STRINGSTRING
AMR77623.1 AMR77623.1 AMR80366.1 AMR80366.1 AMR79254.1 AMR79254.1 thyA thyA AMR79323.1 AMR79323.1 cobD cobD rpoD-2 rpoD-2 dnaG dnaG folE2 folE2 dxs dxs polA polA pdxH pdxH kynU kynU AMR79424.1 AMR79424.1 AMR79436.1 AMR79436.1 AMR79438.1 AMR79438.1 AMR79441.1 AMR79441.1 queC queC nusB nusB AMR79503.1 AMR79503.1 AMR80383.1 AMR80383.1 AMR79533.1 AMR79533.1 pyrB pyrB AMR80384.1 AMR80384.1 AMR79539.1 AMR79539.1 AMR79540.1 AMR79540.1 hemC hemC AMR79544.1 AMR79544.1 dcd dcd cobQ cobQ AMR79583.1 AMR79583.1 cobD-2 cobD-2 AMR79585.1 AMR79585.1 cobS cobS cobT cobT AMR79589.1 AMR79589.1 AMR79608.1 AMR79608.1 AMR79612.1 AMR79612.1 AMR80388.1 AMR80388.1 AMR79675.1 AMR79675.1 AMR79676.1 AMR79676.1 nadA nadA purN purN AMR79684.1 AMR79684.1 AMR79687.1 AMR79687.1 AMR79688.1 AMR79688.1 AMR79693.1 AMR79693.1 purM purM AMR79720.1 AMR79720.1 AMR79721.1 AMR79721.1 AMR79729.1 AMR79729.1 queA queA tgt tgt AMR79761.1 AMR79761.1 AMR79772.1 AMR79772.1 AMR79774.1 AMR79774.1 AMR79782.1 AMR79782.1 thiL thiL AMR79790.1 AMR79790.1 pyrF pyrF aroE aroE aroQ aroQ AMR79806.1 AMR79806.1 AMR79839.1 AMR79839.1 AMR79851.1 AMR79851.1 AMR79853.1 AMR79853.1 AMR79860.1 AMR79860.1 coaE coaE murD murD apaG apaG trpE trpE trpD trpD trpC trpC hemA hemA AMR79989.1 AMR79989.1 murA murA aroB aroB aroK-2 aroK-2 AMR80060.1 AMR80060.1 AMR80407.1 AMR80407.1 rpoA rpoA rpoC rpoC rpoB rpoB nusG nusG AMR80468.1 AMR80468.1 fliA fliA ligD ligD AMR80550.1 AMR80550.1 AMR80608.1 AMR80608.1 AMR80643.1 AMR80643.1 AMR80736.1 AMR80736.1 nadX nadX AMR80838.1 AMR80838.1 AMR80839.1 AMR80839.1 AMR80857.1 AMR80857.1 AMR80896.1 AMR80896.1 AMR80930.1 AMR80930.1 AMR80962.1 AMR80962.1 AMR80977.1 AMR80977.1 AMR80989.1 AMR80989.1 AMR80992.1 AMR80992.1 AMR80995.1 AMR80995.1 AMR81003.1 AMR81003.1 AMR81011.1 AMR81011.1 AMR82360.1 AMR82360.1 upp-2 upp-2 AMR82363.1 AMR82363.1 AMR81231.1 AMR81231.1 AMR81258.1 AMR81258.1 AMR81485.1 AMR81485.1 AMR81504.1 AMR81504.1 dnaE2 dnaE2 AMR81531.1 AMR81531.1 AMR81546.1 AMR81546.1 AMR81557.1 AMR81557.1 AMR81585.1 AMR81585.1 AMR81653.1 AMR81653.1 AMR81763.1 AMR81763.1 pyrD-2 pyrD-2 pyrC-2 pyrC-2 AMR81773.1 AMR81773.1 AMR81795.1 AMR81795.1 AMR81889.1 AMR81889.1 AMR81890.1 AMR81890.1 AMR81891.1 AMR81891.1 AMR81893.1 AMR81893.1 AMR81894.1 AMR81894.1 AMR81899.1 AMR81899.1 ligD-2 ligD-2 AMR81959.1 AMR81959.1 AMR82445.1 AMR82445.1 AMR81962.1 AMR81962.1 AMR81971.1 AMR81971.1 AMR81999.1 AMR81999.1 AMR82014.1 AMR82014.1 AMR82066.1 AMR82066.1 AMR82077.1 AMR82077.1 AMR82132.1 AMR82132.1 AMR82185.1 AMR82185.1 amn amn AMR82296.1 AMR82296.1 AMR76343.1 AMR76343.1 priA priA hemE hemE atpC atpC atpD atpD atpG atpG atpA atpA atpH atpH atpF atpF atpE atpE atpB atpB AMR76400.1 AMR76400.1 AMR80129.1 AMR80129.1 dinB dinB AMR76429.1 AMR76429.1 AMR76479.1 AMR76479.1 AMR76484.1 AMR76484.1 coaX coaX pyrE pyrE thiC thiC AMR76661.1 AMR76661.1 thiG thiG AMR76663.1 AMR76663.1 AMR76668.1 AMR76668.1 AMR76673.1 AMR76673.1 AMR76678.1 AMR76678.1 glmU glmU A2G96_02715 A2G96_02715 AMR76770.1 AMR76770.1 ctaB ctaB rpoH rpoH AMR76775.1 AMR76775.1 coaD coaD prs prs AMR76803.1 AMR76803.1 apt apt queF queF AMR76840.1 AMR76840.1 AMR76841.1 AMR76841.1 AMR76847.1 AMR76847.1 AMR76862.1 AMR76862.1 pyrC pyrC AMR76905.1 AMR76905.1 purH purH pdxA pdxA AMR76933.1 AMR76933.1 purC purC purE purE purK purK queG queG adk adk kdsB kdsB ackA ackA AMR80196.1 AMR80196.1 AMR77057.1 AMR77057.1 AMR77070.1 AMR77070.1 hemL hemL nadE nadE serS serS serC serC AMR80209.1 AMR80209.1 AMR80210.1 AMR80210.1 aroA aroA cmk cmk AMR77166.1 AMR77166.1 hldD hldD dnaE dnaE nadD nadD hemF hemF purD purD upp upp AMR77232.1 AMR77232.1 gmk gmk rpoZ rpoZ AMR77253.1 AMR77253.1 AMR77264.1 AMR77264.1 AMR77268.1 AMR77268.1 AMR80227.1 AMR80227.1 AMR77279.1 AMR77279.1 A2G96_06060 A2G96_06060 AMR77333.1 AMR77333.1 AMR77351.1 AMR77351.1 AMR77437.1 AMR77437.1 ppnK ppnK hemH hemH pyrG pyrG AMR77505.1 AMR77505.1 accA accA AMR80242.1 AMR80242.1 aroC aroC folD folD pyrD pyrD AMR77651.1 AMR77651.1 AMR77654.1 AMR77654.1 AMR80254.1 AMR80254.1 AMR77695.1 AMR77695.1 AMR80256.1 AMR80256.1 ackA-2 ackA-2 AMR77833.1 AMR77833.1 AMR77958.1 AMR77958.1 AMR77970.1 AMR77970.1 AMR78012.1 AMR78012.1 AMR78039.1 AMR78039.1 AMR78054.1 AMR78054.1 AMR78066.1 AMR78066.1 AMR78075.1 AMR78075.1 AMR78084.1 AMR78084.1 AMR78144.1 AMR78144.1 purL purL AMR78187.1 AMR78187.1 AMR78199.1 AMR78199.1 AMR78218.1 AMR78218.1 tmk tmk AMR78223.1 AMR78223.1 rpoD rpoD AMR78269.1 AMR78269.1 AMR80299.1 AMR80299.1 purT purT AMR78460.1 AMR78460.1 queE queE AMR78485.1 AMR78485.1 AMR78586.1 AMR78586.1 guaA guaA guaB guaB pyrH pyrH AMR78831.1 AMR78831.1 AMR78913.1 AMR78913.1 priB priB nusA nusA AMR78969.1 AMR78969.1 AMR78984.1 AMR78984.1 purA purA ndk ndk rpoS rpoS dnaX dnaX rho rho AMR79051.1 AMR79051.1 carB carB carA carA AMR79062.1 AMR79062.1 prpE prpE dnaQ dnaQ purU purU acsA acsA AMR79107.1 AMR79107.1 pdxJ pdxJ AMR79128.1 AMR79128.1 pncB pncB purF purF AMR79172.1 AMR79172.1 accD accD trpA trpA trpB trpB trpF trpF AMR79227.1 AMR79227.1 AMR80364.1 AMR80364.1 AMR80365.1 AMR80365.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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AMR77623.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (185 aa)
AMR80366.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
AMR79254.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (166 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
AMR79323.1Diacylglycerol kinase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (166 aa)
cobDCobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (334 aa)
rpoD-2RNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (758 aa)
dnaGDNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. (603 aa)
folE2GTP cyclohydrolase FolE2; Converts GTP to 7,8-dihydroneopterin triphosphate. (267 aa)
dxs1-deoxy-D-xylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. (638 aa)
polADNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. (939 aa)
pdxHPyridoxamine 5'-phosphate oxidase; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (212 aa)
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (418 aa)
AMR79424.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (567 aa)
AMR79436.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (463 aa)
AMR79438.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (638 aa)
AMR79441.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (184 aa)
queC7-cyano-7-deazaguanine synthase; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family. (227 aa)
nusBN utilization substance protein B; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (171 aa)
AMR79503.1acetoacetyl-CoA synthetase; AcsA; in Sinorhizobium meliloti this enzyme is required for acetoacetate activation; similar to acetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (674 aa)
AMR80383.1Hypothetical protein; Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4-hexulose. Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family. (182 aa)
AMR79533.1Dihydroorotase; Catalyzes the reversible hydrolysis of the amide bond within dihydroorotate. This metabolic intermediate is required for the biosynthesis of pyrimidine nucleotides; Derived by automated computational analysis using gene prediction method: Protein Homology. (427 aa)
pyrBAspartate carbamoyltransferase catalytic subunit; Catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (323 aa)
AMR80384.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the UPF0301 (AlgH) family. (190 aa)
AMR79539.1Heme biosynthesis protein HemY; Derived by automated computational analysis using gene prediction method: Protein Homology. (396 aa)
AMR79540.1uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (711 aa)
hemCHydroxymethylbilane synthase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. (336 aa)
AMR79544.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)
dcdDeoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. (188 aa)
cobQCobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. (505 aa)
AMR79583.1Adenosylcobinamide kinase/adenosylcobinamide phosphate guanyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (234 aa)
cobD-2Cobalamin biosynthesis protein; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. (328 aa)
AMR79585.1Threonine-phosphate decarboxylase; Cobalamin biosynthesis protein; decarboxylates L-threonine-O-3-phosphate to yield (R)-1-amino-2-propanol O-2-phosphate, the precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin; structurally similar to histidinol phosphate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (338 aa)
cobSadenosylcobinamide-GDP ribazoletransferase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. (258 aa)
cobTNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). (346 aa)
AMR79589.1cob(I)yrinic acid a,c-diamide adenosyltransferase; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids. (210 aa)
AMR79608.1DNA polymerase III subunit chi; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
AMR79612.1Cobalamin biosynthesis protein CbiX; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
AMR80388.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the precorrin methyltransferase family. (263 aa)
AMR79675.1L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate. (530 aa)
AMR79676.1Nicotinate-nucleotide diphosphorylase (carboxylating); Catalyzes the formation of pyridine-2,3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the NadC/ModD family. (287 aa)
nadAQuinolinate synthase; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate; Belongs to the quinolinate synthase A family. Type 1 subfamily. (384 aa)
purNPhosphoribosylglycinamide formyltransferase; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (222 aa)
AMR79684.1Bifunctional riboflavin kinase/FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribF family. (337 aa)
AMR79687.1Phosphopantothenate synthase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. (400 aa)
AMR79688.1Aminotransferase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA. (166 aa)
AMR79693.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (153 aa)
purMPhosphoribosylformylglycinamidine cyclo-ligase; Catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (350 aa)
AMR79720.12-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (179 aa)
AMR79721.1Deoxynucleoside kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (213 aa)
AMR79729.1Cobalamin adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (186 aa)
queAS-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). (358 aa)
tgttRNA-guanine(34) transglycosylase; Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, - Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form [...] (376 aa)
AMR79761.1Adenylosuccinate lyase; Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (458 aa)
AMR79772.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AMR79774.1DNA polymerase III subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology. (352 aa)
AMR79782.1Glyoxalase; Derived by automated computational analysis using gene prediction method: Protein Homology. (144 aa)
thiLThiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (326 aa)
AMR79790.1Damage-inducible protein CinA; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (165 aa)
pyrFOrotidine 5'-phosphate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the OMP decarboxylase family. Type 2 subfamily. (272 aa)
aroEShikimate dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). (295 aa)
aroQ3-dehydroquinate dehydratase; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (165 aa)
AMR79806.1acetyl-CoA carboxylase biotin carboxylase subunit; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. (450 aa)
AMR79839.1PaaX family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AMR79851.1Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (395 aa)
AMR79853.1Ribonucleotide-diphosphate reductase subunit alpha; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. (979 aa)
AMR79860.1Hypoxanthine-guanine phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (180 aa)
coaEdephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (208 aa)
murDUDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. (504 aa)
apaGCo2+/Mg2+ efflux protein ApaG; Derived by automated computational analysis using gene prediction method: Protein Homology. (124 aa)
trpEAnthranilate synthase; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia. (505 aa)
trpDAnthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa)
trpCIndole-3-glycerol-phosphate synthase; Involved in tryptophan biosynthesis; amino acid biosynthesis; converts 1-(2-carboxyphenylamino)-1-deoxy-D-ribulose 5-phosphate to C(1)-(3-indolyl)-glycerol 3-phosphate and carbon dioxide and water; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpC family. (267 aa)
hemAglutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA). (434 aa)
AMR79989.1Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (763 aa)
murAUDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. (416 aa)
aroB3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (368 aa)
aroK-2Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (186 aa)
AMR80060.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (179 aa)
AMR80407.1Delta-aminolevulinic acid dehydratase; Catalyzes the formation of porphobilinogen from 5-aminolevulinate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (330 aa)
rpoADNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (326 aa)
rpoCDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1413 aa)
rpoBDNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1368 aa)
nusGTranscription termination/antitermination protein NusG; Participates in transcription elongation, termination and antitermination. (193 aa)
AMR80468.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (143 aa)
fliARNA polymerase sigma factor FliA; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes; Belongs to the sigma-70 factor family. FliA subfamily. (238 aa)
ligDATP-dependent DNA ligase; Catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (839 aa)
AMR80550.1Fumarate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (582 aa)
AMR80608.1acetoacetyl-CoA synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1031 aa)
AMR80643.1Bleomycin resistance protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (121 aa)
AMR80736.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (69 aa)
nadXAspartate dehydrogenase; Specifically catalyzes the NAD or NADP-dependent dehydrogenation of L-aspartate to iminoaspartate. (266 aa)
AMR80838.14-hydroxybenzoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (763 aa)
AMR80839.14-hydroxybenzoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (288 aa)
AMR80857.1Ethanolamine utilization protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
AMR80896.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (408 aa)
AMR80930.1Aldehyde oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (944 aa)
AMR80962.14-hydroxybenzoate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (537 aa)
AMR80977.1Aldehyde oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (736 aa)
AMR80989.1ATP-dependent DNA ligase; Catalyzes the ATP-dependent formation of a phosphodiester at the site of a single strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (557 aa)
AMR80992.1DUF4440 domain-containing protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (133 aa)
AMR80995.1Cobalt chelatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (573 aa)
AMR81003.1CDP-alcohol phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (159 aa)
AMR81011.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
AMR82360.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (136 aa)
upp-2Uracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (228 aa)
AMR82363.1Ompetence-damaged protein; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CinA family. (188 aa)
AMR81231.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1156 aa)
AMR81258.1RNA polymerase subunit sigma-70; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (183 aa)
AMR81485.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (553 aa)
AMR81504.1Acylaldehyde oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (739 aa)
dnaE2Error-prone DNA polymerase; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. (1154 aa)
AMR81531.1Aldehyde oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (758 aa)
AMR81546.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
AMR81557.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (356 aa)
AMR81585.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (76 aa)
AMR81653.1GTP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (252 aa)
AMR81763.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
pyrD-2Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate. (316 aa)
pyrC-2Dihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (347 aa)
AMR81773.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (642 aa)
AMR81795.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
AMR81889.1Heme biosynthesis protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (329 aa)
AMR81890.1Protein nirG; Derived by automated computational analysis using gene prediction method: Protein Homology. (163 aa)
AMR81891.1Protein nirH; Derived by automated computational analysis using gene prediction method: Protein Homology. (172 aa)
AMR81893.1Cytochrome C oxidase Cbb3; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
AMR81894.1uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (257 aa)
AMR81899.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (69 aa)
ligD-2ATP-dependent DNA ligase; Catalyzes the ATP dependent formation of a phosphodiester at the site of a single-strand break in duplex DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (942 aa)
AMR81959.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (335 aa)
AMR82445.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (249 aa)
AMR81962.1dTDP-4-dehydrorhamnose 3,5-epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (183 aa)
AMR81971.1Flagellar protein export ATPase FliI; Derived by automated computational analysis using gene prediction method: Protein Homology. (492 aa)
AMR81999.1RNA polymerase subunit sigma; Bacteria have multiple sigma factors which are active under specific conditions; the sigma factor binds with the catalytic core of RNA polymerase to produce the holoenzyme and directs bacterial core RNA polymerase to specific promoter elements to initiate transcription; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (197 aa)
AMR82014.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (1149 aa)
AMR82066.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (282 aa)
AMR82077.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (156 aa)
AMR82132.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (141 aa)
AMR82185.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (333 aa)
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (503 aa)
AMR82296.1Acetoin catabolism protein X; Derived by automated computational analysis using gene prediction method: Protein Homology. (355 aa)
AMR76343.1Coproporphyrinogen III oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the anaerobic coproporphyrinogen-III oxidase family. (490 aa)
priAPrimosomal protein N; Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. (770 aa)
hemEUroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. (363 aa)
atpCF0F1 ATP synthase subunit epsilon; Produces ATP from ADP in the presence of a proton gradient across the membrane. (138 aa)
atpDF0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (467 aa)
atpGF0F1 ATP synthase subunit gamma; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (291 aa)
atpAF0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (513 aa)
atpHF0F1 ATP synthase subunit delta; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (181 aa)
atpFF0F1 ATP synthase subunit B; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (156 aa)
atpEF0F1 ATP synthase subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (88 aa)
atpBF0F1 ATP synthase subunit A; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (288 aa)
AMR76400.1Phenylalanine-4-hydroxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (309 aa)
AMR80129.14a-hydroxytetrahydrobiopterin dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (99 aa)
dinBDNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. (359 aa)
AMR76429.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (341 aa)
AMR76479.1DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] (371 aa)
AMR76484.1Chromosome segregation protein SMC; Derived by automated computational analysis using gene prediction method: Protein Homology. (572 aa)
coaXType III pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (283 aa)
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (233 aa)
thiCPhosphomethylpyrimidine synthase ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. (626 aa)
AMR76661.1Thiamine biosynthesis protein ThiS; Derived by automated computational analysis using gene prediction method: Protein Homology. (65 aa)
thiGThiazole synthase; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (283 aa)
AMR76663.1Thiamine phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AMR76668.1Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
AMR76673.15-formyltetrahydrofolate cyclo-ligase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the 5-formyltetrahydrofolate cyclo-ligase family. (196 aa)
AMR76678.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (64 aa)
glmUGlucosamine-1-phosphate N-acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. (454 aa)
A2G96_02715Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
AMR76770.1Cytochrome C oxidase subunit I; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
ctaBProtoheme IX farnesyltransferase; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. (314 aa)
rpoHRNA polymerase factor sigma-32; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. (308 aa)
AMR76775.1DNA-binding protein YbiB; Derived by automated computational analysis using gene prediction method: Protein Homology. (330 aa)
coaDPantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (161 aa)
prsRibose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. (317 aa)
AMR76803.1RNA polymerase sigma-54 factor; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. (492 aa)
aptAdenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. (190 aa)
queFpreQ(1) synthase; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). (277 aa)
AMR76840.1Pterin-4-alpha-carbinolamine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology. (117 aa)
AMR76841.1Molybdopterin-guanine dinucleotide biosynthesis protein MobA; Derived by automated computational analysis using gene prediction method: Protein Homology. (201 aa)
AMR76847.1Carbon monoxide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (793 aa)
AMR76862.1NUDIX pyrophosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (166 aa)
pyrCDihydroorotase; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate. (344 aa)
AMR76905.1Hypothetical protein; Involved in the import of queuosine (Q) precursors, required for Q precursor salvage; Belongs to the vitamin uptake transporter (VUT/ECF) (TC 2.A.88) family. Q precursor transporter subfamily. (241 aa)
purHPhosphoribosylaminoimidazolecarboxamide formyltransferase; Involved in de novo purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology. (524 aa)
pdxA4-hydroxythreonine-4-phosphate dehydrogenase; Catalyzes the NAD(P)-dependent oxidation of 4-(phosphooxy)-L- threonine (HTP) into 2-amino-3-oxo-4-(phosphooxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP). (362 aa)
AMR76933.1Magnesium/cobalt efflux protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (295 aa)
purCPhosphoribosylaminoimidazolesuccinocarboxamide synthase; Catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4- carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis; SAICAR synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (302 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (165 aa)
purK5-(carboxyamino)imidazole ribonucleotide synthase; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (414 aa)
queGEpoxyqueuosine reductase; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. (404 aa)
adkAdenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (221 aa)
kdsB3-deoxy-manno-octulosonate cytidylyltransferase; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria. (269 aa)
ackAAcetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (411 aa)
AMR80196.1Catalyzes the formation of acetyl phosphate from acetyl-CoA and phosphate; can also act with other short-chain acyl-CoAs; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
AMR77057.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (465 aa)
AMR77070.1Polyketide cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (132 aa)
hemLGlutamate-1-semialdehyde aminotransferase; Converts (S)-4-amino-5-oxopentanoate to 5-aminolevulinate during the porphyrin biosynthesis pathway; Derived by automated computational analysis using gene prediction method: Protein Homology. (430 aa)
nadENAD(+) synthase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (682 aa)
serSserine--tRNA ligase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec). (434 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (385 aa)
AMR80209.1Chorismate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology. (387 aa)
AMR80210.1Prephenate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (300 aa)
aroA3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (434 aa)
cmkCytidylate kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (222 aa)
AMR77166.1UDP-glucose 6-dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (463 aa)
hldDADP-L-glycero-D-mannoheptose-6-epimerase; Catalyzes the interconversion between ADP-D-glycero-beta-D- manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose; Belongs to the NAD(P)-dependent epimerase/dehydratase family. HldD subfamily. (331 aa)
dnaEDNA polymerase III subunit alpha; Catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time; main replicative polymerase; Derived by automated computational analysis using gene prediction method: Protein Homology. (1170 aa)
nadDNicotinate-nicotinamide nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (235 aa)
hemFCoproporphyrinogen III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. (303 aa)
purDPhosphoribosylamine--glycine ligase; Catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GARS family. (422 aa)
uppUracil phosphoribosyltransferase; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa)
AMR77232.1YggW family oxidoreductase; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. (410 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (224 aa)
rpoZDNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. (67 aa)
AMR77253.1SAM-dependent methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (280 aa)
AMR77264.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (114 aa)
AMR77268.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (365 aa)
AMR80227.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (305 aa)
AMR77279.1Toprim domain protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (895 aa)
A2G96_06060Hypothetical protein; Internal stop; Derived by automated computational analysis using gene prediction method: Protein Homology. (455 aa)
AMR77333.1Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. (351 aa)
AMR77351.1DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (189 aa)
AMR77437.1Phospho-2-dehydro-3-deoxyheptonate aldolase; Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D-arabino- heptulosonate-7-phosphate (DAHP). (359 aa)
ppnKNAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (305 aa)
hemHFerrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (371 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (550 aa)
AMR77505.1AMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (576 aa)
accAacetyl-CoA carboxylase carboxyltransferase subunit alpha; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. (323 aa)
AMR80242.1Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology. (307 aa)
aroCGlutathione S-transferase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (369 aa)
folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (283 aa)
pyrDDihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (346 aa)
AMR77651.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)
AMR77654.1Hypothetical protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (463 aa)
AMR80254.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
AMR77695.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (166 aa)
AMR80256.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
ackA-2Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (377 aa)
AMR77833.1Phosphoribosylpyrophosphate synthetase; Catalyzes the formation of PRPP from ATP and ribose 5-phosphate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ribose-phosphate pyrophosphokinase family. (299 aa)
AMR77958.1RNA polymerase subunit sigma; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (191 aa)
AMR77970.1Phosphohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
AMR78012.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (427 aa)
AMR78039.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (95 aa)
AMR78054.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (877 aa)
AMR78066.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (91 aa)
AMR78075.14-hydroxybenzoate--CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (539 aa)
AMR78084.1Helix-turn-helix transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (362 aa)
AMR78144.1RNA polymerase subunit sigma-24; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (244 aa)
purLPhosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. (1348 aa)
AMR78187.1BolA family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the BolA/IbaG family. (108 aa)
AMR78199.1Nicotinamidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (214 aa)
AMR78218.1GCN5 family acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (142 aa)
tmkdTMP kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. (203 aa)
AMR78223.1DNA polymerase III subunit delta; Catalyzes the DNA-template-directed extension of the 3'-end of a DNA strand; the delta' subunit seems to interact with the gamma subunit to transfer the beta subunit on the DNA; Derived by automated computational analysis using gene prediction method: Protein Homology. (335 aa)
rpoDRNA polymerase sigma factor RpoD; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. (655 aa)
AMR78269.1Has polymerase, DNA-binding and 3'-5' exonuclease activities. In Aeropyrum pernix this protein is sensitive to aphidicolin and stable at 95#C; Derived by automated computational analysis using gene prediction method: Protein Homology. (788 aa)
AMR80299.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
purTPhosphoribosylglycinamide formyltransferase; Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate; Belongs to the PurK/PurT family. (401 aa)
AMR78460.16-carboxy-5,6,7,8-tetrahydropterin synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (158 aa)
queE7-carboxy-7-deazaguanine synthase; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (211 aa)
AMR78485.1FMN adenylyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (285 aa)
AMR78586.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (212 aa)
guaAGlutamine-hydrolyzing GMP synthase; Catalyzes the synthesis of GMP from XMP. (539 aa)
guaBIMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (487 aa)
pyrHUMP kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (236 aa)
AMR78831.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (499 aa)
AMR78913.1Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (463 aa)
priBPrimosomal replication protein N; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family. (99 aa)
nusATranscription termination/antitermination protein NusA; Participates in both transcription termination and antitermination. (491 aa)
AMR78969.1Damage-inducible protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (274 aa)
AMR78984.1Nicotinate phosphoribosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (189 aa)
purAAdenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (446 aa)
ndkNucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (141 aa)
rpoSRNA polymerase sigma factor RpoS; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and the general stress response. (395 aa)
dnaXDNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. (792 aa)
rhoTranscription termination factor Rho; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (420 aa)
AMR79051.1Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. (288 aa)
carBCarbamoyl phosphate synthase large subunit; Four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; Derived by automated computational analysis using gene prediction method: Protein Homology. (1082 aa)
carACarbamoyl-phosphate synthase small subunit; Catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; Derived by automated computational analysis using gene prediction method: Protein Homology. (378 aa)
AMR79062.12-aminobenzoate-CoA ligase; Derived by automated computational analysis using gene prediction method: Protein Homology. (565 aa)
prpECatalyzes the formation of propionyl-CoA using propionate as a substrate; PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A; not expressed in Escherichia coli when grown on propionate/minimal media; ATP-dependent; Derived by automated computational analysis using gene prediction method: Protein Homology. (630 aa)
dnaQDNA polymerase III subunit epsilon; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'- 5' exonuclease. (243 aa)
purUFormyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (288 aa)
acsAAcetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (660 aa)
AMR79107.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (135 aa)
pdxJPyridoxine 5'-phosphate synthase; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (260 aa)
AMR79128.1RNA polymerase sigma factor RpoE; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the sigma-70 factor family. ECF subfamily. (199 aa)
pncBNicotinate phosphoribosyltransferase; Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP; Belongs to the NAPRTase family. (392 aa)
purFAmidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. (509 aa)
AMR79172.1Bifunctional folylpolyglutamate synthase/dihydrofolate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the folylpolyglutamate synthase family. (436 aa)
accDacetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA; Belongs to the AccD/PCCB family. (290 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa)
trpFN-(5'-phosphoribosyl)anthranilate isomerase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the TrpF family. (240 aa)
AMR79227.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (90 aa)
AMR80364.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
AMR80365.1Group II intron reverse transcriptase/maturase; Derived by automated computational analysis using gene prediction method: Protein Homology. (443 aa)
Your Current Organism:
Cupriavidus nantongensis
NCBI taxonomy Id: 1796606
Other names: C. nantongensis, Cupriavidus nantongensis Sun et al. 2016, Cupriavidus sp. X1, KCTC 42909, LMG 29218, LMG:29218, strain X1
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