyzes the formation of cysteine and 2-oxobutanoate from cystathionine; Derived by automated computational analysis using gene prediction method: Protein Homology. (368 aa)
leuDIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. (197 aa)
leuCIsopropylmalate isomerase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. (484 aa)
leuB_23-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. (336 aa)
serA_13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (528 aa)
ilvCKetol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. (337 aa)
ilvHAcetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (170 aa)
ilvBAcetolactate synthase large subunit; catalyzes the formation of 2-acetolactate from pyruvate; Derived by automated computational analysis using gene prediction method: Protein Homology. (620 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily. (343 aa)
KLO51116.1Methionine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (336 aa)
serB2Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (414 aa)
dapA_3Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family. (335 aa)
KLO51305.1Chorismate mutase; Catalyzes the Claisen rearrangement of chorismate to prephenate. (184 aa)
hisNHistidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (260 aa)
KLO51421.1Aminoglycoside phosphotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (131 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (440 aa)
KLO51529.1Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (192 aa)
mafSeptum formation inhibitor Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (211 aa)
KLO51615.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (410 aa)
icd2Isocitrate dehydrogenase; NADP-specific, catalyzes the formation of 2-oxoglutarate from isocitrate or oxalosuccinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the monomeric-type IDH family. (746 aa)
metXHomoserine acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (376 aa)
glnT_1Glutamine synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (461 aa)
KLO51726.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (238 aa)
KLO51727.1Glutamine amidotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (263 aa)
KLO54681.1Lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology. (419 aa)
pat_1Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (343 aa)
ilvGAcetolactate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (577 aa)
hmp_1Hemin transporter; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the globin family. (411 aa)
dmdA_1Aconitate hydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (651 aa)
KLO52046.1GNAT family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (286 aa)
proCPyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. (290 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (247 aa)
KLO54754.1Haloacid dehalogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (324 aa)
KLO52193.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
rpiB_2Ribose 5-phosphate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
frlR_2GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (253 aa)
fbaFructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (345 aa)
KLO52291.1Dihydrodipicolinate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (359 aa)
sdaASerine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (459 aa)
aspC_2Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (423 aa)
phnFGntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (230 aa)
gapGlyceraldehyde-3-phosphate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (477 aa)
dmdA_23-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (416 aa)
DmdB3-isopropylmalate dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LeuD family. (188 aa)
cfiBPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1134 aa)
glnA_4Glutamate--ammonia ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the glutamine synthetase family. (436 aa)
KLO52521.1Membrane protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (228 aa)
Your Current Organism:
Mycolicibacterium senegalense
NCBI taxonomy Id: 1796
Other names: ATCC 35796, CCUG 21001, CIP 104941, DSM 43656, JCM 15467, Mycobacterium farcinogenes subsp. senegalense, Mycobacterium senegalense, NCTC 10956, strain IEMVT 378
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