STRINGSTRING
AMR80239.1 AMR80239.1 AMR76317.1 AMR76317.1 AMR76332.1 AMR76332.1 gcvT gcvT gcvH gcvH gcvP gcvP AMR76350.1 AMR76350.1 AMR76386.1 AMR76386.1 AMR76429.1 AMR76429.1 AMR76458.1 AMR76458.1 AMR76467.1 AMR76467.1 AMR76616.1 AMR76616.1 AMR76657.1 AMR76657.1 gpmA gpmA ilvA ilvA AMR76893.1 AMR76893.1 AMR76899.1 AMR76899.1 AMR76904.1 AMR76904.1 AMR76915.1 AMR76915.1 srkA srkA AMR77050.1 AMR77050.1 serC serC AMR77356.1 AMR77356.1 AMR77411.1 AMR77411.1 AMR77531.1 AMR77531.1 AMR77568.1 AMR77568.1 AMR77605.1 AMR77605.1 AMR77879.1 AMR77879.1 AMR78114.1 AMR78114.1 AMR78245.1 AMR78245.1 AMR78306.1 AMR78306.1 merA merA AMR78775.1 AMR78775.1 AMR78840.1 AMR78840.1 AMR78850.1 AMR78850.1 AMR78904.1 AMR78904.1 AMR78905.1 AMR78905.1 AMR78955.1 AMR78955.1 AMR79150.1 AMR79150.1 trpA trpA trpB trpB asd asd AMR80360.1 AMR80360.1 AMR79259.1 AMR79259.1 AMR79353.1 AMR79353.1 thrB thrB AMR79367.1 AMR79367.1 glyA glyA AMR80420.1 AMR80420.1 AMR80575.1 AMR80575.1 AMR80582.1 AMR80582.1 AMR80591.1 AMR80591.1 AMR80672.1 AMR80672.1 AMR82326.1 AMR82326.1 AMR80755.1 AMR80755.1 AMR80759.1 AMR80759.1 AMR80770.1 AMR80770.1 AMR80829.1 AMR80829.1 kbl kbl AMR80896.1 AMR80896.1 AMR82344.1 AMR82344.1 AMR81001.1 AMR81001.1 AMR81039.1 AMR81039.1 AMR82359.1 AMR82359.1 AMR81370.1 AMR81370.1 AMR81470.1 AMR81470.1 AMR81489.1 AMR81489.1 AMR81607.1 AMR81607.1 AMR81609.1 AMR81609.1 AMR81628.1 AMR81628.1 AMR81712.1 AMR81712.1 AMR81732.1 AMR81732.1 AMR81733.1 AMR81733.1 betA betA AMR81795.1 AMR81795.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AMR80239.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AMR76317.1Arsenate reductase (glutaredoxin); Derived by automated computational analysis using gene prediction method: Protein Homology. (119 aa)
AMR76332.1Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (437 aa)
gcvTGlycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine. (375 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
gcvPGlycine dehydrogenase (aminomethyl-transferring); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (976 aa)
AMR76350.1L-serine ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. (458 aa)
AMR76386.1Choline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (567 aa)
AMR76429.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (341 aa)
AMR76458.1GMC family oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (531 aa)
AMR76467.1Succinylglutamate desuccinylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (325 aa)
AMR76616.1Glyoxylate/hydroxypyruvate reductase A; Derived by automated computational analysis using gene prediction method: Protein Homology. (313 aa)
AMR76657.1GMC family oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (559 aa)
gpmAPhosphoglyceromutase; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (248 aa)
ilvAPLP-dependent threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. (512 aa)
AMR76893.1Hydroxypyruvate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (435 aa)
AMR76899.1phytanoyl-CoA dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (265 aa)
AMR76904.1Phosphoglycerate mutase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the phosphoglycerate mutase family. (224 aa)
AMR76915.1Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family. (470 aa)
srkAStress response kinase A; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response. (352 aa)
AMR77050.1Hydroxyacid dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
serC3-phosphoserine/phosphohydroxythreonine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. (385 aa)
AMR77356.1CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (293 aa)
AMR77411.1Fructose-2,6-bisphosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (242 aa)
AMR77531.1Aspartate kinase; Catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aspartokinase family. (417 aa)
AMR77568.1Zinc-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (126 aa)
AMR77605.1Dihydrolipoamide dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (595 aa)
AMR77879.1Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (140 aa)
AMR78114.1Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. (284 aa)
AMR78245.1HAD family hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (360 aa)
AMR78306.1Glucose-methanol-choline oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology. (535 aa)
merAHypothetical protein; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (561 aa)
AMR78775.1Arsenate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ArsC family. (115 aa)
AMR78840.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (116 aa)
AMR78850.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (441 aa)
AMR78904.1Threonine synthase; Catalyzes the formation of L-threonine from O-phospho-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (481 aa)
AMR78905.1Homoserine dehydrogenase; Catalyzes the formation of L-aspartate 4-semialdehyde from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. (436 aa)
AMR78955.1Dihydrolipoyl dehydrogenase; Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (474 aa)
AMR79150.1D-glycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (331 aa)
trpATryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (265 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (397 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (378 aa)
AMR80360.1E3 component of alpha keto acid dehydrogenase complexes LpdC; forms a homodimer; binds one molecule of FAD monomer; catalyzes NAD+-dependent oxidation of dihydrolipoyl cofactors that are covalently linked to the E2 component; Derived by automated computational analysis using gene prediction method: Protein Homology. (464 aa)
AMR79259.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (154 aa)
AMR79353.1Rieske (2Fe-2S) protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (367 aa)
thrBHomoserine kinase; Catalyzes the formation of O-phospho-L-homoserine from L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the pseudomonas-type ThrB family. (334 aa)
AMR79367.1Threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. (343 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (415 aa)
AMR80420.1phytanoyl-CoA dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (273 aa)
AMR80575.1Amine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)
AMR80582.1Diaminopropionate ammonia-lyase; Derived by automated computational analysis using gene prediction method: Protein Homology. (407 aa)
AMR80591.1Ring-hydroxylating oxygenase subunit alpha; Converts carnitine to trimethylamine and malic semialdehyde. (378 aa)
AMR80672.1Serine dehydratase; Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine; Derived by automated computational analysis using gene prediction method: Protein Homology. (320 aa)
AMR82326.1MFS transporter; Derived by automated computational analysis using gene prediction method: Protein Homology. (555 aa)
AMR80755.1Amino acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (434 aa)
AMR80759.1phytanoyl-CoA dioxygenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (278 aa)
AMR80770.1Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (246 aa)
AMR80829.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (492 aa)
kblGlycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. (399 aa)
AMR80896.1D-3-phosphoglycerate dehydrogenase; Catalyzes the formation of 3-phosphonooxypyruvate from 3-phospho-D-glycerate in serine biosynthesis; can also reduce alpha ketoglutarate to form 2-hydroxyglutarate; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (408 aa)
AMR82344.1FAD-dependent oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. (826 aa)
AMR81001.1Aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (243 aa)
AMR81039.1Choline dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. (551 aa)
AMR82359.1XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (74 aa)
AMR81370.1Amino acid deaminase; Derived by automated computational analysis using gene prediction method: Protein Homology. (422 aa)
AMR81470.1CDP-diacylglycerol--serine O-phosphatidyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. (212 aa)
AMR81489.1Catalyzes the oxidation of dihydrolipoamide to lipoamide; Derived by automated computational analysis using gene prediction method: Protein Homology. (466 aa)
AMR81607.1Alanine racemase; Derived by automated computational analysis using gene prediction method: Protein Homology. (384 aa)
AMR81609.1Serine--glyoxylate aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (406 aa)
AMR81628.1Aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family. (396 aa)
AMR81712.1Threonine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. (390 aa)
AMR81732.1Ring-hydroxylating oxygenase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology. (372 aa)
AMR81733.1Betaine-aldehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family. (488 aa)
betACholine dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate. (576 aa)
AMR81795.13-phosphoglycerate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (311 aa)
Your Current Organism:
Cupriavidus nantongensis
NCBI taxonomy Id: 1796606
Other names: C. nantongensis, Cupriavidus nantongensis Sun et al. 2016, Cupriavidus sp. X1, KCTC 42909, LMG 29218, LMG:29218, strain X1
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